# STOCKHOLM 1.0 #=GF ID 1.10.510.10/FF/000535 #=GF DE Serine/threonine-protein kinase a #=GF AC 1.10.510.10/FF/000535 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 92.063 #=GS Q08942/18-333 AC Q08942 #=GS Q08942/18-333 OS Trypanosoma brucei brucei #=GS Q08942/18-333 DE Putative serine/threonine-protein kinase A #=GS Q08942/18-333 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; Trypanosoma brucei brucei; #=GS Q08942/18-333 DR EC; 2.7.11.1; #=GS Q580Q4/35-352 AC Q580Q4 #=GS Q580Q4/35-352 OS Trypanosoma brucei brucei TREU927 #=GS Q580Q4/35-352 DE Serine/threonine-protein kinase A, putative #=GS Q580Q4/35-352 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; Trypanosoma brucei brucei; #=GS Q580Q4/35-352 DR GO; GO:0004672; GO:0005524; GO:0006468; GO:0044145; GO:1902412; #=GS Q38B10/23-360 AC Q38B10 #=GS Q38B10/23-360 OS Trypanosoma brucei brucei TREU927 #=GS Q38B10/23-360 DE Protein kinase, putative #=GS Q38B10/23-360 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; Trypanosoma brucei brucei; #=GS Q38B10/23-360 DR GO; GO:0004674; GO:0005524; GO:0006468; GO:0044145; GO:0052106; #=GS Q57YQ0/18-333 AC Q57YQ0 #=GS Q57YQ0/18-333 OS Trypanosoma brucei brucei TREU927 #=GS Q57YQ0/18-333 DE Serine/threonine-protein kinase NrkA #=GS Q57YQ0/18-333 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; Trypanosoma brucei brucei; #=GS Q57YQ0/18-333 DR GO; GO:0004674; GO:0005524; GO:0005634; GO:0006468; #=GS Q57YR8/36-332 AC Q57YR8 #=GS Q57YR8/36-332 OS Trypanosoma brucei brucei TREU927 #=GS Q57YR8/36-332 DE Serine/threonine-protein kinase A, putative #=GS Q57YR8/36-332 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; Trypanosoma brucei brucei; #=GS Q57YR8/36-332 DR GO; GO:0004672; GO:0005524; GO:0006468; #=GS Q580P8/18-335 AC Q580P8 #=GS Q580P8/18-335 OS Trypanosoma brucei brucei TREU927 #=GS Q580P8/18-335 DE Serine/threonine-protein kinase NrkA #=GS Q580P8/18-335 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; Trypanosoma brucei brucei; #=GS Q580P8/18-335 DR GO; GO:0004674; GO:0005524; GO:0006468; #=GS D0MYX0/134-431 AC D0MYX0 #=GS D0MYX0/134-431 OS Phytophthora infestans T30-4 #=GS D0MYX0/134-431 DE Protein kinase, putative #=GS D0MYX0/134-431 DR ORG; Eukaryota; Oomycetes; Peronosporales; Peronosporaceae; Phytophthora; Phytophthora infestans; #=GS A0C5H8/19-354 AC A0C5H8 #=GS A0C5H8/19-354 OS Paramecium tetraurelia #=GS A0C5H8/19-354 DE Uncharacterized protein #=GS A0C5H8/19-354 DR ORG; Eukaryota; Ciliophora; Intramacronucleata; Oligohymenophorea; Peniculida; Parameciidae; Paramecium; Paramecium tetraurelia; #=GS A9V0C3/16-351 AC A9V0C3 #=GS A9V0C3/16-351 OS Monosiga brevicollis #=GS A9V0C3/16-351 DE Predicted protein #=GS A9V0C3/16-351 DR ORG; Eukaryota; Choanoflagellida; Salpingoecidae; Monosiga; Monosiga brevicollis; #=GS A2EE14/3-331 AC A2EE14 #=GS A2EE14/3-331 OS Trichomonas vaginalis #=GS A2EE14/3-331 DE AGC family protein kinase #=GS A2EE14/3-331 DR ORG; Eukaryota; Trichomonadida; Trichomonadidae; Trichomonas; Trichomonas vaginalis; #=GS K3WRS0/134-439 AC K3WRS0 #=GS K3WRS0/134-439 OS Globisporangium ultimum DAOM BR144 #=GS K3WRS0/134-439 DE Uncharacterized protein #=GS K3WRS0/134-439 DR ORG; Eukaryota; Oomycetes; Pythiales; Pythiaceae; Globisporangium; Globisporangium ultimum; #=GS A0A088SGB9/39-344 AC A0A088SGB9 #=GS A0A088SGB9/39-344 OS Leishmania panamensis #=GS A0A088SGB9/39-344 DE Serine/threonine protein kinase, putative #=GS A0A088SGB9/39-344 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania guyanensis species complex; Leishmania panamensis; #=GS M4BHB6/134-432 AC M4BHB6 #=GS M4BHB6/134-432 OS Hyaloperonospora arabidopsidis Emoy2 #=GS M4BHB6/134-432 DE Uncharacterized protein #=GS M4BHB6/134-432 DR ORG; Eukaryota; Oomycetes; Peronosporales; Peronosporaceae; Hyaloperonospora; Hyaloperonospora arabidopsidis; #=GS A0A0M9G0W0/34-367 AC A0A0M9G0W0 #=GS A0A0M9G0W0/34-367 OS Leptomonas pyrrhocoris #=GS A0A0M9G0W0/34-367 DE Uncharacterized protein #=GS A0A0M9G0W0/34-367 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leptomonas; Leptomonas pyrrhocoris; #=GS G0UWG8/24-362 AC G0UWG8 #=GS G0UWG8/24-362 OS Trypanosoma congolense IL3000 #=GS G0UWG8/24-362 DE Uncharacterized protein #=GS G0UWG8/24-362 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Nannomonas; Trypanosoma congolense; #=GS E9BN77/37-346 AC E9BN77 #=GS