# STOCKHOLM 1.0 #=GF ID 1.10.630.10/FF/000147 #=GF DE (S)-stylopine synthase 1 #=GF AC 1.10.630.10/FF/000147 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 63.346 #=GS B1NF19/42-504 AC B1NF19 #=GS B1NF19/42-504 OS Argemone mexicana #=GS B1NF19/42-504 DE Trifunctional (S)-stylopine synthase/(S)-nandinine synthase/(S)-canadine synthase #=GS B1NF19/42-504 DR ORG; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Ranunculales; Papaveraceae; Papaveroideae; Argemone; Argemone mexicana; #=GS B1NF19/42-504 DR GO; GO:0033075; GO:0047052; GO:0047056; GO:0102632; #=GS B1NF19/42-504 DR EC; 1.14.19.64; 1.14.19.68; 1.14.19.73; #=GS Q948Y1/27-486 AC Q948Y1 #=GS Q948Y1/27-486 OS Coptis japonica #=GS Q948Y1/27-486 DE (S)-canadine synthase #=GS Q948Y1/27-486 DR ORG; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Ranunculales; Ranunculaceae; Coptidoideae; Coptis; Coptis japonica; #=GS Q948Y1/27-486 DR GO; GO:0033075; GO:0043231; GO:0047056; #=GS Q948Y1/27-486 DR EC; 1.14.19.68; #=GS B1NF18/41-504 AC B1NF18 #=GS B1NF18/41-504 OS Papaver somniferum #=GS B1NF18/41-504 DE Salutaridine synthase #=GS B1NF18/41-504 DR ORG; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Ranunculales; Papaveraceae; Papaveroideae; Papaver; Papaver somniferum; #=GS B1NF18/41-504 DR GO; GO:0047055; GO:0097295; #=GS B1NF18/41-504 DR EC; 1.14.19.67; #=GS B5UAQ8/28-490 AC B5UAQ8 #=GS B5UAQ8/28-490 OS Eschscholzia californica #=GS B5UAQ8/28-490 DE Cheilanthifoline synthase #=GS B5UAQ8/28-490 DR ORG; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Ranunculales; Papaveraceae; Eschscholzioideae; Eschscholzia; Eschscholzia californica; #=GS B5UAQ8/28-490 DR GO; GO:0033075; GO:0047053; #=GS B5UAQ8/28-490 DR EC; 1.14.19.65; #=GS Q50LH3/32-495 AC Q50LH3 #=GS Q50LH3/32-495 OS Eschscholzia californica #=GS Q50LH3/32-495 DE (S)-stylopine synthase 1 #=GS Q50LH3/32-495 DR ORG; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Ranunculales; Papaveraceae; Eschscholzioideae; Eschscholzia; Eschscholzia californica; #=GS Q50LH3/32-495 DR GO; GO:0033075; GO:0047052; #=GS Q50LH3/32-495 DR EC; 1.14.19.64; #=GS Q50LH4/33-495 AC Q50LH4 #=GS Q50LH4/33-495 OS Eschscholzia californica #=GS Q50LH4/33-495 DE Trifunctional (S)-stylopine synthase 2/(S)-nandinine synthase/(S)-canadine synthase #=GS Q50LH4/33-495 DR ORG; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Ranunculales; Papaveraceae; Eschscholzioideae; Eschscholzia; Eschscholzia californica; #=GS Q50LH4/33-495 DR GO; GO:0033075; GO:0047052; GO:0102632; #=GS Q50LH4/33-495 DR EC; 1.14.19.64; 1.14.19.68; 1.14.19.73; #=GS B1NF20/32-494 AC B1NF20 #=GS B1NF20/32-494 OS Argemone mexicana #=GS B1NF20/32-494 DE Cheilanthifoline synthase #=GS B1NF20/32-494 DR ORG; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Ranunculales; Papaveraceae; Papaveroideae; Argemone; Argemone