# STOCKHOLM 1.0 #=GF ID 1.10.510.10/FF/000987 #=GF DE Receptor protein-tyrosine kinase #=GF AC 1.10.510.10/FF/000987 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 87.407 #=GS Q968Y9/1331-1546 AC Q968Y9 #=GS Q968Y9/1331-1546 OS Caenorhabditis elegans #=GS Q968Y9/1331-1546 DE Insulin-like receptor #=GS Q968Y9/1331-1546 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis elegans; #=GS Q968Y9/1331-1546 DR GO; GO:0000003; GO:0005009; GO:0005515; GO:0005524; GO:0005737; GO:0006606; GO:0006979; GO:0008286; GO:0008340; GO:0009411; GO:0010286; GO:0010468; GO:0010628; GO:0010629; GO:0010883; GO:0010888; GO:0017046; GO:0019901; GO:0030424; GO:0030536; GO:0031410; GO:0032435; GO:0040018; GO:0040024; GO:0040034; GO:0042169; GO:0043025; GO:0043054; GO:0044214; GO:0045887; GO:0045944; GO:0046777; GO:0051425; GO:0061065; GO:0097730; GO:1900075; GO:1900181; GO:1901031; GO:1902075; GO:1903998; GO:1905909; GO:1905910; GO:2000785; #=GS Q968Y9/1331-1546 DR EC; 2.7.10.1; #=GS A0A0K3AUA1/521-737 AC A0A0K3AUA1 #=GS A0A0K3AUA1/521-737 OS Caenorhabditis elegans #=GS A0A0K3AUA1/521-737 DE Uncharacterized protein #=GS A0A0K3AUA1/521-737 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis elegans; #=GS A0A0K3ARZ1/1255-1470 AC A0A0K3ARZ1 #=GS A0A0K3ARZ1/1255-1470 OS Caenorhabditis elegans #=GS A0A0K3ARZ1/1255-1470 DE Receptor protein-tyrosine kinase #=GS A0A0K3ARZ1/1255-1470 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis elegans; #=GS A0A0K3AXA0/1284-1499 AC A0A0K3AXA0 #=GS A0A0K3AXA0/1284-1499 OS Caenorhabditis elegans #=GS A0A0K3AXA0/1284-1499 DE Receptor protein-tyrosine kinase #=GS A0A0K3AXA0/1284-1499 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis elegans; #=GS A0A0K3AUY1/1413-1628 AC A0A0K3AUY1 #=GS A0A0K3AUY1/1413-1628 OS Caenorhabditis elegans #=GS A0A0K3AUY1/1413-1628 DE Receptor protein-tyrosine kinase #=GS A0A0K3AUY1/1413-1628 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis elegans; #=GS A9VBG8/1369-1562 AC A9VBG8 #=GS A9VBG8/1369-1562 OS Monosiga brevicollis #=GS A9VBG8/1369-1562 DE Predicted protein #=GS A9VBG8/1369-1562 DR ORG; Eukaryota; Choanoflagellida; Salpingoecidae; Monosiga; Monosiga brevicollis; #=GS G1KXB3/307-487 AC G1KXB3 #=GS G1KXB3/307-487 OS Anolis carolinensis #=GS G1KXB3/307-487 DE Tyrosine-protein kinase #=GS G1KXB3/307-487 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Lepidosauria; Squamata; Iguania; Dactyloidae; Anolis; Anolis carolinensis; #=GS C3YQM6/1137-1349 AC C3YQM6 #=GS C3YQM6/1137-1349 OS Branchiostoma floridae #=GS C3YQM6/1137-1349 DE Uncharacterized protein #=GS C3YQM6/1137-1349 DR ORG; Eukaryota; Metazoa; Chordata; Cephalochordata; Branchiostomidae; Branchiostoma; Branchiostoma floridae; #=GS A8XMN1/1321-1538 AC A8XMN1 #=GS A8XMN1/1321-1538 OS Caenorhabditis briggsae #=GS A8XMN1/1321-1538 DE Protein CBR-DAF-2 #=GS A8XMN1/1321-1538 