E9BN77/37-346 OS Leishmania donovani BPK282A1 #=GS E9BN77/37-346 DE Serine/threonine-protein kinase, putative #=GS E9BN77/37-346 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania donovani; #=GS A0A1G4I553/36-332 AC A0A1G4I553 #=GS A0A1G4I553/36-332 OS Trypanosoma equiperdum #=GS A0A1G4I553/36-332 DE Serine/threonine-protein kinase a, putative #=GS A0A1G4I553/36-332 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma equiperdum; #=GS A0A0W8D357/134-433 AC A0A0W8D357 #=GS A0A0W8D357/134-433 OS Phytophthora nicotianae #=GS A0A0W8D357/134-433 DE Serine/threonine-protein kinase nek3 #=GS A0A0W8D357/134-433 DR ORG; Eukaryota; Oomycetes; Peronosporales; Peronosporaceae; Phytophthora; Phytophthora nicotianae; #=GS W2MQ41/134-433 AC W2MQ41 #=GS W2MQ41/134-433 OS Phytophthora parasitica #=GS W2MQ41/134-433 DE NEK protein kinase #=GS W2MQ41/134-433 DR ORG; Eukaryota; Oomycetes; Peronosporales; Peronosporaceae; Phytophthora; Phytophthora parasitica; #=GS H3GXJ5/134-430 AC H3GXJ5 #=GS H3GXJ5/134-430 OS Phytophthora ramorum #=GS H3GXJ5/134-430 DE Uncharacterized protein #=GS H3GXJ5/134-430 DR ORG; Eukaryota; Oomycetes; Peronosporales; Peronosporaceae; Phytophthora; Phytophthora ramorum; #=GS A0A3R7GDE2/134-434 AC A0A3R7GDE2 #=GS A0A3R7GDE2/134-434 OS Phytophthora kernoviae #=GS A0A3R7GDE2/134-434 DE Uncharacterized protein #=GS A0A3R7GDE2/134-434 DR ORG; Eukaryota; Oomycetes; Peronosporales; Peronosporaceae; Phytophthora; Phytophthora kernoviae; #=GS G5AET0/134-434 AC G5AET0 #=GS G5AET0/134-434 OS Phytophthora sojae strain P6497 #=GS G5AET0/134-434 DE Uncharacterized protein #=GS G5AET0/134-434 DR ORG; Eukaryota; Oomycetes; Peronosporales; Peronosporaceae; Phytophthora; Phytophthora sojae; #=GS A0A329SG48/134-433 AC A0A329SG48 #=GS A0A329SG48/134-433 OS Phytophthora cactorum #=GS A0A329SG48/134-433 DE Uncharacterized protein #=GS A0A329SG48/134-433 DR ORG; Eukaryota; Oomycetes; Peronosporales; Peronosporaceae; Phytophthora; Phytophthora cactorum; #=GS A0A3P3ZE17/39-339 AC A0A3P3ZE17 #=GS A0A3P3ZE17/39-339 OS Leishmania braziliensis MHOM/BR/75/M2904 #=GS A0A3P3ZE17/39-339 DE Repressor_of_differentiation_kinase_2 #=GS A0A3P3ZE17/39-339 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania braziliensis species complex; Leishmania braziliensis; #=GS Q4Q5W2/37-346 AC Q4Q5W2 #=GS Q4Q5W2/37-346 OS Leishmania major #=GS Q4Q5W2/37-346 DE Putative serine/threonine-protein kinase #=GS Q4Q5W2/37-346 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania major species complex; Leishmania major; #=GS E9B296/37-344 AC E9B296 #=GS E9B296/37-344 OS Leishmania mexicana MHOM/GT/2001/U1103 #=GS E9B296/37-344 DE Putative serine/threonine-protein kinase #=GS E9B296/37-344 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania mexicana species complex; Leishmania mexicana; #=GS A0A3L6L7V9/35-352 AC A0A3L6L7V9 #=GS A0A3L6L7V9/35-352 OS Trypanosoma brucei equiperdum #=GS A0A3L6L7V9/35-352 DE Serine/threonine-protein kinase a #=GS A0A3L6L7V9/35-352 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; Trypanosoma brucei equiperdum; #=GS A0A1E1J380/39-344 AC A0A1E1J380 #=GS A0A1E1J380/39-344 OS Leishmania guyanensis #=GS A0A1E1J380/39-344 DE Serine/threonine-protein kinase, putative,protein kinase, putative #=GS A0A1E1J380/39-344 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania guyanensis species complex; Leishmania guyanensis; #=GS A4I7A1/37-346 AC A4I7A1 #=GS A4I7A1/37-346 OS Leishmania infantum #=GS A4I7A1/37-346 DE Putative serine/threonine-protein kinase #=GS A4I7A1/37-346 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania infantum; #=GS Q03428/18-335 AC Q03428 #=GS Q03428/18-335 OS Trypanosoma brucei brucei #=GS Q03428/18-335 DE Putative serine/threonine-protein kinase B #=GS Q03428/18-335 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; Trypanosoma brucei brucei; #=GS Q03428/18-335 DR EC; 2.7.11.1; #=GS Q38B11/23-361 AC Q38B11 #=GS Q38B11/23-361 OS Trypanosoma brucei brucei TREU927 #=GS Q38B11/23-361 DE Protein kinase, putative #=GS Q38B11/23-361 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; Trypanosoma brucei brucei; #=GS Q38B11/23-361 DR GO; GO:0004674; GO:0005524; GO:0006468; GO:0044145; GO:0052106; #=GS A0CY06/19-315 AC A0CY06 #=GS A0CY06/19-315 OS Paramecium tetraurelia #=GS A0CY06/19-315 DE Uncharacterized protein #=GS A0CY06/19-315 DR