# STOCKHOLM 1.0 #=GF ID 1.20.120.1630/FF/000014 #=GF DE Steroid 5-alpha reductase, putative #=GF AC 1.20.120.1630/FF/000014 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 94.947 #=GS Q20344/68-242 AC Q20344 #=GS Q20344/68-242 OS Caenorhabditis elegans #=GS Q20344/68-242 DE Uncharacterized protein #=GS Q20344/68-242 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis elegans; #=GS Q20344/68-242 DR GO; GO:0045087; #=GS Q23431/78-252 AC Q23431 #=GS Q23431/78-252 OS Caenorhabditis elegans #=GS Q23431/78-252 DE Uncharacterized protein #=GS Q23431/78-252 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis elegans; #=GS Q19605/72-242 AC Q19605 #=GS Q19605/72-242 OS Caenorhabditis elegans #=GS Q19605/72-242 DE Uncharacterized protein #=GS Q19605/72-242 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis elegans; #=GS T1G4L2/80-260 AC T1G4L2 #=GS T1G4L2/80-260 OS Helobdella robusta #=GS T1G4L2/80-260 DE Uncharacterized protein #=GS T1G4L2/80-260 DR ORG; Eukaryota; Metazoa; Annelida; Clitellata; Hirudinea; Hirudinida; Glossiphoniiformes; Glossiphoniidae; Helobdella; Helobdella robusta; #=GS W4YR08/7-167 AC W4YR08 #=GS W4YR08/7-167 OS Strongylocentrotus purpuratus #=GS W4YR08/7-167 DE Uncharacterized protein #=GS W4YR08/7-167 DR ORG; Eukaryota; Metazoa; Echinodermata; Echinozoa; Echinoidea; Euechinoidea; Echinacea; Echinoida; Strongylocentrotidae; Strongylocentrotus; Strongylocentrotus purpuratus; #=GS W4Z743/140-296 AC W4Z743 #=GS W4Z743/140-296 OS Strongylocentrotus purpuratus #=GS W4Z743/140-296 DE Uncharacterized protein #=GS W4Z743/140-296 DR ORG; Eukaryota; Metazoa; Echinodermata; Echinozoa; Echinoidea; Euechinoidea; Echinacea; Echinoida; Strongylocentrotidae; Strongylocentrotus; Strongylocentrotus purpuratus; #=GS A0BR98/74-244 AC A0BR98 #=GS A0BR98/74-244 OS Paramecium tetraurelia #=GS A0BR98/74-244 DE Uncharacterized protein #=GS A0BR98/74-244 DR ORG; Eukaryota; Ciliophora; Intramacronucleata; Oligohymenophorea; Peniculida; Parameciidae; Paramecium; Paramecium tetraurelia; #=GS B8CE08/2-180 AC B8CE08 #=GS B8CE08/2-180 OS Thalassiosira pseudonana #=GS B8CE08/2-180 DE 3-oxo-5-alpha-steroid 4-dehydrogenase 1-like protein #=GS B8CE08/2-180 DR ORG; Eukaryota; Bacillariophyta; Coscinodiscophyceae; Thalassiosirophycidae; Thalassiosirales; Thalassiosiraceae; Thalassiosira; Thalassiosira pseudonana; #=GS H3H5A8/82-260 AC H3H5A8 #=GS H3H5A8/82-260 OS Phytophthora ramorum #=GS H3H5A8/82-260 DE Uncharacterized protein #=GS H3H5A8/82-260 DR ORG; Eukaryota; Oomycetes; Peronosporales; Peronosporaceae; Phytophthora; Phytophthora ramorum; #=GS A2DKX3/58-240 AC A2DKX3 #=GS