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis briggsae; #=GS A0A2G5UNS1/1417-1634 AC A0A2G5UNS1 #=GS A0A2G5UNS1/1417-1634 OS Caenorhabditis nigoni #=GS A0A2G5UNS1/1417-1634 DE Uncharacterized protein #=GS A0A2G5UNS1/1417-1634 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis nigoni; #=GS A9USN6/296-489 AC A9USN6 #=GS A9USN6/296-489 OS Monosiga brevicollis #=GS A9USN6/296-489 DE Predicted protein #=GS A9USN6/296-489 DR ORG; Eukaryota; Choanoflagellida; Salpingoecidae; Monosiga; Monosiga brevicollis; #=GS A0A2G5UNT9/1434-1651 AC A0A2G5UNT9 #=GS A0A2G5UNT9/1434-1651 OS Caenorhabditis nigoni #=GS A0A2G5UNT9/1434-1651 DE Uncharacterized protein #=GS A0A2G5UNT9/1434-1651 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis nigoni; #=GS A0A2G5UNS5/1427-1644 AC A0A2G5UNS5 #=GS A0A2G5UNS5/1427-1644 OS Caenorhabditis nigoni #=GS A0A2G5UNS5/1427-1644 DE Uncharacterized protein #=GS A0A2G5UNS5/1427-1644 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis nigoni; #=GS C3YQL9/302-507 AC C3YQL9 #=GS C3YQL9/302-507 OS Branchiostoma floridae #=GS C3YQL9/302-507 DE Receptor protein-tyrosine kinase #=GS C3YQL9/302-507 DR ORG; Eukaryota; Metazoa; Chordata; Cephalochordata; Branchiostomidae; Branchiostoma; Branchiostoma floridae; #=GF SQ 14 Q968Y9/1331-1546 -MDLGNLRDYLRSKREDEVFNETDCN---------FFDIIPRDKFHEWAAQICDGMAYLESLKFCHRDLAARNCMINRDETVKIGDFGMARDLFY-HDYYKPSGKRMMPVRWMSPESLKDGKFDSKSDVWSFGVVLYEMVTLGAQPYIGLSNDEVLNYIGMARKVIKKPECCENYWYKVMKMCWRYSPRDRPTFLQLVHLLAAEASPEFRDLSFVLTDNQMILDDSE--- A0A0K3AUA1/521-737 -MDLGNLRDYLRSKREDEVFNETDCN---------FFDIIPRDKFHEWAAQICDGMAYLESLKFCHRDLAARNCMINRDETVKIGDFGMARDLFY-HDYYKPSGKRMMPVRWMSPESLKDGKFDSKSDVWSFGVVLYEMVTLGAQPYIGLSNDEVLNYIGMARKVIKKPECCENYWYKVMKMCWRYSPRDRPTFLQLVHLLAAEASPEFRDLSFVLTDNQMILDDSEA-- A0A0K3ARZ1/1255-1470 -MDLGNLRDYLRSKREDEVFNETDCN---------FFDIIPRDKFHEWAAQICDGMAYLESLKFCHRDLAARNCMINRDETVKIGDFGMARDLFY-HDYYKPSGKRMMPVRWMSPESLKDGKFDSKSDVWSFGVVLYEMVTLGAQPYIGLSNDEVLNYIGMARKVIKKPECCENYWYKVMKMCWRYSPRDRPTFLQLVHLLAAEASPEFRDLSFVLTDNQMILDDSE--- A0A0K3AXA0/1284-1499 -MDLGNLRDYLRSKREDEVFNETDCN---------FFDIIPRDKFHEWAAQICDGMAYLESLKFCHRDLAARNCMINRDETVKIGDFGMARDLFY-HDYYKPSGKRMMPVRWMSPESLKDGKFDSKSDVWSFGVVLYEMVTLGAQPYIGLSNDEVLNYIGMARKVIKKPECCENYWYKVMKMCWRYSPRDRPTFLQLVHLLAAEASPEFRDLSFVLTDNQMILDDSE--- A0A0K3AUY1/1413-1628 -MDLGNLRDYLRSKREDEVFNETDCN---------FFDIIPRDKFHEWAAQICDGMAYLESLKFCHRDLAARNCMINRDETVKIGDFGMARDLFY-HDYYKPSGKRMMPVRWMSPESLKDGKFDSKSDVWSFGVVLYEMVTLGAQPYIGLSNDEVLNYIGMARKVIKKPECCENYWYKVMKMCWRYSPRDRPTFLQLVHLLAAEASPEFRDLSFVLTDNQMILDDSE--- A9VBG8/1369-1562 NMANGDLLGFLRGARPPA-------------PG--QDAALTMTDLVYMAADVASGMAFLAQGNFIHRDLAARNCLVAEDMVVKVADFGLSRALNY-SDYYRKNGQALLPVRWMCPMALCEGKFTTDTDVYSFGILLYELFTLGALPYTDMSNQQVFEQVVAGYR-MEQPQGCPDVIYKIMWECWRLS--DRPSFENLEERLMNIGR---------------RLEDGDL-- G1KXB3/307-487 --RKGNLHSYLNSV---------------------AGKELTTHHLLSISCQVADGMTYLEEQHVVHRDLAARNILVGDDLACKIADFGLARLLK--DDIYSTSSNTMIPVKWTAPEAAIYQTYSPKSDVWSYGILLYEVFTYGQCPYEGMTNQETIQQITRGYR-LPRPNSCSPEIYSVMLECWKSHPEDRPSFLTLRESLFSIYK-----------------------W C3YQM6/1137-1349 --GNGDLLKFLRKSRVLEAASLTYVN-RPNFGGGRTMSTLSPVQLLRIACDVATGMDHLSSKQVIHRDLAARNVLLTDSLIAKVADFGLSRG----EGIYEQTSKKAIPFRSTALEALTRRIYTTKSDVWSFGILLWEIVTIGGTPYCGMKSRTILGRLREGYR-LPKPRNCEADMYQLMLLCWKTHPEDRPSFTDLAEQLEIMIEDKHSYM---------NVDKDDDFE A8XMN1/1321-1538 FMELGNLRDYLRAKREEEVFDENNCN---------FYNIVPREKICEWAAQICDGMAYLESLKFCHRDLAARNCMIDKTELVKIGDFGMARDLFY-HDYYKPSGKRMMPVRWMSPESLKDGKFDSKSDIWSFGVVLYELITLGAQPYIGLSNDEVLNYIGMARKVIKKPDCCSEYWYKIMKMCWRYAPRDRPTFLQLVHLLSAEASEEFKTLSFVFTENQMAMEDTEP-- A0A2G5UNS1/1417-1634 FMELGNLRDYLRAKREEEVFDENNCN---------FYNIVPREKICEWAAQICDGMAYLESLKFCHRDLAARNCMIDKTELVKIGDFGMARDLFY-HDYYKPSGKRMMPVRWMSPESLKDGKFDSKSDIWSFGVVLYELITLGAQPYIGLSNDEVLNYIGMARKVIKKPDCCSEYWYKIMKMCWRYAPRDRPTFLQLVHLLSAEASEEFKTLSFVFTENQMAMEDTEP-- A9USN6/296-489 -IPYGDVRSVLKACRSAS-------------------TAVHAHEQVYMAAQAAAGMEYLASLGFVHRDLAARNILLGRYCHIKLADFGLSRALDTESQYYVVQSRSLLPFRWMSIEALKEGKFTTQSDVWAFGVLLWEIMSMAKTPWRKNSTQEVKQLILAGER-LPPPRNCPQTLYSLMTTCWQPAPAARPTFVTLRRSLEQQGE---------------LLNPEKLKP A0A2G5UNT9/1434-1651 FMELGNLRDYLRAKREEEVFDENNCN---------FYNIVPREKICEWAAQICDGMAYLESLKFCHRDLAARNCMIDKTELVKIGDFGMARDLFY-HDYYKPSGKRMMPVRWMSPESLKDGKFDSKSDIWSFGVVLYELITLGAQPYIGLSNDEVLNYIGMARKVIKKPDCCSEYWYKIMKMCWRYAPRDRPTFLQLVHLLSAEASEEFKTLSFVFTENQMAMEDTEP-- A0A2G5UNS5/1427-1644 FMELGNLRDYLRAKREEEVFDENNCN---------FYNIVPREKICEWAAQICDGMAYLESLKFCHRDLAARNCMIDKTELVKIGDFGMARDLFY-HDYYKPSGKRMMPVRWMSPESLKDGKFDSKSDIWSFGVVLYELITLGAQPYIGLSNDEVLNYIGMARKVIKKPDCCSEYWYKIMKMCWRYAPRDRPTFLQLVHLLSAEASEEFKTLSFVFTENQMAMEDTEP-- C3YQL9/302-507 ------LLKFLRNSRVQDA--VTYVNHQPKFGG--TVSTISPVQLLRIACDVAAGMDHLSSKQVIHRDLAARNVLLTDSLIAKVADFGLSRG----EGIYEQTSKRAIPFRSTALEALARRIYTTKSDVWSFGILLWEIVTIGGTPYRGMKSRTILGRLREGYR-LPKPRNCEADLYQLMVMCWNTRPEDRPSFADLAEQIEIMIEDKHSYV---------NIDKGDDFE #=GC scorecons 03237574469743732421122123000000000323454434433375665499479464464999999994654443359669996694522045594456645596866557674455745679777897696955757449736556456544633647164694494333955934995347379969449453734344122212111111111244434100 #=GC scorecons_70 ____*_*___**__*_________________________________*_____**_**_*____********_*_______**_****_*________*____*___*_*____*_*____*__***********_*__*_*__**_*_____*___*____*____*__*____*__*__**___*_***_*__*___*_____________________________ #=GC scorecons_80 ______*___*_____________________________________*_____**__*______********_________*__***__*________*________*_*____*_*____*___*******__*_*__*_*__**_____________________*__*____*__*__**_____***_*__*___*_____________________________ #=GC scorecons_90 __________*___________________________________________**__*______********_________*__***__*________*________*_*________________*___**__*_*_______*______________________*__*____*__*__**______**_*__*_________________________________ //