ORG; Eukaryota; Ciliophora; Intramacronucleata; Oligohymenophorea; Peniculida; Parameciidae; Paramecium; Paramecium tetraurelia; #=GS A0A3Q8IFK8/37-346 AC A0A3Q8IFK8 #=GS A0A3Q8IFK8/37-346 OS Leishmania donovani #=GS A0A3Q8IFK8/37-346 DE Repressor of differentiation kinase 2, putative #=GS A0A3Q8IFK8/37-346 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania donovani; #=GS A4HJT5/39-339 AC A4HJT5 #=GS A4HJT5/39-339 OS Leishmania braziliensis #=GS A4HJT5/39-339 DE Putative serine/threonine-protein kinase #=GS A4HJT5/39-339 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania braziliensis species complex; Leishmania braziliensis; #=GS A2EEG6/4-301 AC A2EEG6 #=GS A2EEG6/4-301 OS Trichomonas vaginalis #=GS A2EEG6/4-301 DE AGC family protein kinase #=GS A2EEG6/4-301 DR ORG; Eukaryota; Trichomonadida; Trichomonadidae; Trichomonas; Trichomonas vaginalis; #=GS V9EGR0/134-433 AC V9EGR0 #=GS V9EGR0/134-433 OS Phytophthora parasitica P1569 #=GS V9EGR0/134-433 DE NEK protein kinase #=GS V9EGR0/134-433 DR ORG; Eukaryota; Oomycetes; Peronosporales; Peronosporaceae; Phytophthora; Phytophthora parasitica; #=GS W2R2J6/134-433 AC W2R2J6 #=GS W2R2J6/134-433 OS Phytophthora parasitica INRA-310 #=GS W2R2J6/134-433 DE NEK protein kinase #=GS W2R2J6/134-433 DR ORG; Eukaryota; Oomycetes; Peronosporales; Peronosporaceae; Phytophthora; Phytophthora parasitica; #=GS W2YNW5/134-433 AC W2YNW5 #=GS W2YNW5/134-433 OS Phytophthora parasitica P10297 #=GS W2YNW5/134-433 DE NEK protein kinase #=GS W2YNW5/134-433 DR ORG; Eukaryota; Oomycetes; Peronosporales; Peronosporaceae; Phytophthora; Phytophthora parasitica; #=GS A0A080ZKJ8/134-433 AC A0A080ZKJ8 #=GS A0A080ZKJ8/134-433 OS Phytophthora parasitica P1976 #=GS A0A080ZKJ8/134-433 DE NEK protein kinase #=GS A0A080ZKJ8/134-433 DR ORG; Eukaryota; Oomycetes; Peronosporales; Peronosporaceae; Phytophthora; Phytophthora parasitica; #=GS W2WDW4/134-433 AC W2WDW4 #=GS W2WDW4/134-433 OS Phytophthora parasitica CJ01A1 #=GS W2WDW4/134-433 DE NEK protein kinase #=GS W2WDW4/134-433 DR ORG; Eukaryota; Oomycetes; Peronosporales; Peronosporaceae; Phytophthora; Phytophthora parasitica; #=GS W2G8P3/134-433 AC W2G8P3 #=GS W2G8P3/134-433 OS Phytophthora parasitica #=GS W2G8P3/134-433 DE NEK protein kinase #=GS W2G8P3/134-433 DR ORG; Eukaryota; Oomycetes; Peronosporales; Peronosporaceae; Phytophthora; Phytophthora parasitica; #=GS Q4Q1S3/38-364 AC Q4Q1S3 #=GS Q4Q1S3/38-364 OS Leishmania major #=GS Q4Q1S3/38-364 DE Putative serine/threonine protein kinase #=GS Q4Q1S3/38-364 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania major species complex; Leishmania major; #=GS A4IDC2/38-362 AC A4IDC2 #=GS A4IDC2/38-362 OS Leishmania infantum #=GS A4IDC2/38-362 DE Serine/threonine_protein_kinase_-_putative #=GS A4IDC2/38-362 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania infantum; #=GS E9BTL8/38-362 AC E9BTL8 #=GS E9BTL8/38-362 OS Leishmania donovani BPK282A1 #=GS E9BTL8/38-362 DE Protein kinase, putative #=GS E9BTL8/38-362 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania donovani; #=GS A0A088SKE4/27-369 AC A0A088SKE4 #=GS A0A088SKE4/27-369 OS Leishmania panamensis #=GS A0A088SKE4/27-369 DE Nima-related protein kinase, putative #=GS A0A088SKE4/27-369 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania guyanensis species complex; Leishmania panamensis; #=GS A4HP12/27-369 AC A4HP12 #=GS A4HP12/27-369 OS Leishmania braziliensis #=GS A4HP12/27-369 DE Putative nima-related protein kinase #=GS A4HP12/27-369 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania braziliensis species complex; Leishmania braziliensis; #=GS A0A3P3ZI85/27-369 AC A0A3P3ZI85 #=GS A0A3P3ZI85/27-369 OS Leishmania braziliensis MHOM/BR/75/M2904 #=GS A0A3P3ZI85/27-369 DE Serine/threonine_protein_kinase #=GS A0A3P3ZI85/27-369 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania braziliensis species complex; Leishmania braziliensis; #=GS A0A0N0DVA6/25-373 AC A0A0N0DVA6 #=GS A0A0N0DVA6/25-373 OS Leptomonas pyrrhocoris #=GS A0A0N0DVA6/25-373 DE Uncharacterized protein #=GS A0A0N0DVA6/25-373 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leptomonas; Leptomonas pyrrhocoris; #=GS E9BTL7/27-372 AC E9BTL7 #=GS E9BTL7/27-372 OS Leishmania donovani BPK282A1 #=GS E9BTL7/27-372 DE Uncharacterized protein #=GS E9BTL7/27-372 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania donovani; #=GS A4IDC1/27-372 AC A4IDC1 #=GS A4IDC1/27-372 OS Leishmania infantum #=GS A4IDC1/27-372 DE Serine/threonine_protein_kinase_-_putative #=GS A4IDC1/27-372 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania infantum; #=GS E9ASS2/27-372 AC E9ASS2 #=GS E9ASS2/27-372 OS Leishmania mexicana MHOM/GT/2001/U1103 #=GS E9ASS2/27-372 DE Uncharacterized protein #=GS E9ASS2/27-372 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania mexicana species complex; Leishmania mexicana; #=GS Q4Q1S4/26-372 AC Q4Q1S4 #=GS Q4Q1S4/26-372 OS Leishmania major #=GS Q4Q1S4/26-372 DE Putative nima-related protein kinase #=GS Q4Q1S4/26-372 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania major species complex; Leishmania major; #=GF SQ 52 Q08942/18-333 --------CKYLNKGIVGLGSYGEAYVAESVEDGSLCVAKVMDLSKMSQRDKRYAQSEIKCLANCNHPNIIRYIEDHEEND--------RLLIVMEFADSGNLDEQIKLRGSGDARYFQEHEALFLFLQLCLALDYIHSHKMLHRDIKSANVLLTSTGLVKLGDFGFSHQYEDTVSGVVASTFCGTPYYLAPELWNNKRYNKKADVWSLGVLLYEIMGMKKPFSASNLKGLMSKVLAGTYAPLP-DSFSSEFKRVVDGILVADPNDRPSVREIFQIPY--INKGLKL-FVQALKKNER--IS---------DSVKEVLVTQVSEI---LSSEVSP--------------DAHRFLVSQIN---YDVT------------------ Q580Q4/35-352 ----SRAECKYVKKKLLGQGSFGSAWRVEETATGLIFAAKVMDTNNMSAKDRGFVTNEVKCLSRCNNANIIRHRASYDRGG--------MLLIIMEYADGGDLYRQIKAR-QHAVRHFKEHEVLYIFLQLCLALDHIHGNNMMHRDLKTANVLLTTTGLVKLGDFGFSRQYEDSLSNPVGTTFCGTPYYLSPELWRRAPYSKKSEMWALGVVLYEVMVLKRPFGGRNMDELIDNIVHARRAPLP-NMYSDDLRRVCDQLLSLDPAKRPSLRQLFQLPF--IRRGLET-LRRSVEIHKK--IP---------QQVFNEIAQNIDEV---LSSELPEYE--------GSRVTPHRGMLQ---------------------------- Q38B10/23-360 EATAKEQKKKYWIKRVLGSGATGTVLCAKRTSDGETFAVKVVDLEGMNEGDKNRAQAEVHCLMNCDFFSILKCHEDFAKKDPQNEVNVLMIALVLDYANAGDLRQEIKSR-AKASRTFREHEAGLLFIQVLLALHHVHSRHMIHRDIKSANILLCSNGLIKLGDFGFTKMYSATVSDDVGKTFCGTPYYVAPEIWRRKPYSKKADLFSLGVLLYELLTLRRPFDGESMRDVMNRTLSGQYDPLP-PETSPEMAEIVSLLLSSDPKQRPCSGKLLDMPI--CKLFMSG-LLEIVQTQPG--FE---------GPLRDVIPSDIRNIKQLLRAEKRS---------------IVNQMDESYS---AAI--STAVLE----------- Q57YQ0/18-333 --------CKYLNKGIVGLGSYGEAYVAESVEDGSLCVAKVMDLSKMSQRDKRYAQSEIKCLANCNHPNIIRYIEDHEEND--------RLLIVMEFADSGNLDEQIKLRGTGDARYFQEHEALFLFLQLCLALDYIHSHKMLHRDIKSANVLLTSTGLVKLGDFGFSHQYEDTVSGVVASTFCGTPYYLAPELWNNKRYNKKADVWSLGVLLYEIMGMKKPFSASNLKGLMSKVLAGTYAPLP-DSFSSEFKRVVDGVLVADPNDRPSVREIFQIPY--INKGLKL-FVQALKKNER--IS---------DSVKEVLVTQVSEI---LSSEVSP--------------DAHRFLVSQIN---YDVT------------------ Q57YR8/36-332 -----RTGCRYVKKKLLGQGSFGSVWRVEETATGSIFAAKVMDTNNMSAKDRGFVINEVKCLSRCNNANIIRHHASFNRGG--------MLLIIAEYADGGDLCRQIKVR-QHAGRHFKEHEVLYIFLQLCLALDHIHGNNMMHRDLKSANVLLTTMGLVKLGDFGFSRQYEDSLSNPVGTTFCGTPYYLSPELWRRAPYSKKSEMWALGVVLYEVMMLKRPFGGRNMDELINNIVHARRAPLP-NMYSDELRRVCDQLLSLDPAKRPSLRQLFQQPF--IRRGLDS-LRRSVETHKK--IP---------PRTFSEIARNIDEV---L-------------------------------------------------------- Q580P8/18-335 --------CKYLNKGIVGLGSYGEAYVAESVEDGSLCVAKVMGLSKMSQRDKRYAQSEIKCLANCNHPNIIRYIEDHEEND--------RLLIVMEFADSGNLDEQIKLRGTGDARYFQEHEALFLFLQLCLALDYIHSHKMLHRDIKSANVLLTSTGLVKLGDFGFSHQYEDTVSRVVASTFCGTPYYLAPELWNNKRYNKKADVWSLGVLLYEIMGMKKPFSASNLKGLMSKVLAGTYAPLP-DSFLSGFKHVVDGILVADPNDRPSVRENFQIPY--INKGLKL-FVQALKKNER--IL---------DSVKEVLVSQVSEI---LSSEVSP--------------DAHRFLESQIN---YDVTHR---------------- D0MYX0/134-431 -TSNKSMWQDIEVIRTIGKGTHGTVVLARRKVDGAVVAVKRVRISQISENGRKQADNEVILLKSLYHVNIVRFYDHFLADD--------ELNIVMEYSDGGNLRQLVKLRSREKMGPFPEPVIMSWFAQLVLAVAYIHGKNVLHRDLKAQNVFLTHKNVVKLGDFGISKALA---GDDTANTACGTPESMSPEICRGEPYGKKSDIWSLGCILYEMIMLRRPFEASTLPEIFTKICKGEFPPIL-PSFSRELRLLVQLMLQQDASKRPSIEDICRFPF--VQAPIQA-F----------------------------LSEHVSEFQEALELEAKL---------------HQPSLYS---------------------------- A0C5H8/19-354 CQVNETQIKQYKKVKLLGVGAYGKAYLVSSDDQDEIKYVMKVVPQSVS------ANTEASILQNLRHDNIIQYVETFIDNK-------DRLCLIMEYANNGTLGQYLKSR----TQPLPEAQIVDWFTQLCLALQCVHSQKIIHRDIKSENVFLHEDK-IKLGDFGIARSVE----QDLATTFIGTPYYISPEIIQNQPYSYKSDIWSLGVLLYEMCTFKYPFTADSLPALANKIMKAKIQPISAQQYSQNMKNLIQQLLQLDANKRPTIEQILCISF--NHNLENALIQNRI-KQLN-------------IKQQQIVKIPVQPMQKKQQHQVVIKNDEYTQNKKLSREEQQKFMREDIQKKKCQQKPQEVVIE----------- A9V0C3/16-351 ----SGSERRYARTKVLGRGAFGTVFLVEDTETREKAVMKKVILTGLSRKELADTTNEAQIMSRLSHKNIIAFFDSFVEGD--------ALCIIMEYAGGGDLDQVIRNS-KRDGTYLEELRIWHYLIDIAQGLAYLHDQRVLHRDIKPSNVLLDHQGMCKIADLGFSRHLRA--YEQQARSTVGTPLFSAPELCQDLPYGEKADCWALGCLLYELTALTTPFQATNAVALAGKIVKATPDPLP-KQYSVELAFLCDRLLEKSPERRPSAWQVLQYPATSIRAEHRQ-LQQQLAARPS--TPPPPHNQHDDSEALRAIIREQSQLIRDLQQDLAHAD--------LARARLQTELQLAHQ------------------RP----P