# STOCKHOLM 1.0 #=GF ID 1.10.510.10/FF/000757 #=GF DE AGC family serine/threonine kinase #=GF AC 1.10.510.10/FF/000757 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 91.258 #=GS Q54C18/310-497 AC Q54C18 #=GS Q54C18/310-497 OS Dictyostelium discoideum #=GS Q54C18/310-497 DE Probable serine/threonine-protein kinase DDB_G0293276 #=GS Q54C18/310-497 DR ORG; Eukaryota; Dictyosteliales; Dictyosteliaceae; Dictyostelium; Dictyostelium discoideum; #=GS Q54C18/310-497 DR EC; 2.7.11.1; #=GS Q582V7/145-346 AC Q582V7 #=GS Q582V7/145-346 OS Trypanosoma brucei brucei TREU927 #=GS Q582V7/145-346 DE Serine/threonine-protein kinase, putative #=GS Q582V7/145-346 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; Trypanosoma brucei brucei; #=GS Q582V7/145-346 DR GO; GO:0000281; GO:0004674; GO:0005524; GO:0005737; GO:0006468; GO:0031981; GO:0097014; #=GS Q4Q9K2/129-324 AC Q4Q9K2 #=GS Q4Q9K2/129-324 OS Leishmania major #=GS Q4Q9K2/129-324 DE Putative serine/threonine-protein kinase #=GS Q4Q9K2/129-324 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania major species complex; Leishmania major; #=GS Q4Q9K2/129-324 DR GO; GO:0000281; GO:0005737; GO:0031981; GO:0097014; #=GS E9HCS8/94-284 AC E9HCS8 #=GS E9HCS8/94-284 OS Daphnia pulex #=GS E9HCS8/94-284 DE Uncharacterized protein #=GS E9HCS8/94-284 DR ORG; Eukaryota; Metazoa; Arthropoda; Crustacea; Branchiopoda; Phyllopoda; Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia; Daphnia pulex; #=GS A2EHM3/380-442_463-589 AC A2EHM3 #=GS A2EHM3/380-442_463-589 OS Trichomonas vaginalis #=GS A2EHM3/380-442_463-589 DE AGC family protein kinase #=GS A2EHM3/380-442_463-589 DR ORG; Eukaryota; Trichomonadida; Trichomonadidae; Trichomonas; Trichomonas vaginalis; #=GS F6YG11/99-301 AC F6YG11 #=GS F6YG11/99-301 OS Xenopus tropicalis #=GS F6YG11/99-301 DE Uncharacterized protein #=GS F6YG11/99-301 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana; Xenopus tropicalis; #=GS A0A0N1PC31/130-329 AC A0A0N1PC31 #=GS A0A0N1PC31/130-329 OS Leptomonas seymouri #=GS A0A0N1PC31/130-329 DE Uncharacterized protein #=GS A0A0N1PC31/130-329 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leptomonas; Leptomonas seymouri; #=GS F0ZMX4/261-452 AC F0ZMX4 #=GS F0ZMX4/261-452 OS Dictyostelium purpureum #=GS F0ZMX4/261-452 DE Uncharacterized protein #=GS F0ZMX4/261-452 DR ORG; Eukaryota; Dictyosteliales; Dictyosteliaceae; Dictyostelium; Dictyostelium purpureum; #=GS A0A1G4IEB5/145-346 AC A0A1G4IEB5 #=GS A0A1G4IEB5/145-346 