mexicana; #=GS B1NF20/32-494 DR GO; GO:0033075; GO:0047053; #=GS B1NF20/32-494 DR EC; 1.14.19.65; #=GF SQ 7 B1NF19/42-504 ---SSSKMVWPTGPKTLPIIGNMNILGGTA-LHVVLHNLAKTYGNVMTIWIGSWRPVIVVSDIDRAWEVLVNKSSDYSARDMPEITKLATADWKTISSSDSGPFWTNLRKGLQNVALSPQNLSSQSKFQERDIIKTIQNLKEEAKMNNGIVKPLDHLKKAMVRLISRLIYGQDFDNDEYVEEMHHTIEELIRVSGYARLAEAFYYAKYLPSHKKAVREVLQANQRVQNLVRPLLSLNSPTNTYLHFLRSQNYEDEVIIFAIFEAYLLGVDSTSSTTAWALAYLIREPNVQEKLYEELKNFTNDNDRKMVKFEDLNKLQYLQAVVKETMRMKPIAPLAIPHKACRETSLMGRKVNQGTRVMVNIYALHHNQNVWKEPYKFNPERFLQ---KNQDGVDGKAMEQSLLPFSAGMRICAGMELGKLQFSFALANLVNAFKWSCVSDGVFPDMSDQLGFVLLMKTPLEAGIVPRM---- Q948Y1/27-486 SSSSLPQMKWPSGPRKLPIIGNLHQLGDDV-LHVALAKLAKVHGSVMTIWIGSWRPVIVISDIEKAWEVLVNKSADYGARDMPEITKIASASWHTISTSDAGSFWQNVRKGLQSGAMGPLNVAAQNQYQERDMKRLIKAMSDEAANNNGIVKPLDHIKKNTVRLLTRLIFGQAFDDNKFIESMHYEIEDIIRISGYARLAEAFYYAKYLPSHKKAEREAFLVKCRVEELVRPLLSSKPPTNSYLYFLLSQNFEEEVIIFCIFELYLLGVDSTSSTTTWALAYLIREQGAQEKLYQDIRMTL--GDVDLVKIEDVNKLKYLQGVVKETMRMKPIAPLAIPHKTAKETTLMGTKVAKGTRIMVNLYALHHNQNIWPDPYKFMPERFLE---GETGTAYNKAMEQSFLPFSAGMRICAGMDLGKLQFAFALANLVNAFKWSCVEEGKLPDMGEELSFVLLMKTPLEARI-------- B1NF18/41-504 -------TEWPAGPKTLPIIGNLHQLGGGVPLQVALANLAKVYGGAFTIWIGSWVPMIVISDIDNAREVLVNKSADYSARDVPDILKIITANGKNIADCDSGPFWHNLKKGLQS-CINPSNVMSLSRLQEKDMQNLIKSMQERASQHNGIIKPLDHAKEASMRLLSRVIFGHDFSNEDLVIGVKDALDEMVRISGLASLADAFKIAKYLPSQRKNIRDMYATRDRVYNLIQPHIVPNLPANSFLYFLTSQDYSDEIIYSMVLEIFGLGVDSTAATAVWALSFLVGEQEIQEKLYREINNRT--GGQRPVKVVDLKELPYLQAVMKETLRMKPIAPLAVPHVAAKDTTFKGRRIVKGTKVMVNLYAIHHDPNVFPAPYKFMPERFLKDVNSDGRFGDINTMESSLIPFGAGMRICGGVELAKQMVAFALASMVNEFKWDCVSEGKLPDLSEAISFILYMKNPLEAKITPRTKPFR B5UAQ8/28-490 ----ISTMEWPKGPKKLPIIGNLHQLGGEA-FHVVLANLAKIHGTVMTIWVGAWRPMIVISDIDKAWEVLVNKSSDYAGRDFPEITKIISANWKNISCSDSGPFWQNLRKGLQGGALAPLNVISQYQLQERDMKNLITSMQEKASKNNGILKPLDYLKEETIRLLSRLIFGQSFNDENFVKGVHLALDDLVRISGYASLADAFKFCENLPSHKKSIREVHEVNERVVNLVKPYLVKNPPTNTYLYFLNSQKFSDEVIISAVLEVYDLGVDSTASTAVWALTFLVREPRVQEKLYKEIIDLT--GGERSVKVEDVSKLPYLQAVMKETMRMKPIAPMAIPHKTSRDTSLMGKKVNKGTSIMVNLYAIHHNPKVFPEPYKFIPERFLQ--GQESKYGDIKEMEQSLLPFSAGMRICAGMELGKLQYGFSLASLVEAFKWTCAVDGKLPDLSEDHCFILLMKNPLEARITPRTQL-- Q50LH3/32-495 --RKSSKMVWPAGPKTLPIIGNMHLLGGTA-LQVVLHNLAKVHGSVMTIWIGSWRPVIVVSDIERAWEVLVNKSSDYSARDMPDITKIISADWKTISTSDSGPHWTNLRKGLQNVALSPHNLAAQFQFQEKDMTKMIQTLEEEARNNNGIVKPLDHMKKATLRLISRLVFGQDFNNDKYVDDMHLAIEELIRVSGYARLAEAFYYAKYLPSHKKAVREVEEAQRRVQNLVSPFLSLNPPTNTYLHFLRSQKYDDEVIIFAIFEAYLLGVDSTSLTTAWALAFLIREPNVQEKLYQELESFASKNDRRILKVEDINKLQYLQAVIKETMRMKPIAPLAIPHKACRDTSLMGKKIDKGTRVMVNIFALHHNKNVFNDPFKFMPERFMK---VDSQDANGKAMEQSLLPFSAGMRICAGMELGKLQFSFALANLAYAFKWSCVADGVLPDMSDQLGFVLLMKTPLEARINRRN---- Q50LH4/33-495 ---KSPNMAWPEGPKTLPIIGNMHLLGGTA-LQVVLYNLAKVHGRVMTIWIGSWRPVIVVSDIEQAWEVLVNKSSDYSARDMPDITKIVTADWRTISTSDSGPHWSNLRKGLQNIAISPNNLAAQFQFQEKDIIKMIQILEQEAKDNNGIVKPLDHLKKATIRLISRLVFGRDFEEDKYVEDMHHAIEELIRISGYARLAEAFYYAKYLPSHRKAVRYVEELKQIVKNLIRPFLSVNPPTNTYLHFLRSQNYDEEVVIFAIFETYLLGVDSTSSTTAWALAYLVREPSVQDRLHQELDHFAKQNDRKILKVEDMNKLQYLQAVIKETMRMKPIAPLAIPHKACKDTSLMGNKINKGTRVMVNLYALHHNKNVFNDPFKFMPERFLK---VDNQDAKGKAMEQSLLPFSAGMRICAGMELGKLQFSFALANLIFAFKWSCVDDGVLPDMSDELGFVLLMKTPLKARINPRN---- B1NF20/32-494 -----STMEWPVGPKKLPIIGNLHQLGGDV-FHVVLANLAKVYGSVFTIWVGSWRPMIIVSDIDKAWEVLVNKSSDYSARDMPDITKIISANWKNISCSDSGPFWHNLRKGLQGVALTPLNVASQYHLQERDMKNLINSMYKDASRKNGILKPLDYLKEETVRLLSRLIFGQDFQDEKLVVGMHHALDDLVRISGYASLADAFKFCENLPSHKKSIREVHEVKKRVENLIRPHIVSNPPTNTYLYFLKTQDFNEDIIISAILEVYDLGVDSTASTTVWALTFLVREQEIQEKLYREIVNVT--GGKRSVKVEDVNKMPYLQAVMKETMRMKPIAPMAIPHKTSKDTSLMGKKINKGSVIMVNLYAIHHNPKVFPEPYKFMPERFLKDVNSDESLGNIKTMESSLLAFSAGMRICAGMELGKLQLAFGLASLVHEFKWSCSVDGKLPDLSEDHCFILLMKNPLEAKITCRIH--- #=GC scorecons 000113263993997599999967499745066969479996693759997979696986999659699999996996799596969755956659737979769397799994265493964563559969735594463559435999599997495455996797789659455557346735666669799695996994556599977955955334436927965946537597967969937947468786457694739999995596599957966953598898576233500553536966955774999795999799999997979966467967694764797469996896997467545979969999750002633244375995977797999999797797966559699576359995953794799676444969699599795933620000 #=GC scorecons_70 _______*_**_***_********_***___***_*_*******_*_*********_*******_*********_**_***_******__*_**_**_*******_*******__*__*_**__*___*****___*__*___*___***_*****_*____**********_*_____*__**___**********_*****___*_******__*_______**_***_*_*__*_***_*****_**_*_*****__*_*_*_******__**_***_*****___*****_**___________*****__**_*****_*****************__***_***_**_***_*******_***_**___****_*****____________*_**_*********************__*_**_**__***_*__**_******___******_****_*________ #=GC scorecons_80 _________**_***_******_*_***_____*_*_****__*___*******_*_**_***__*_*******_**_***_*_*_**__*____*___****_*_*******_____*_*_______**_*____*______*___***_*****_*____**_******__*_____*___________****_*_**_**_____******__*________*_**__*____*_***_**_**_**_*__*_*_____*_*_******__*__***_**__*___*****_*_____________*__*___*_*****_***********_****____**_*_*_*__***__***_**_***__*___****_*****______________**_*****_******_****_*____*_**_*___***_*___*_***_*____*_*_**_****_*________ #=GC scorecons_90 _________**_**__******___**______*_*__***__*___***_*_*_*_*__***__*_*******_**__**_*_*_*___*____*___*_*__*_*__****_____*_*_______**_*____*______*___***_****__*____**__*__**__*_________________*_**_*_**_**_____***__*__*________*__*__*______*_*__*_**__*____________*___******__*__***__*__*___*__*________________*__*_____***_*_***_*******_*_**_____*___*_____*___***_**_**_______*_**_****_______________**_*___*_******_*__*_*____*_**_____***_*___*__**______*_*_**_**_*_*________ //