A2EE14/3-331 -------LPGFVEQKVLGKGTYGCVYKAKRLSDGQSYAVKVINLGNLNHREIEDSVNEIRLMASFSSPFIIRFYEAFCDNR--------RLCIVTEYSRLGDLAHLIERR-KKKRRPFHEDDIWRYLLQMLEGLKVLHNCGVVHRDIKSANILLSAPDLIKIADLGVSTVLH---TTQLARTQIGTPLYLAPEVWKRRPYDSKCDMWSLGVLLYEMMTFTYPFTARTTQELAQRCCLGKF-TIP-HGYSAELVSIVRRLLQVNPLMRPSVDDLLNTQC--IKNRIGM-LAAFVEHSED--LE-------TDDKLLSTIKVPMNVRNLHLPSAAYGKK-----------VSIVKPLEQRLH-MKKGVKLSKDVSV----------- K3WRS0/134-439 -TTTKSMWQDIEVLRTIGKGTHGTVVLARRKVDGAVVAVKRVRTAQITENGRKQADNEVILLKSLYHVNIVRFYDHFLVDD--------ELNIVMEYSDGGNLRQLVKMRSREKMGPFPEGVIMSWFAQLVLAVAYIHGKNVLHRDLKAQNVFLTRKNVVKLGDFGISKALA---GDDTANTACGTPESMSPEICRGEPYGKKSDIWSLGCILYEMIMLKRPFEASTLPEIFTKICKGDYPPIL-PSFSRELRLLVQLMLQQDSSKRPSIEDICRFPF--VQAPIQA-F----------------------------LSQHVSEFQEALELEAKL---------------HQPSLYSMGV-RNTPI------------------- A0A088SGB9/39-344 -------DCQYVKKRLLGQGSFGSAWRVEESATGSVFAAKVMDLNSMSEKDRGFVTNEVKCLSRSRNPHIVRCENAIEREG--------HLLIVMEYADGGDLYKQIKAR-VREMKFFREHEVVFIFLQLCLALDHIHSNKMMHRDLKTANILLTTTGLVKLGDFGFSRQYEDSLSNAVGSTFCGTPYYLSPELWHRQPYSKKSEMWALGVVLYEVMALRRPFTGKNMDELITNICHGRRADLP-PSYTASLRDVCNRLLSVDANMRPTIQELFHEPF--IRSNLET-LKRSVEKHNR--IP---------ADVRDAIARCITQS---LSTEEPPAQ--------LEE------------------------------------- M4BHB6/134-432 -TSNRSMWQDIEILRTIGKGTHGTVVLARRKLDGAVVAVKRVRISQISENGRKQADNEVILLKSLYHVNIVRFYDHFLADD--------ELNIVMEYSDGGNLRQLVKLRAREKMGPFPEPVIMSWFAQLVLAVAYIHGKNVLHRDLKAQNVFLTHKNVVKLGDFGISKALA---GDDTANTACGTPESMSPEICRGEPYGKKSDIWSLGCILYEMIMLRRPFEASTLPEIFSKICKGEFPSIF-PSFSRELRLLVQLMLQQDASKRPSIEDICRFPF--VQAPIQA-F----------------------------LSEHVSEFQEALELEAKL---------------HQPSLYSM--------------------------- A0A0M9G0W0/34-367 ---RHSLPVRYYLDTVLGSGTSGTVLYARRVRDNQPFAIKVMDVEGYTPQEIMRSSGEVCCLLSCDYFSIVKCHEDFVYRDKKNPDNVIMMAMVLDYANAGDLRQEIRNR-SKTNRPFAEHEAGLLFIQVLLAVHHVHSKRMIHRDIKSANILLCSNGLAKLGDFGFSKHYAATVSEDVGRTFCGTPYYVAPEIWRRRPYSKKADMFSLGVLLYELLTLKRPFDGEDIEDVMHKTLAGRFDPLP-DSVSKEMQTIVSALLQSEPRRRPSSKTLLNTPT--CKLYISV-VQEIVQSGEAGGFS---------PDQETIITRQLKQTKEELQVDRCR---------------PQLSAEEVLR---TAVKVS---------------- G0UWG8/24-362 -ATAREQGKKYWIKRILGSGATGTVLCAKRTSDGETFAVKAVDLEGMSEGDRNRAQAEVHCLMNCDFFSILKCHEDFAKSDPQNEENVLMIALVLDYANAGDLRQEIKSR-AKTSRSFREHEAGLLFIQVLLALHHVHSRHMIHRDIKSANILLCSNGLVKLGDFGFTKMYSATVSDDVGKTFCGTPYYVAPEIWRRKPYSKKADLFSLGVLLYELLTLRRPFDGDSMRDVMHKTLSGQYDPLP-PETSAEMVELVSLLLSSDPKARPCSGKLLDMPI--CKLFMSG-LLEIVQTQPA--FQ---------GTLREVIPGDIRNIKEMLKAEKKL---------------AVKQMDESYS---TAV--STVVLEGA--------- E9BN77/37-346 -----TPNCQYVKKRLLGQGSFGSAWRVEESATGNVFAAKVMDLNSMSEKDRGFVTNEVKCLSRCCNPHVVRCENAIEREG--------QLLIVMEYADGGDLYKQIKAR-VREMKFFREHEVVFIFLQLCLALDHIHSNKMMHRDLKTANILLTTTGLVKLGDFGFSRQYEDSLSNAVGSTFCGTPYYLSPELWHRQPYSKKSEMWALGVVLYEVMALRRPFTGKNMDELITNICHGRRSDLP-SSYSASLRDVCNRLLSVDSNTRPTIHELFHEPF--IRSNLET-LKRSVEKHNR--IP---------ADVREAIARCITQS---LNTEEPPAH--------LEEPE----------------------------------- A0A1G4I553/36-332 -----RTGCRYVKKKLLGQGSFGSVWRVEETATGSIFAAKVMDTNNMSAKDRGFVINEVKCLSRCNNANIIRHHASFNRGG--------MLLIIAEYADGGDLCRQIKVR-QHAGRHFKEHEVLYIFLQLCLALDHIHGNNMMHRDLKSANVLLTTMGLVKLGDFGFSRQYEDSLSNPVGTTFCGTPYYLSPELWRRAPYSKKSEMWALGVVLYEVMMLKRPFGGRNMDELINNIVHARRAPLP-NMYSDELRRVCDQLLSLDPAKRPSLRQLFQQPF--IRRGLDS-LRRSVETHKK--IP---------PRTFSEIARNIDEV---L-------------------------------------------------------- A0A0W8D357/134-433 -TSNKSMWQDIEVIRTIGKGTHGTVVLARRKVDGAVVAVKRVRISQISENGRKQADNEVILLKSLYHVNIVRFYDHFLADD--------ELNIVMEYSDGGNLRQLVKLRSREKMGPFPEPVIMSWFAQLVLAVAYIHGKNVLHRDLKAQNVFLTHKNVVKLGDFGISKALA---GDDTANTACGTPESMSPEICRGEPYGKKSDIWSLGCILYEMIMLRRPFEASTLPEIFTKICKGEYPPIL-PSFSRELRLLVQLMLQQDASKRPSIEDICRFPF--VQAPIQA-F----------------------------LSEHVSEFQEALELEAKL---------------HQPSLYSTG-------------------------- W2MQ41/134-433 -TSNKSMWQDIEVIRTIGKGTHGTVVLARRKVDGAVVAVKRVRISQISENGRKQADNEVILLKSLYHVNIVRFYDHFLADD--------ELNIVMEYSDGGNLRQLVKLRSREKMGPFPEPVIMSWFAQLVLAVAYIHGKNVLHRDLKAQNVFLTHKNVVKLGDFGISKALA---GDDTANTACGTPESMSPEICRGEPYGKKSDIWSLGCILYEMIMLRRPFEASTLPEIFTKICKGEYPPIL-PSFSRELRLLVQLMLQQDASKRPSIEDICRFPF--VQAPIQA-F----------------------------LSEHVSEFQEALELEAKL---------------HQPSLYSTG-------------------------- H3GXJ5/134-430 -TSNKSMWQDIEVIRTIGKGTHGTVVLARRKVDGAVVAVKRVRISQISENGRKQADNEVILLKSLYHVNIVRFYDHFLADD--------ELNIVMEYSDGGNLRQLVKLRSREKMGPFPEPVIMSWFAQLVLAVAYIHGKNVLHRDLKAQNVFLTHKNVVKLGDFGISKALA---GDDTANTACGTPESMSPEICRGEPYGKKSDIWSLGCILYEMIMLRRPFEASTLPEIFTKICKGEFPPIL-PSFSRELRLLVQLMLQQDASKRPSIEDICRFPF--VQAPIQA-F----------------------------LSEHVAEFQEALELEAKL---------------HQPSLY----------------------------- A0A3R7GDE2/134-434 -TSNKSMWQDIEVIRTIGKGTHGTVVLARRKLDGAVVAVKRVRISQISENGRKQADNEVILLKSLYHVNIVRFYDHFLADD--------ELNIVMEYSDGGNLRQLVKLRSREKMGPFPEPVIMSWFAQLVLAVAYIHGKNVLHRDLKAQNIFLTHKNVVKLGDFGISKALA---GDDTANTACGTPESMSPEICRGEPYGKKSDIWSLGCILYEMIMLRRPFEASTLPEIFTKICKGEFPPIL-PTFSRELRLLVQLMLQQDASKRPSIEDICRFPF--VQAPIQA-F----------------------------LSEHVTEFQEALELEAKL---------------HQPSLYSTGA------------------------- G5AET0/134-434 -TSNKSMWQDIEVIRTIGKGTHGTVVLARRKLDGAVVAVKRVRISQISENGRKQADNEVILLKSLYHVNIVRFYDHFLADD--------ELNIVMEYSDGGNLRQLVKLRAREKMGPFPEPVIMSWFAQLVLAVAYIHGKNVLHRDLKAQNVFLTHKNVVKLGDFGISKALA---GDATANTACGTPESMSPEICRGEPYGKKSDIWSLGCILYEMIMLRRPFEASTLPEIFTKICKGEFPPIL-PSFSRDLRLLVQLMLQQDASKRPSIEDICRFPF--VQNPIQA-F----------------------------LSEHVSEFQEALELEAKL---------------HQPSLYSAGN------------------------- A0A329SG48/134-433 -TSNKSMWQDIEVIRTIGKGTHGTVVLARRKVDGAVVAVKRVRISQISENGRKQADNEVILLKSLYHVNIVRFYDHFLADD--------ELNIVMEYSDGGNLRQLVKLRSREKMGPFPEPVIMSWFAQLVLAVAYIHGKNVLHRDLKAQNVFLTHKNVVKLGDFGISKALA---GDDTANTACGTPESMSPEICRGEPYGKKSDIWSLGCILYEMIMLRRPFEASTLPEIFTKICKGEFPPIL-PSFSRELRLLVQLMLQQDASKRPSIEDICRFPF--VQAPIQS-F----------------------------LSEHVSEFQEALELEAKL---------------HQPSLYSTG-------------------------- A0A3P3ZE17/39-339 -------DCQYVKKRLLGQGSFGSAWRVEESATGSVFAAKVMDLNSMSEKDRGFVTNEVKCLSRSRNPHIVRCENAIEREG--------HLLIVMEYADGGDLYKQIKAR-VREMKFFREHEVVFIFLQLCLALDHIHSNKMMHRDLKTANILLTTTGLVKLGDFGFSRQYEDSLSNAVGSTFCGTPYYLSPELWHRQPYSKKSEMWALGVVLYEVMALRRPFTGKNMDELITNICHGRRADLP-PSYTASLRDVCNRLLSVDANMRPTIQELFHEPF--IRSNLET-LKRSVEKHNR--IP---------ADVRDAIARCITQS---LSTEEPP-------------------------------------------------- Q4Q5W2/37-346 -----TPNCQYVKKRLLGQGSFGSAWRVEESATGNVFAAKVMDLNNMSEKDRGFVTNEVKCLSRCCNPHVVRCENAIEREG--------QLLIVMEYADGGDLYKQIKAR-VREMKFFREHEVVFIFLQLCLALDHIHSNKMMHRDLKTANILLTTTGLVKLGDFGFSRQYEDSLSNAVGSTFCGTPYYLSPELWHRQPYSKKSEMWALGVVLYEVMALRRPFTGKNMDELITNICHGRCSDLP-SSYSASLRDVCNRLLSVDPNTRPTIHELFHEPF--IRSNLET-LKRSVEKHNR--IP---------ADVREAIARCITQS---LNTEEPPAH--------LEEPE----------------------------------- E9B296/37-344 -----TPNCQYVKKRLLGQGSFGSAWRVEESATGSVFAAKVMDLNSMSEKDRGFVTNEVKCLSRCCNPHVVRCENAIEREG--------QLLIVMEYADGGDLYKQIKAR-VREMKFFREHEVVFIFLQLCLALDHIHSNKMMHRDLKTANILLTTTGLVKLGDFGFSRQYEDSLSNAVGSTFCGTPYYLSPELWHRQPYSKKSEMWALGVVLYEVMALRRPFTGKNMDELITNICHGRRSDLP-SSYSASLRDVCNRLLSVDPNTRPTIHELFHEPF--IQSNLET-LKRSVEKHSR--IP---------ADVREAIARCITQS---LNTEEPPAH--------LDE------------------------------------- A0A3L6L7V9/35-352 ----SRAECKYVKKKLLGQGSFGSAWRVEETATGLIFAAKVMDTNNMSAKDRGFVTNEVKCLSRCNNANIIRHRASYDRGG--------MLLIIMEYADGGDLYRQIKAR-QHAVRHFKEHEVLYIFLQLCLALDHIHGNNMMHRDLKTANVLLTTTGLVKLGDFGFSRQYEDSLSNPVGTTFCGTPYYLSPELWRRAPYSKKSEMWALGVVLYEVMVLKRPFGGRNMDELIDNIVHARRAPLP-NMYSDDLRRVCDQLLSLDPAKRPSLRQLFQLPF--IRRGLET-LRRSVEIHKK--IP---------QQVFNEIAQNIDEV---LSSELPEYE--------GSRVTPHRGMLQ---------------------------- A0A1E1J380/39-344 -------DCQYVKKRLLGQGSFGSAWRVEESATGSVFAAKVMDLNSMSEKDRGFVTNEVKCLSRSRNPHIVRCENAIEREG--------HLLIVMEYADGGDLYKQIKAR-VREMKFFREHEVVFIFLQLCLALDHIHSNKMMHRDLKTANILLTTTGLVKLGDFGFSRQYEDSLSNAVGSTFCGTPYYLSPELWHRQPYSKKSEMWALGVVLYEVMALRRPFTGKNMDELITNICHGRRADLP-PSYTASLRDVCNRLLSVDANMRPTIQELFHEPF--IRSNLET-LKRSVEKHNR--IP---------ADVRDAIARCITQS---LSTEEPPAQ--------LEE------------------------------------- A4I7A1/37-346 -----TPNCQYVKKRLLGQGSFGSAWRVEESATGNVFAAKVMDLNSMSEKDRGFVTNEVKCLSRCCNPHVVRCENAIEREG--------QLLIVMEYADGGDLYKQIKAR-VREMKFFREHEVVFIFLQLCLALDHIHSNKMMHRDLKTANILLTTTGLVKLGDFGFSRQYEDSLSNAVGSTFCGTPYYLSPELWHRQPYSKKSEMWALGVVLYEVMALRRPFTGKNMDELITNICHGRRSDLP-SSYSASLRDVCNRLLSVDSNTRPTIHELFHEPF--IRSNLET-LKRSVEKHNR--IP---------ADVREAIARCITQS---LNTEEPPAH--------LEEPE----------------------------------- Q03428/18-335 --------CKYLNKGIVGLGSYGEGYVAERVEDGSLCVAKVMDLSKMSRRDKRYAQSEIKYPTNCNHPNIIRYIEDHEEND--------RLLIVMEFADSGNLDEQIKPWGTGDARYFQEHEALFLFLQLCLALDYIHSHKMLHRDIKSANVLLTSTGLVKLGDFGFSHQYEDTVSGVVASTFCGTPYYLAPELWNNLRYNKKADVWSLGVLLYEIMGMKKPFSASNLKGLMSKVLAGTYAPLP-DSFSSEFKRVVDGILVADPNDRPSVRENFQIPY--INKGLKL-FVQALKKNER--IL---------DSVKEVLVSQVSEI---LSSEVSP--------------DAHRFLESQIN---YDVTHR---------------- Q38B11/23-361 EATAKEQKKKYWIKRVLGSGATGTVLCAKRTSDGETFAVKVVDLEGMNEGDKNRAQAEVHCLMNCDFFSILKCHEDFAKKDPQNEVNVLMIALVLDYANAGDLRQEIKSR-AKTSRAFREHEAGLLFIQVLLALHHVHSRHMIHRDIKSANILLCSNGLIKLGDFGFTKMYSATVSDDVGKTFCGTPYYVAPEIWRRKPYSKKADLFSLGVLLYELLTLRRPFDGESMRDVMNRTLSGQYDPLP-PETSPEMAEIVSLLLSSDPKQRPCSGKLLDMPI--CKLFMSG-LLEIVQTQPA--FE---------GPLRDVIPSDIRNIKQLLRADKRS---------------VVKQMDESYS---TAI--STAVLEG---------- A0CY06/19-315 