OS Trypanosoma equiperdum #=GS A0A1G4IEB5/145-346 DE AGC family serine/threonine kinase, putative #=GS A0A1G4IEB5/145-346 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma equiperdum; #=GS A0A088RSK6/130-329 AC A0A088RSK6 #=GS A0A088RSK6/130-329 OS Leishmania panamensis #=GS A0A088RSK6/130-329 DE Serine/threonine-protein kinase, putative #=GS A0A088RSK6/130-329 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania guyanensis species complex; Leishmania panamensis; #=GS A0A0N0VF50/130-327 AC A0A0N0VF50 #=GS A0A0N0VF50/130-327 OS Leptomonas pyrrhocoris #=GS A0A0N0VF50/130-327 DE Putative Serine/threonine-protein kinase #=GS A0A0N0VF50/130-327 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leptomonas; Leptomonas pyrrhocoris; #=GS A0A3L6LB87/145-346 AC A0A3L6LB87 #=GS A0A3L6LB87/145-346 OS Trypanosoma brucei equiperdum #=GS A0A3L6LB87/145-346 DE AGC family serine/threonine kinase #=GS A0A3L6LB87/145-346 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; Trypanosoma brucei equiperdum; #=GS C9ZKE1/145-346 AC C9ZKE1 #=GS C9ZKE1/145-346 OS Trypanosoma brucei gambiense DAL972 #=GS C9ZKE1/145-346 DE Serine/threonine-protein kinase, putative #=GS C9ZKE1/145-346 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; Trypanosoma brucei gambiense; #=GS A0A3Q8INQ4/130-327 AC A0A3Q8INQ4 #=GS A0A3Q8INQ4/130-327 OS Leishmania donovani #=GS A0A3Q8INQ4/130-327 DE AGC family serine/threonine kinase, putative #=GS A0A3Q8INQ4/130-327 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania donovani; #=GS E9AXW8/130-327 AC E9AXW8 #=GS E9AXW8/130-327 OS Leishmania mexicana MHOM/GT/2001/U1103 #=GS E9AXW8/130-327 DE Putative serine/threonine-protein kinase (Putative protein kinase) #=GS E9AXW8/130-327 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania mexicana species complex; Leishmania mexicana; #=GS A0A3P3Z8S3/130-329 AC A0A3P3Z8S3 #=GS A0A3P3Z8S3/130-329 OS Leishmania braziliensis MHOM/BR/75/M2904 #=GS A0A3P3Z8S3/130-329 DE AGC_family_serine/threonine_kinase #=GS A0A3P3Z8S3/130-329 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania braziliensis species complex; Leishmania braziliensis; #=GS A4I1T4/130-327 AC A4I1T4 #=GS A4I1T4/130-327 OS Leishmania infantum #=GS A4I1T4/130-327 DE AGC_family_serine/threonine_kinase_-_putative #=GS A4I1T4/130-327 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania infantum; #=GS E9BHZ9/130-327 AC E9BHZ9 #=GS E9BHZ9/130-327 OS Leishmania donovani BPK282A1 #=GS E9BHZ9/130-327 