A2DKX3/58-240 OS Trichomonas vaginalis #=GS A2DKX3/58-240 DE 3-oxo-5-alpha-steroid 4-dehydrogenase family protein #=GS A2DKX3/58-240 DR ORG; Eukaryota; Trichomonadida; Trichomonadidae; Trichomonas; Trichomonas vaginalis; #=GS N9TQL3/69-251 AC N9TQL3 #=GS N9TQL3/69-251 OS Entamoeba histolytica HM-1:IMSS-A #=GS N9TQL3/69-251 DE Steroid 5-alpha reductase, putative #=GS N9TQL3/69-251 DR ORG; Eukaryota; Entamoebidae; Entamoeba; Entamoeba histolytica; #=GS F6R1K9/73-257 AC F6R1K9 #=GS F6R1K9/73-257 OS Ciona intestinalis #=GS F6R1K9/73-257 DE 3-oxo-5-alpha-steroid 4-dehydrogenase 1-like #=GS F6R1K9/73-257 DR ORG; Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Enterogona; Phlebobranchia; Cionidae; Ciona; Ciona intestinalis; #=GS K2HHI3/71-251 AC K2HHI3 #=GS K2HHI3/71-251 OS Entamoeba nuttalli P19 #=GS K2HHI3/71-251 DE Steroid 5-alpha reductase, putative #=GS K2HHI3/71-251 DR ORG; Eukaryota; Entamoebidae; Entamoeba; Entamoeba nuttalli; #=GS F6U0E0/7-142 AC F6U0E0 #=GS F6U0E0/7-142 OS Ornithorhynchus anatinus #=GS F6U0E0/7-142 DE Uncharacterized protein #=GS F6U0E0/7-142 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Monotremata; Ornithorhynchidae; Ornithorhynchus; Ornithorhynchus anatinus; #=GS H3EW38/43-204 AC H3EW38 #=GS H3EW38/43-204 OS Pristionchus pacificus #=GS H3EW38/43-204 DE Uncharacterized protein #=GS H3EW38/43-204 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Diplogasteromorpha; Diplogasteroidea; Neodiplogasteridae; Pristionchus; Pristionchus pacificus; #=GS A8XFC5/76-252 AC A8XFC5 #=GS A8XFC5/76-252 OS Caenorhabditis briggsae #=GS A8XFC5/76-252 DE Protein CBG12401 #=GS A8XFC5/76-252 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis briggsae; #=GS M3SDF2/69-251 AC M3SDF2 #=GS M3SDF2/69-251 OS Entamoeba histolytica HM-1:IMSS-B #=GS M3SDF2/69-251 DE Steroid 5-alpha reductase, putative #=GS M3SDF2/69-251 DR ORG; Eukaryota; Entamoebidae; Entamoeba; Entamoeba histolytica; #=GS M2R3Z5/69-251 AC M2R3Z5 #=GS M2R3Z5/69-251 OS Entamoeba histolytica KU27 #=GS M2R3Z5/69-251 DE Steroid 5 alpha reductase, putative #=GS M2R3Z5/69-251 DR ORG; Eukaryota; Entamoebidae; Entamoeba; Entamoeba histolytica; #=GS C4LVC4/69-251 AC C4LVC4 #=GS C4LVC4/69-251 OS Entamoeba histolytica #=GS C4LVC4/69-251 DE Steroid 5-alpha reductase putative #=GS C4LVC4/69-251 DR ORG; Eukaryota; Entamoebidae; Entamoeba; Entamoeba histolytica; #=GS M7XCZ5/69-251 AC M7XCZ5 #=GS M7XCZ5/69-251 OS Entamoeba histolytica HM-3:IMSS #=GS M7XCZ5/69-251 DE Steroid 5-alpha reductase, putative #=GS M7XCZ5/69-251 DR ORG; Eukaryota; Entamoebidae; Entamoeba; Entamoeba histolytica; #=GF SQ 20 Q20344/68-242 -----SSTGRILNCIFLVHYFYRALIYPFRIR--STTKSPLLIVAAAVAFCTYNGTLQGVW------NSYYQ---LEEELTYRHLIGSILYFSGMFINHKSDNILMTLRK-PGET--------GYKIPTGFLYEYISCPNYFGEIMEWIGYAILG-WNLPALAFAIFTFANIGPRAIAHHNWYKEKF-PKYPPTRR-ALIPYI Q23431/78-252 ---------SFLTCLMTFHYAYRSFVYPFIIN--SDNQSPVKIVIMAFGFSVLNGFIQGTW------NAFYQPEFDTLHPKFFVFLGAWLFVIGFITHCVSDLHLITLRN-DYLN--------SYSIPRGHYFEYISCPNYFGECLQWIGYALAA-RSFPAIAFAFFIVCNLAPRAMSHHKWYQKMFGEQYPRDRH-ALVPGV Q19605/72-242 ---------YELNAAFLFHYFFRALIYPCRIR--STTKSPVAIVAAATFFCAYNGFLQGYW------NAFYQ---PEEPWTTRKLVGSLMYCTGMYINHKSDTILRELRA-DGGT--------GYKIPTGFLYEYISCPNYAGEIMEWIGYSILA-WNLPALAFAIFTIANIGPRAVAHHKWYKETF-PGYPPNRR-ILIPRI T1G4L2/80-260 --NQVKFTNLFLLSVFALHYFNRSMVYPFKTG--SVNKIPIYITLLAFTFCCYNGYLQSKYLM----NCHYD---SDYMYSFNFIIGMSLFFIGMYLNIKSDSLMSDARKLRGPG--------TYVIPKGGLYEYVSCANYFSEIIEWVGFAIAC-WSFPAFAFALYSISYMVPRAKQNHLWYLEHF-KPYPKDRR-ILFPYI W4YR08/7-167 ----------------------RGFIHPCIMK-YSKAKVPLWITVAGIVPNSIFSFVNADWAG----SAKYS---DNYYYDPRFIIGVALYVIGFIINRWADWKLRSLRS-SGGG--------GYYIPRGGLFELVSCPNYLGELIEWFGWALAN-WSAAGLVWWLFGCSTFIPRSRDNHQWYKNKF-KEYPTNRK-ALIPFI W4Z743/140-296 -------VNVVFLSLFMAHYFHRGFIHPCIMK-YSKAKVPLWITVAGIIPNSIFSFVNADWAG----SAKYS---DNYYYDPRFIIGVVLYVIGFIINRWADWKLRNLRS-SGGG--------GYYIPRGGLFDLVSCPNYLGELIEWFGWALAN-WSAAGLVWWLFGCSTFIPRSRDNHQW--------------------- A0BR98/74-244 ------------ILLFVTHYFNRVIIYPLRLS-PLARPIPVEVVASAILFTTCNGYIQITTHL----NRDLQ---LYLPDYLRILVGILIFIYGMTSNIKCDNILRGLKK-ENSN--------EYKIPYGNLFELVSSGHYLGEIIEWFGYFLVS-GQWSGFLFFFSTLSILSARAVSTHKWYKNKF-DNYPKNRK-AIIPFI B8CE08/2-180 ---------ILLLSLFAMHYINRAIVYPLRMN-PNCQPVPLVVTLSAMMVTTLNGYLQSFYLV----NVEKE--------NLQCWLGILIFFIGMGVNIHSDGVLRNLRR-YGPSENKQQQQRTYYIPQSPLFAYISCPNFFGEILEWFGFSMASQFSLPSVAFFLYTASNLIPRGIAHHEWYLIKF-EDYPKERRWAVVPFI H3H5A8/82-260 ----------IAASLWECHYVYRSYVYPFLIRTNKDKGMPLTVMLSGDFYNMINAYVNARYLSQ-FGDYRYN--EDEMLARPSFYAGIALFVFGLSMNIYSDQVLINLRK-SGES--------GYKIPHGGLFEYVSSPNYLSELLEWAGWAMLT-QSPAGLSFVVYTATNLVPRALSNHRWYQDKFREEYPASRR-AIIPFL A2DKX3/58-240 ---RFKLIYLTFFIIFQIHYFQRSFIFPFLIK--GKSYMPILIMVMGATFNVCNGYIQGCWLFYTSPEGYYT---NEWFYTPQFIIGTLIFFTGMFINIHSDHVIRNLRK-PGDT--------KHYLPNKGMYRFVTSANYLGEIIEWFGYFILT-LSPAALVFVWFTFANLVPRAHKIYDRYLKEF-GKPVLEKK-RIFPFI N9TQL3/69-251 --SVDEIVPIISLILFVIHYFRRSIIFPLRMS--KGGKMPIIIMLMGMVFNLCNCYVQAGWLFL-YHPPHYY---LGWFNTPQCYFGVLVFFVGMAINVHSDEIIRNLRK-EGET--------EHKLPQGGLFDYVTSAQYFGELVEWLGFSIFT-LSPGAIVFFLWTFANLMPRARSVHLAYRRKF-KNQVGDRK-ILIPFI F6R1K9/73-257 GVENINFSNLLIISAFAFHYFQRSFIYPMLMN-RMSTPLPLRIVFMSFTFTFINGYAISKYEAA---HVSLP---ENWINSFQFLTGMLMWASGLLINIHSDHVLRNLRK-PNEV--------GYKIPRGGAFEYVSGANFSGEIFEWFGLLIASNFHFPLICFSLSTSLTIGTRALFHHKFYLSKF-EDYPKNRK-AVIPFV K2HHI3/71-251 ----DEIVPKISLILFVIHYFRRSIIFPLRMS--KGGKMPIIIMLMGMVFNLCNCYAQAGWLFL-YHPPYYY---LGWFNTPQCYFGVLIFFVGMAINVHSDEIIRNLRK-EGET--------EHKLPQGGLFDYVTSAQYFGELVEWLGFSIFT-LSPGAIVFFLWTFANLMPRARSIHFAYRRKF-KNQVGERK-ILIPFI F6U0E0/7-142 ---------------------------------TKGRPFPVRVTISAALFCTINGLLQGYYLTY---CAEYP---DDWYTDIRFVAGIVMFFLGMGVNIHSDHLLRQLRK-PGEI--------TYKIPQGGMFAYVSGANFLGEIVEWMGFALAT-WSLPALAFAFFSLCFLGNRAYHHHSKFLR------------------ H3EW38/43-204 ----------------------NARSIPARWG-WLIQEAPSFLLPAASFWEAPNLGCKGFY------HAWYYTFEPGHFRQPISILGFVLFFGGMAINLHSDEILRNLRK-EGET--------EYKIPRGGMFEYVSGANFFGEIIEWFGYFLVA-RSLPAAAFSFFTFANIGPRAIQHHQWYKEKF-DNYPRRRK-ALIPFI A8XFC5/76-252 -------YGKFLTCVFLFYYAYRTFAYPLLIR--SKNETPFEIVLMKFLFCIFNGFIQGSW------NAYYQPEIDKFHPRFFVFFGIWLFVIGFIIHCISDLHLISFRY-NLPND-------TYSIPRGHLFEYISCPNYFGECLQWIGYAIST-RSFPAIAFAFFVVCNIAPRAASHHECYKKKFGAQYPNDRM-ALLPG- M3SDF2/69-251 --SVDEIVPIISLILFVIHYFRRSIIFPLRMS--KGGKMPIIIMLMGMVFNLCNCYVQAGWLFL-YHPPHYY---LGWFNTPQCYFGVLVFFVGMAINVHSDEIIRNLRK-EGET--------EHKLPQGGLFDYVTSAQYFGELVEWLGFSIFT-LSPGAIVFFLWTFANLMPRARSVHLAYRRKF-KNQVGDRK-ILIPFI M2R3Z5/69-251 --SVDEIVPIISLILFVIHYFRRSIIFPLRMS--KGGKMPIIIMLMGMVFNLCNCYVQAGWLFL-YHPPHYY---LGWFNTPQCYFGVLVFFVGMAINVHSDEIIRNLRK-EGET--------EHKLPQGGLFDYVTSAQYFGELVEWLGFSIFT-LSPGAIVFFLWTFANLMPRARSVHLAYRRKF-KNQVGDRK-ILIPFI C4LVC4/69-251 --SVDEIVPIISLILFVIHYFRRSIIFPLRMS--KGGKMPIIIMLMGMVFNLCNCYVQAGWLFL-YHPPHYY---LGWFNTPQCYFGVLVFFVGMAINVHSDEIIRNLRK-EGET--------EHKLPQGGLFDYVTSAQYFGELVEWLGFSIFT-LSPGAIVFFLWTFANLMPRARSVHLAYRRKF-KNQVGDRK-ILIPFI M7XCZ5/69-251 --SVDEIVPIISLILFVIHYFRRSIIFPLRMS--KGGKMPIIIMLMGMVFNLCNCYVQAGWLFL-YHPPHYY---LGWFNTPQCYFGVLVFFVGMAINVHSDEIIRNLRK-EGET--------EHKLPQGGLFDYVTSAQYFGELVEWLGFSIFT-LSPGAIVFFLWTFANLMPRARSVHLAYRRKF-KNQVGDRK-ILIPFI #=GC scorecons 00000001112222352256327435573343004334495274445336433745565252100004436300033332344344944575496367447924655785036440000000047469475675676556757955894954644036346557354534553797344834733460334423640455645 #=GC scorecons_70 ______________________*____*___________*__*__________*________________*_______________*___*__*__**__**__*__**_______________*_**_*_**_***__**_**__**_*_______*_____*_________***___*__*___*_______*_____*__ #=GC scorecons_80 ______________________*____*___________*__*__________*________________________________*___*__*___*__**_____**_______________*__*_*__*__*____*_**__**_*_____________*__________**___*__*____________________ #=GC scorecons_90 _______________________________________*______________________________________________*______*_______*______*__________________*_______________*___*_*________________________*____*_______________________ //