# STOCKHOLM 1.0 #=GF ID 1.20.1540.10/FF/000037 #=GF DE Rhomboid family intramembrane serine protease #=GF AC 1.20.1540.10/FF/000037 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 40.128 #=GS Q9XA09/79-290 AC Q9XA09 #=GS Q9XA09/79-290 OS Streptomyces coelicolor A3(2) #=GS Q9XA09/79-290 DE Putative membrane protein #=GS Q9XA09/79-290 DR ORG; Bacteria; Actinobacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group; Streptomyces coelicolor; #=GS O53632/31-206 AC O53632 #=GS O53632/31-206 OS Mycobacterium tuberculosis H37Rv #=GS O53632/31-206 DE Probable conserved integral membrane protein #=GS O53632/31-206 DR ORG; Bacteria; Actinobacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex; Mycobacterium tuberculosis; #=GS A0A3Q8VU81/84-294 AC A0A3Q8VU81 #=GS A0A3Q8VU81/84-294 OS Streptomyces sp. KPB2 #=GS A0A3Q8VU81/84-294 DE Rhomboid family intramembrane serine protease #=GS A0A3Q8VU81/84-294 DR ORG; Bacteria; Actinobacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces sp. KPB2; #=GS D6EME5/79-290 AC D6EME5 #=GS D6EME5/79-290 OS Streptomyces lividans TK24 #=GS D6EME5/79-290 DE Uncharacterized protein #=GS D6EME5/79-290 DR ORG; Bacteria; Actinobacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces lividans; #=GS A0A3E0GJ51/79-290 AC A0A3E0GJ51 #=GS A0A3E0GJ51/79-290 OS Streptomyces sp. 2221.1 #=GS A0A3E0GJ51/79-290 DE Membrane associated rhomboid family serine protease #=GS A0A3E0GJ51/79-290 DR ORG; Bacteria; Actinobacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces sp. 2221.1; #=GS A0A397QSJ9/79-290 AC A0A397QSJ9 #=GS A0A397QSJ9/79-290 OS Streptomyces sp. 19 #=GS A0A397QSJ9/79-290 DE Membrane associated rhomboid family serine protease #=GS A0A397QSJ9/79-290 DR ORG; Bacteria; Actinobacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces sp. 19; #=GS A0A1H2C2F0/79-290 AC A0A1H2C2F0 #=GS A0A1H2C2F0/79-290 OS Streptomyces sp. 2114.2 #=GS A0A1H2C2F0/79-290 DE Membrane associated serine protease, rhomboid family #=GS A0A1H2C2F0/79-290 DR ORG; Bacteria; Actinobacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces sp. 2114.2; #=GS G0TMC4/31-206 AC G0TMC4 #=GS G0TMC4/31-206 OS Mycobacterium canettii CIPT 140010059 #=GS G0TMC4/31-206 DE Putative conserved integral membrane protein #=GS G0TMC4/31-206 DR ORG; Bacteria; Actinobacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex; Mycobacterium canettii; #=GS A0A0H3M9T3/31-206 AC A0A0H3M9T3 #=GS A0A0H3M9T3/31-206 OS Mycobacterium tuberculosis variant bovis BCG str. Pasteur 1173P2 #=GS A0A0H3M9T3/31-206 DE Probable conserved integral membrane protein #=GS A0A0H3M9T3/31-206 DR ORG; Bacteria; Actinobacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex; Mycobacterium tuberculosis; #=GS R4M477/31-206 AC R4M477 #=GS R4M477/31-206 OS Mycobacterium