DE Serine/threonine-protein kinase, putative #=GS E9BHZ9/130-327 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania donovani; #=GS A4HED7/130-329 AC A4HED7 #=GS A4HED7/130-329 OS Leishmania braziliensis #=GS A4HED7/130-329 DE Putative serine/threonine-protein kinase #=GS A4HED7/130-329 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania braziliensis species complex; Leishmania braziliensis; #=GS F7D4V7/156-346 AC F7D4V7 #=GS F7D4V7/156-346 OS Xenopus tropicalis #=GS F7D4V7/156-346 DE Uncharacterized protein #=GS F7D4V7/156-346 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana; Xenopus tropicalis; #=GS F6TET1/99-282 AC F6TET1 #=GS F6TET1/99-282 OS Xenopus tropicalis #=GS F6TET1/99-282 DE Uncharacterized protein #=GS F6TET1/99-282 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana; Xenopus tropicalis; #=GS A0A1B8Y4E3/103-277 AC A0A1B8Y4E3 #=GS A0A1B8Y4E3/103-277 OS Xenopus tropicalis #=GS A0A1B8Y4E3/103-277 DE Uncharacterized protein #=GS A0A1B8Y4E3/103-277 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana; Xenopus tropicalis; #=GF SQ 22 Q54C18/310-497 ----DCAFHLNDV--GVGFPEELAKQYTAETVLCLDFIHEKSIIHCDIKPNNMVIDSDGHIKLLDFGNAKKFN--------QKKPTSNDGILGSPRYISPEVLLFEPQSPAVDYWSLGIVMFELITGTTPFIGETPEEIFESILSRNT-----ECIEIQKDAKDLIIKLLDPNPSTRIGS-----KDIKNHPYFN-GINWDTI---KTSQPIWKP-N--------- Q582V7/145-346 ----DLDKYMNSVPNK-QLDLPTSKLYGAEILMAILTLHEQSVIYRDLKPENILLTGDGHCVLADFGLSKDFYDAKMGENASVTDMRANSFVGSPFYVAPDVLKQREYTNAVDFWSFGILLYRMLCGRTPFSGKNMKEVFDNILYSDLRFP--STVSIPSEAKDLISRLLVKDAAHRIKG-----PEVKAHPFWT-GINFDEVMQKKVKPPRWVP----------- Q4Q9K2/129-324 ----DLDKYMNSVPKK-QLDPATAQLYGAEILLAIMCLHEHSVIYRDLKPENILLDGEGHCALADFGLSKDFH--KDGQDVSDKELRANSFVGSPFYVAPDVLRQREYTNAVDFWSFGILLYRMLCGRTPFNGRSMTEVFDNILYSDLSFP--SGVAVSPEAKDLISRLLMKDPNRRIKG-----PEVKQHPYWT-GISFEEVAQRKIAPS--------------- E9HCS8/94-284 MIGGDLKSLLSEM--G-YFDEKMATFYTTEVALALEYLHKHGIIHRDVKPDNMLLSDKGHVKLTDFGLSRVHI-------------GRGCVLGTPDYLAPELLRKKPHGPAVDWWSLGICLYEFLLGGPPFNDETPDKIFNNILERNIEWPPEDDDCLSSAAREAIEALLTLDPAERADG-----SQLRTLPLFD-HLSWTQEIL-NADAPFMP------------ A2EHM3/380-442_463-589 ----DLYALLESV--G-SLDEEVAAFYVAELVLAIEYIHSLNVVHCDLKPDNILINDSGHLQLTDFGLSKATK--------SDTNDHKRRVIGTPHYISPESLLRSDYSPKVDWWALGVIAYELVVGEPPFGGNSEAEIFSHIVAGKYEWP--DDVEVSDEYKKFVHDLLNLNPEKRPDA-----EELKKYKIFE-DIDWENLY--NTNAPFVTT----------- F6YG11/99-301 ---GDLEKWTKN---P-QFDYEASIFYSASVVLGLEFLHEHNIVHRDLKLENVLLDESGYIKISDFGLCKMGM---------GVGDLTKSFVGTPYYVAPEIFKREPYGKEVDWWALGVMLFYMVVHKFPFNGKTVHELSRIVQYERPTIP----CTLPSDFYITIKRLLAKYPVNRLGSN-GA-EEVKKSRLFC-NINWDGLLNKTVMPPIMPPVKSSSNNSSSK A0A0N1PC31/130-329 ----DLDKYMNSVPKK-QLDPVTAQLYGAEILLAITCLHDHSVIYRDLKPENILLDREGHCALADFGLSKDFH--KDGQDVSDKDLRANSFVGSPFYVAPDVLRQREYTNAVDFWSFGILLYRMLCGRTPFNGRSMTEVFDNILYSDLSFP--SGVTVSPEAKDLISRLLMKDPNRRIKG-----PEVKAHPFWN-GLNFDDLMQRKVAPPRWTP----------- F0ZMX4/261-452 ---GDCSYHLEDA--G-AFPEDIAKQYIAETVLCLEYIHNNSIVHGDIKPNNMAIDKEGHIKLLDFGSSKKFN--------QKKPTSTNGILGSPRYISPEVLLFEPQSPAVDFWALGVVLFELITGSTPFIGDTPEEIFDSILSRNT-----EEVIIPKDANDLITKLLDPNPATRIGS-----KDIKTHPYFN-DIDWENL---KSTPPSWKP-KSTNN----- A0A1G4IEB5/145-346 ----DLDKYMNSVPNK-QLDLPTSKLYGAEILMAILTLHEQSVIYRDLKPENILLTGDGHCVLADFGLSKDFYDAKMGENASVTDMRANSFVGSPFYVAPDVLKQREYTNAVDFWSFGILLYRMLCGRTPFSGKNMKEVFDNILYSDLRFP--STVSIPSEAKDLISRLLVKDAAHRIKG-----PEVKAHPFWT-GINFDEVMQKKVKPPRWVP----------- A0A088RSK6/130-329 ----DLDKYMNTVPKK-QLDATTAQLYGAEILLAIMCLHEHSVIYRDLKPENILLDAEGHCALADFGLSKDFH--KDGQDVSDKDLRANSFVGSPFYVAPDVLRQREYTSAVDFWSFGILLYRMLCGRTPFNGRSMTEVFDNILYSDLSFP--SGVTVPPEAKDLISRLLMKDPNRRIKG-----PEVKLHPYWN-GINFEEVMQRKIPPPRWTP----------- A0A0N0VF50/130-327 ----DLDKYMNSVPKK-QLDAVTAQLYGAEILLAITCLHEHSVIYRDLKPENILLDGEGHCALADFGLSKDFH--KDGQDVSDKDLRANSFVGSPFYVAPDVLRQREYTNAVDFWSFGILLYRMLCGRTPFNGRSMTEVFDNILYSDLSFP--SGVTLSPEAKDLISRLLMKDPTRRIKG-----PEVKAHPYWN-GISFDDVMQRKIAPPRW------------- A0A3L6LB87/145-346 ----DLDKYMNSVPNK-QLDLPTSKLYGAEILMAILTLHEQSVIYRDLKPENILLTGDGHCVLADFGLSKDFYDAKMGENASVTDMRANSFVGSPFYVAPDVLKQREYTNAVDFWSFGILLYRMLCGRTPFSGKNMKEVFDNILYSDLRFP--STVSIPSEAKDLISRLLVKDAAHRIKG-----PEVKAHPFWT-GINFDEVMQKKVKPPRWVP----------- C9ZKE1/145-346 ----DLDKYMNSVPNK-QLDLPTSKLYGAEILMAILTLHEQSVIYRDLKPENILLTGDGHCVLADFGLSKDFYDAKMGENASVTDMRANSFVGSPFYVAPDVLKQREYTNAVDFWSFGILLYRMLCGRTPFSGKNMKEVFDNILYSDLRFP--STVSIPSEAKDLISRLLVKDAAHRIKG-----PEVKAHPFWT-GINFDEVMQKKVKPPRWVP----------- A0A3Q8INQ4/130-327 ----DLDKYMNSVPKK-QLDPATAQLYGAEILLAIMCLHEHSVIYRDLKPENILLDGEGHCALADFGLSKDFH--KDGQDVSDKDLRANSFVGSPFYVAPDVLRQREYTNAVDFWSFGILLYRMLCGRTPFNGRSMTEVFDNILYSDLSFP--SGVTVSPEAKDLISRLLMKDPNRRIKG-----PEVKQHPYWT-GISFEEVAQRKVAPPRW------------- E9AXW8/130-327 ----DLDKYMNSVPKK-QLDPATAQLYGAEILLAIMCLHEHSVIYRDLKPENILLDGEGHCALADFGLSKDFH--KDGQDVSDKDLRANSFVGSPFYVAPDVLRQREYTNSVDFWSFGILLYRMLCGRTPFNGRSMTEVFDNILYSDLSFP--SGVTVSPEAKDLISRLLMKDPNRRIRG-----PEVKQHPYWT-GINFEEVAQRKIAPPRW------------- A0A3P3Z8S3/130-329 ----DLDKYMNTVPKK-QLDATTAQLYGAEILLAIMCLHEHSVIYRDLKPENILLDAEGHCALADFGLSKDFH--KDGQDVSDKDLRANSFVGSPFYVAPDVLRQREYTSAVDFWSFGILLYRMLCGRTPFNGRSMTEVFDNILYSDLSFP--SGVTIPPEAKDLISRLLMKDPNRRIKG-----PEVKLHPYWN-GINFEEVMQRKIPPPRWTP----------- A4I1T4/130-327 ----DLDKYMNSVPKK-QLDPATAQLYGAEILLAIMCLHEHSVIYRDLKPENILLDGEGHCALADFGLSKDFH--KDGQDVSDKDLRANSFVGSPFYVAPDVLRQREYTNAVDFWSFGILLYRMLCGRTPFNGRSMTEVFDNILYSDLSFP--SGVTVSPEAKDLISRLLMKDPNRRIKG-----PEVKQHPYWT-GISFEEVAQRKVAPPRW------------- E9BHZ9/130-327 ----DLDKYMNSVPKK-QLDPATAQLYGAEILLAIMCLHEHSVIYRDLKPENILLDGEGHCALADFGLSKDFH--KDGQDVSDKDLRANSFVGSPFYVAPDVLRQREYTNAVDFWSFGILLYRMLCGRTPFNGRSMTEVFDNILYSDLSFP--SGVTVSPEAKDLISRLLMKDPNRRIKG-----PEVKQHPYWT-GISFEEVAQRKVAPPRW------------- A4HED7/130-329 ----DLDKYMNTVPKK-QLDATTAQLYGAEILLAIMCLHEHSVIYRDLKPENILLDAEGHCALADFGLSKDFH--KDGQDVSDKDLRANSFVGSPFYVAPDVLRQREYTSAVDFWSFGILLYRMLCGRTPFNGRSMTEVFDNILYSDLSFP--SGVTIPPEAKDLISRLLMKDPNRRIKG-----PEVKLHPYWN-GINFEEVMQRKIPPPRWTP----------- F7D4V7/156-346 ---GDLAKWTRN---R-QFDYRASIFYSASVVLGLEFLHKHNIVHRDLKLENVLLDESGYIKISDFGLCKKGM---------GVGDLTKSFVGTPYYVAPEIFKREPYGKGVDWWALGVMLFYMVFHKFPFDGKAVHELSRIIQYERPTIP----CTVPSDFSLTIKRLLAKYPENRLGSN-GA-EEVKKSRLFC-NINWDGLLNKTVMPPIMP------------ F6TET1/99-282 ---GDLADRLLK---G-SIKQETTVFYAGCVVLGLQFLHKYNIIHRDIKTSNIVIGRDGYAKITDFGLAKRPV---------YGYGMTYTICGTLPYMAPEMLTNKCYTNSVDWWAFGVVLYEMFVRDMPFVAATKDSLSETIKNKEPCYP----KKLTEDSRDILKKLFIKDPKSRLGSQRGA-EEVMECPFFKFYIPWVTVLK--------------------- A0A1B8Y4E3/103-277 ---GDLRQFVRR---C-SMSRKRSAFYAACIISGLEFLHFRGIMHRDIKPENILMDWDGYVKISDYGVAARFT---------SWDPFAANICGTLWYMAPDLFGPKSYTKIVDFWSLGVMIYEMRLGKRPFTGGSIRRTVINIRTTEPKYP----KKLGAPSTEIIKSLLMKDPQKRLGNNENQLNDLKGMAFFK------------------------------- #=GC scorecons 0001974445443114045523453594756565634794557776969669676535974464989667443001111112334235455596739679757445475459959669757746546449947454365545854454236002243544555557459835573495450000047673465530464443422243246231200000000000 #=GC scorecons_70 ____**____________________*_*___*_*__**___********_****___**__*_****_*______________________*_*_*****_*____*___**_*****_**_*__*__**_*____*____*_______*______________*__**___*__*_________***________*____________________________ #=GC scorecons_80 ____*_____________________*_*________**_______*_*__*______**____***__*______________________*_*_*_**__*________**_*__*___*_______**_*_________*______________________*__**___*__*_________*_*_____________________________________ #=GC scorecons_90 ____*_____________________*___________*_______*_*__*______*_____***_________________________*___*__*___________**_*__*___________**___________*_________________________**______*_________________________________________________ //