tuberculosis CAS/NITR204 #=GS R4M477/31-206 DE Uncharacterized protein #=GS R4M477/31-206 DR ORG; Bacteria; Actinobacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex; Mycobacterium tuberculosis; #=GS A5TYI4/31-206 AC A5TYI4 #=GS A5TYI4/31-206 OS Mycobacterium tuberculosis H37Ra #=GS A5TYI4/31-206 DE Rhomboid family protein #=GS A5TYI4/31-206 DR ORG; Bacteria; Actinobacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex; Mycobacterium tuberculosis; #=GS A0A328H1L2/31-206 AC A0A328H1L2 #=GS A0A328H1L2/31-206 OS Mycobacterium tuberculosis variant pinnipedii #=GS A0A328H1L2/31-206 DE Rhomboid family intramembrane serine protease #=GS A0A328H1L2/31-206 DR ORG; Bacteria; Actinobacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex; Mycobacterium tuberculosis; #=GS A0A045JW70/31-206 AC A0A045JW70 #=GS A0A045JW70/31-206 OS Mycobacterium tuberculosis #=GS A0A045JW70/31-206 DE Rhomboid family intramembrane serine protease #=GS A0A045JW70/31-206 DR ORG; Bacteria; Actinobacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex; Mycobacterium tuberculosis; #=GS A0A0U0R5T6/66-242 AC A0A0U0R5T6 #=GS A0A0U0R5T6/66-242 OS Mycobacterium tuberculosis #=GS A0A0U0R5T6/66-242 DE Rhomboid family protein #=GS A0A0U0R5T6/66-242 DR ORG; Bacteria; Actinobacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex; Mycobacterium tuberculosis; #=GF SQ 14 Q9XA09/79-290 --VAADPHLVTKILIGINVAVFIAVQALPSSFLSDMVLIGRWPPAPFVPTEGVAEGEWYRLVTTMFTHEEIWHIGFNMISLWFLGGPLEAALGRARYLALYLVSGLAGSVLAYLLASPTTATLGASGAIFGLFGATAALVRRLNADMRPVVILLVISLIFTFTRGNISWQAHVGGLVAGAVIGYAMLHAPRERRTLVQYGTCALVLLVVVGLTL O53632/31-206 RQRSATP-VVTYTLISLNALVFV-MQVTVMGLERQLAL---WPPA-------VASGQTYRLVTSAFLHYGAMHLLLNMWALYVVGPPLEMWLGRLRFGALYAVSALGGSVLVYLIAPLNTATAGASGAVFGLFGATFMVARRLHLDVRWVVALIVINLAFTFLAPAISWQGHVGGLVTGALVAATYVY-------------------------- A0A3Q8VU81/84-294 --VAADPHLLTKILIGINVAVFIAVQALPSSFLSDLVLIGRWPPAPFVPTEGVAEGEWYRLVTTMFTHEEIWHIGFNMISLWFLGAPLEAALGRARYLALYLVSGLAGSALTYLLAAPTTATLGASGAVFGLFGATAALVRRLNADMRPVVILLVINLIFTFTWANIAWQAHIGGLVAGGVIGFAMLHAPRERRTLVQYGTCALVLVAVVGLT- D6EME5/79-290 --VAADPHLVTKILIGINVAVFIAVQALPSSFLSDMVLIGRWPPAPFVPTEGVAEGEWYRLVTTMFTHEEIWHIGFNMISLWFLGGPLEAALGRARYLALYLVSGLAGSVLAYLLASPTTATLGASGAIFGLFGATAALVRRLNADMRPVVILLVISLIFTFTRGNISWQAHVGGLVAGAVIGYAMLHAPRERRTLVQYGTCALVLLVVVGLTL A0A3E0GJ51/79-290 --VAADPHLVTKILIGINVAVFIAVQALPSSFLSDMVLIGRWPPAPFVPTEGVAEGEWYRLVTTMFTHEEIWHIGFNMISLWFLGGPLEAALGRARYLALYLVSGLAGSVLAYLLASPTTATLGASGAIFGLFGATAALVRRLNADMRPVVILLVISLIFTFTRGNISWQAHVGGLVAGAVIGYAMLHAPRERRTLVQYGTCALVLLVVVGLTL A0A397QSJ9/79-290 --VAADPHLVTKILIGINVAVFIAVQALPSSFLSDMVLIGRWPPAPFVPTEGVAEGEWYRLVTTMFTHEEIWHIGFNMISLWFLGGPLEAALGRARYLALYLVSGLAGSVLAYLLASPTTATLGASGAIFGLFGATAALVRRLNADMRPVVILLVISLIFTFTRGNISWQAHVGGLVAGAVIGYAMLHAPRERRTLVQYGTCALVLLVVVGLTL A0A1H2C2F0/79-290 --VAADPHLVTKILIGINVAVFIAVQALPSSFLSDMVLIGRWPPAPFVPTEGVAEGEWYRLVTTMFTHEEIWHIGFNMISLWFLGGPLEAALGRARYLALYLVSGLAGSVLAYLLASPTTATLGASGAIFGLFGATAALVRRLNADMRPVVILLVISLIFTFTRGNISWQAHVGGLVAGAVIGYAMLHAPRERRTLVQYGTCALVLLVVVGLTL G0TMC4/31-206 RQRSATP-VVTYTLISLNALVFV-MQVTVMGLERQLAL---WPPA-------VASGQTYRLVTSAFLHYGAMHLLLNMWALYVVGPPLEMWLGRLRFGALYAVSALGGSVLVYLIAPLNTATAGASGAVFGLFGATFMVARRLHLDVRWVVALIVINLAFTFLAPAISWQGHVGGLVTGALVAATYVY-------------------------- A0A0H3M9T3/31-206 RQRSATP-VVTYTLISLNALVFV-MQVTVMGLERQLAL---WPPA-------VASGQTYRLVTSAFLHYGAMHLLLNMWALYVVGPPLEMWLGRLRFGALYAVSALGGSVLVYLIAPLNTATAGASGAVFGLFGATFMVARRLHLDVRWVVALIVINLAFTFLAPAISWQGHVGGLVTGALVAATYVY-------------------------- R4M477/31-206 RQRSATP-VVTYTLISLNALVFV-MQVTVMGLERQLAL---WPPA-------VASGQTYRLVTSAFLHYGAMHLLLNMWALYVVGPPLEMWLGRLRFGALYAVSALGGSVLVYLIAPLNTATAGASGAVFGLFGATFMVARRLHLDVRWVVALIVINLAFTFLAPAISWQGHVGGLVTGALVAATYVY-------------------------- A5TYI4/31-206 RQRSATP-VVTYTLISLNALVFV-MQVTVMGLERQLAL---WPPA-------VASGQTYRLVTSAFLHYGAMHLLLNMWALYVVGPPLEMWLGRLRFGALYAVSALGGSVLVYLIAPLNTATAGASGAVFGLFGATFMVARRLHLDVRWVVALIVINLAFTFLAPAISWQGHVGGLVTGALVAATYVY-------------------------- A0A328H1L2/31-206 RQRSATP-VVTYTLISLNALVFV-MQVTVMGLERQLAL---WPPA-------VASGQTYRLVTSAFLHYGAMHLLLNMWALYVVGPPLEMWLGRLRFGALYAVSALGGSVLVYLIAPLNTATAGASGAVFGLFGATFMVARRLHLDVRWVVALIVINLAFTFLAPAISWQGHVGGLVTGALVAATYVY-------------------------- A0A045JW70/31-206 RQRSATP-VVTYTLISLNALVFV-MQVTVMGLERQLAL---WPPA-------VASGQTYRLVTSAFLHYGAMHLLLNMWALYVVGPPLEMWLGRLRFGALYAVSALGGSVLVYLIAPLNTATAGASGAVFGLFGATFMVARRLHLDVRWVVALIVINLAFTFLAPAISWQGHVGGLVTGALVAATYVY-------------------------- A0A0U0R5T6/66-242 RQRSATP-VVTYTLISLNALVFV-MQVTVMGLERQLAL---WPPA-------VASGQTYRLVTSAFLHYGAMHLLLNMWALYVVGPPLEMWLGRLRFGALYAVSALGGSVLVYLIAPLNTATAGASGAVFGLFGATFMVARRLHLDVRWVVALIVINLAFTFLAPAISWQGHVGGLVTGALVAATYVYA------------------------- #=GC scorecons 2246959268946996696599726965556645566922299992222222995964999996595946549646994695569599954999597499959969699895996955699959999979999999456699965969499596996959995455989969899996986764646722222222222222222211222221 #=GC scorecons_70 ____*_*_***__**_**__***_**_____*___*_*___****_______**_**_*****__*_*____**_***__*__**_***__***_**_***_**_*_****_****___***_*************__*_***__***_**_****_*_***____****_***********__*_**__________________________ #=GC scorecons_80 ____*_*__**__**__*__**___*___________*___****_______**_*__*****__*_*____*___**__*___*_***__***_**_***_**_*_****_**_*___***_*****_*******____***__*_*_**_*_**_*_***____****_******_**__________________________________ #=GC scorecons_90 ____*_*__**__**__*__**___*___________*___****_______**_*__*****__*_*____*___**__*___*_***__***_*__***_**_*_**_*_**_*___***_*****_*******____***__*_*_**_*_**_*_***____*_**_******_*___________________________________ //