MQIDETIIKQYKKQRLLGVGAYGKAYLVTSDDENQIKYVMKVLPQSPS------AKQEALILQNLRHENIIQYVETFVDSK-------NRLCIIMEYANNGTLGQYIKSR----QQPLPETQIVDWFTQLCLAIQCVHSQRIIHRDIKAENVFLQDDK-LKLGDFGIARSVE----QTLATTFIGTPYYLSPEIIQNQPYSYKSDIWALGVLLYEMCTFKYPFQAESLPGLATKIIKGKIQPISAQVYSQNMKNLIQSLLQIDQNKRPSIEQILCI------------IQSLLRKSNN-------------LKQDQIIKYQIVTNNKASSITDV----------------------------------KEIVTLGYYK------- A0A3Q8IFK8/37-346 -----TPNCQYVKKRLLGQGSFGSAWRVEESATGNVFAAKVMDLNSMSEKDRGFVTNEVKCLSRCCNPHVVRCENAIEREG--------QLLIVMEYADGGDLYKQIKAR-VREMKFFREHEVVFIFLQLCLALDHIHSNKMMHRDLKTANILLTTTGLVKLGDFGFSRQYEDSLSNAVGSTFCGTPYYLSPELWHRQPYSKKSEMWALGVVLYEVMALRRPFTGKNMDELITNICHGRRSDLP-SSYSASLRDVCNRLLSVDSNTRPTIHELFHEPF--IRSNLET-LKRSVEKHNR--IP---------ADVREAIARCITQS---LNTEEPPAH--------LEEPE----------------------------------- A4HJT5/39-339 -------DCQYVKKRLLGQGSFGSAWRVEESATGSVFAAKVMDLNSMSEKDRGFVTNEVKCLSRSRNPHIVRCENAIEREG--------HLLIVMEYADGGDLYKQIKAR-VREMKFFREHEVVFIFLQLCLALDHIHSNKMMHRDLKTANILLTTTGLVKLGDFGFSRQYEDSLSNAVGSTFCGTPYYLSPELWHRQPYSKKSEMWALGVVLYEVMALRRPFTGKNMDELITNICHGRRADLP-PSYTASLRDVCNRLLSVDANMRPTIQELFHEPF--IRSNLET-LKRSVEKHNR--IP---------ADVRDAIARCITQS---LSTEEPP-------------------------------------------------- A2EEG6/4-301 --------PGFLQEKVLGKGSYGTVYKAKRIANDQSYAVKIVNTAGMCKRELEDSVNEIRLMASFNSPFIISFYEAFALQT--------RLCVITEYARLGDLSKLIDRR-KRTNRPLLEDDIWRFLIQVTEGLRVLHEKGVVHRDIKSANLLLCAPDLVKIGDLGISTILH---SHQFAKTQIGTPLYLAPEIWRRRPYDAKCDMWSLGVVLYEMLNFSFPFIANSTEELGRRILAGRIGPIR-NGYSSEIQNIVNLLLQTNPDNRPSSEELMNMPC--IKNRMHL-IASLLPEEQQ--LLH----SHDDFDILPTIKVPRKINQCA--------------------------------------------------------- V9EGR0/134-433 -TSNKSMWQDIEVIRTIGKGTHGTVVLARRKVDGAVVAVKRVRISQISENGRKQADNEVILLKSLYHVNIVRFYDHFLADD--------ELNIVMEYSDGGNLRQLVKLRSREKMGPFPEPVIMSWFAQLVLAVAYIHGKNVLHRDLKAQNVFLTHKNVVKLGDFGISKALA---GDDTANTACGTPESMSPEICRGEPYGKKSDIWSLGCILYEMIMLRRPFEASTLPEIFTKICKGEYPPIL-PSFSRELRLLVQLMLQQDASKRPSIEDICRFPF--VQAPIQA-F----------------------------LSEHVSEFQEALELEAKL---------------HQPSLYSTG-------------------------- W2R2J6/134-433 -TSNKSMWQDIEVIRTIGKGTHGTVVLARRKVDGAVVAVKRVRISQISENGRKQADNEVILLKSLYHVNIVRFYDHFLADD--------ELNIVMEYSDGGNLRQLVKLRSREKMGPFPEPVIMSWFAQLVLAVAYIHGKNVLHRDLKAQNVFLTHKNVVKLGDFGISKALA---GDDTANTACGTPESMSPEICRGEPYGKKSDIWSLGCILYEMIMLRRPFEASTLPEIFTKICKGEYPPIL-PSFSRELRLLVQLMLQQDASKRPSIEDICRFPF--VQAPIQA-F----------------------------LSEHVSEFQEALELEAKL---------------HQPSLYSTG-------------------------- W2YNW5/134-433 -TSNKSMWQDIEVIRTIGKGTHGTVVLARRKVDGAVVAVKRVRISQISENGRKQADNEVILLKSLYHVNIVRFYDHFLADD--------ELNIVMEYSDGGNLRQLVKLRSREKMGPFPEPVIMSWFAQLVLAVAYIHGKNVLHRDLKAQNVFLTHKNVVKLGDFGISKALA---GDDTANTACGTPESMSPEICRGEPYGKKSDIWSLGCILYEMIMLRRPFEASTLPEIFTKICKGEYPPIL-PSFSRELRLLVQLMLQQDASKRPSIEDICRFPF--VQAPIQA-F----------------------------LSEHVSEFQEALELEAKL---------------HQPSLYSTG-------------------------- A0A080ZKJ8/134-433 -TSNKSMWQDIEVIRTIGKGTHGTVVLARRKVDGAVVAVKRVRISQISENGRKQADNEVILLKSLYHVNIVRFYDHFLADD--------ELNIVMEYSDGGNLRQLVKLRSREKMGPFPEPVIMSWFAQLVLAVAYIHGKNVLHRDLKAQNVFLTHKNVVKLGDFGISKALA---GDDTANTACGTPESMSPEICRGEPYGKKSDIWSLGCILYEMIMLRRPFEASTLPEIFTKICKGEYPPIL-PSFSRELRLLVQLMLQQDASKRPSIEDICRFPF--VQAPIQA-F----------------------------LSEHVSEFQEALELEAKL---------------HQPSLYSTG-------------------------- W2WDW4/134-433 -TSNKSMWQDIEVIRTIGKGTHGTVVLARRKVDGAVVAVKRVRISQISENGRKQADNEVILLKSLYHVNIVRFYDHFLADD--------ELNIVMEYSDGGNLRQLVKLRSREKMGPFPEPVIMSWFAQLVLAVAYIHGKNVLHRDLKAQNVFLTHKNVVKLGDFGISKALA---GDDTANTACGTPESMSPEICRGEPYGKKSDIWSLGCILYEMIMLRRPFEASTLPEIFTKICKGEYPPIL-PSFSRELRLLVQLMLQQDASKRPSIEDICRFPF--VQAPIQA-F----------------------------LSEHVSEFQEALELEAKL---------------HQPSLYSTG-------------------------- W2G8P3/134-433 -TSNKSMWQDIEVIRTIGKGTHGTVVLARRKVDGAVVAVKRVRISQISENGRKQADNEVILLKSLYHVNIVRFYDHFLADD--------ELNIVMEYSDGGNLRQLVKLRSREKMGPFPEPVIMSWFAQLVLAVAYIHGKNVLHRDLKAQNVFLTHKNVVKLGDFGISKALA---GDDTANTACGTPESMSPEICRGEPYGKKSDIWSLGCILYEMIMLRRPFEASTLPEIFTKICKGEYPPIL-PSFSRELRLLVQLMLQQDASKRPSIEDICRFPF--VQAPIQA-F----------------------------LSEHVSEFQEALELEAKL---------------HQPSLYSTG-------------------------- Q4Q1S3/38-364 -------PFRYYLDTVLGSGTSGTVLYARRVRDDHPFAVKVMDVEGYTPQEIMRASGEVCCLLSCDYFSIVKCHEDFVYSDERNPESVSMMAMVLDYANAGDLRQEIKSR-SKTNRPFAEHEAGLIFIQVLLAVHHVHSKRMIHRDIKSANILLCSNGLAKLGDFGFSKHYAATVSEDVGRTFCGTPYYVAPEIWRRRPYSKKADMFSLGVLLYELLTLKRPFDGEDIEEVMHKTLAGLYDPLP-DSISKEMQTIVSALLQSEPKKRPSSKTLLNTPT--CKLYISV-VREIVQSGETGGFS---------AEQETTIARQLKQTKEELQVDRRR---------------PPLSMEDVLR---TTV------------------- A4IDC2/38-362 -------PFRYYLDTVLGSGTSGTVLYARRVRDDYPFAVKVMDVEGYTPQEIMRASGEVCCLLSCDYFSIVKCHEDFVYSDERNPESVSMMAMVLDYANAGDLRQEIKNR-SKTNRPFAEHEAGLIFIQVLLAVHHVHSKRMIHRDIKSANILLCSNGLAKLGDFGFSKHYAATVSDDVGRTFCGTPYYVAPEIWRRRPYSKKADMFSLGVLLYELLTLKRPFDGEDIEEVMHKTLAGRFDPLP-DSISKEMQTIVSALLQSEPKKRPSSKTLLNTPT--CKLYISV-VREIVQSGEASGFS---------VEQETTITRQLKQTKEELQVDRRR---------------PPLSMEDVLR---T--------------------- E9BTL8/38-362 -------PFRYYLDTVLGSGTSGTVLYARRVRDDYPFAVKVMDVEGYTPQEIMRASGEVCCLLSCDYFSIVKCHEDFVYSDERNPESVSMMAMVLDYANAGDLRQEIKNR-SKTNRPFAEHEAGLIFIQVLLAVHHVHSKRMIHRDIKSANILLCSNGLAKLGDFGFSKHYAATVSDDVGRTFCGTPYYVAPEIWRRRPYSKKADMFSLGVLLYELLTLKRPFDGEDIEEVMHKTLAGRFDPLP-DSISKEMQTIVSALLQSEPKKRPSSKTLLNTPT--CKLYISV-VREIVQSGEASGFS---------VEQETTITRQLKQTKEELQVDRRR---------------PPLSMEDVLR---T--------------------- A0A088SKE4/27-369 -ATAREQDKKYWISRVLGSGATGTVLCAKRVSDGEGFAVKCVDMEGMSEADKNRAQAEVDCLLNCNFFSIVKCHEDLAKHDAGNPEMVQMIALVLDYANAGDLRQEIKSR-ARTGRTFREHEAGLLFLQVLLAVHHVHSKHMIHRDIKSANILLCSNGLVKLGDFGFSKMYANTVSDDVGRTFCGTPYYVAPEIWRRCPYSKKADMFSLGVLLYELLTLKRPFDGANMHEVMHKTLAGRFDPLP-SNISPEMRDIVTALLSGDPTRRPSSSRLLNMPI--CKLFLSG-LLEIVQTQPA--FQ---------GGLRDLISNQIQETKRLLVTEKRN---------------IQRMMEESSG---SSVAVSTTILEGA--TP----- A4HP12/27-369 -ATAREQDKKYWISRVLGSGATGTVLCAKRVSDGEGFAVKCVDMEGMSEADKNRAQAEVDCLLNCNFFSIVKCHEDLAKHDAGNPEMVQMIALVLDYANAGDLRQEIKSR-ARTGRTFREHEAGLLFLQVLLAVHHVHSKHMIHRDIKSANILLCSNGLVKLGDFGFSKMYANTVSDDVGRTFCGTPYYVAPEIWRRCPYSKKADMFSLGVLLYELLTLKRPFDGANMHEVMHKTLAGRFDPLP-SNISPEMRDIVTALLSGDPTRRPSSSRLLNMPI--CKLFLSG-LLEIVQTQPA--FQ---------GGLRDLISNQIQETKRLLVTEKRN---------------IQRMMEESSG---SSVAVSTTILEGA--TP----- A0A3P3ZI85/27-369 -ATAREQDKKYWISRVLGSGATGTVLCAKRVSDGEGFAVKCVDMEGMSEADKNRAQAEVDCLLNCNFFSIVKCHEDLAKHDAGNPEMVQMIALVLDYANAGDLRQEIKSR-ARTGRTFREHEAGLLFLQVLLAVHHVHSKHMIHRDIKSANILLCSNGLVKLGDFGFSKMYANTVSDDVGRTFCGTPYYVAPEIWRRCPYSKKADMFSLGVLLYELLTLKRPFDGANMHEVMHKTLAGRFDPLP-SNISPEMRDIVTALLSGDPTRRPSSSRLLNMPI--CKLFLSG-LLEIVQTQPA--FQ---------GGLRDLISNQIQETKRLLVTEKRN---------------IQRMMEESSG---SSVAVSTTILEGA--TP----- A0A0N0DVA6/25-373 EATAREQNKKYWISRVLGSGATGTVLCAKRVSDGEGFAVKCVDMEGMSEADKNRAQAEVDCLLNCDYFSILKCHEDLAKRDPNNPENVQMISLVLDYANAGDLRQEIKSR-ARSGRTFREHEAGLLFLQVLLAVHHVHSKHMIHRDIKSANILLCSNGLVKLGDFGFSKMYANTVSDDVGRTFCGTPYYVAPEIWRRRPYSKKADMFSLGVLLYELLTLKRPFDGANMHEVMHKTLAGRFDPLP-SNISPEMRDIVAALLSGDPVRRPSSSRLLNMPI--CKLFLSG-LLEIVQTQPA--FQ---------GGLRESISNQIQETKRMLATEKRQ---------------IQRALEESAG---TSVAASTTILEGA--TPLSETI E9BTL7/27-372 -ATAREQDKKYWISRVLGSGATGTVLCAKRVSDGEGFAVKCVDMEGMSEADKNRAQAEVDCLLNCDFFSIVKCHEDLAKRDANNPEMVQMIALVLDYANAGDLRQEIKSR-ARTGRTFREHEAGLLFLQVLLAVHHVHSKHMIHRDIKSANILLCSNGLVKLGDFGFSKMYANTVSDDVGRTFCGTPYYVAPEIWRRCPYSKKADMFSLGVLLYELLTLKRPFDGANMHEVMHKTLAGRFDPLP-SNISPEMRDIVTALLSGDPGRRPSSSRLLNMPI--CKLFLSG-LLEIVQTQPA--FQ---------GGLRDSISNQIQETKRLLVTEKRH---------------IQRMMEESSG---SSVAASTTILEGA--TPLTT-- A4IDC1/27-372 -ATAREQDKKYWISRVLGSGATGTVLCAKRVSDGEGFAVKCVDMEGMSEADKNRAQAEVDCLLNCDFFSIVKCHEDLAKRDANNPEMVQMIALVLDYANAGDLRQEIKSR-ARTGRTFREHEAGLLFLQVLLAVHHVHSKHMIHRDIKSANILLCSNGLVKLGDFGFSKMYANTVSDDVGRTFCGTPYYVAPEIWRRCPYSKKADMFSLGVLLYELLTLKRPFDGANMHEVMHKTLAGRFDPLP-SNISPEMRDIVTALLSGDPGRRPSSSRLLNMPI--CKLFLSG-LLEIVQTQPA--FQ---------GGLRDSISNQIQETKRLLVTEKRH---------------IQRMMEESSG---SSVAASTTILEGA--TPLTT-- E9ASS2/27-372 -ATAREQDKKYWISRVLGSGATGTVLCAKRVSDGEGFAVKCVDMEGMSEADKNRAQAEVDCLLNCDFFSIVKCHEDLAKRDANNPEMVQMIALVLDYANAGDLRQEIKSR-ARTGRTFREHEAGLLFLQVLLAVHHVHSKHMIHRDIKSANILLCSNGLVKLGDFGFSKMYANTVSDDVGRTFCGTPYYVAPEIWRRCPYSKKADMFSLGVLLYELLTLKRPFDGANMHEVMHKTLAGRFDPLP-SNISPEMRDIVTALLSGDPGRRPSSSRLLNMPI--CKLFLSG-LLEIVQTQPA--FQ---------GGLRDSISNQIQETKRLLVTEKRH---------------IQRMMEESSG---SSVAASTTILEGA--TPLTT-- Q4Q1S4/26-372 EATAREQEKKYWISRVLGSGATGTVLCAKRVSDGEGFAVKCVDMEGMSEADKNRAQAEVDCLLNCDFFSIVKCHEDLAKRDANNPEMVQMIALVLDYANAGDLRQEIKSR-ARTGRTFREHEAGLLFLQVLLAVHHVHSKHMIHRDIKSANILLCSNGLVKLGDFGFSKMYANTVSDDVGRTFCGTPYYVAPEIWRRCPYSKKADMFSLGVLLYELLTLKRPFDGANMHEVMHKTLAGRFDPLP-SNISPEMRDIVTALLSGDPGRRPSSSRLLNMPI--CKLFLSG-LLEIVQTQPA--FH---------GGLRDSISSQIQETKRLLVTEKRH---------------IQRMMEESSG---SSVAASTTILEGA--TPLTT-- #=GC scorecons 0111222234523365694954956336553357344768465444575355336359734835434358665454533460000000036367678665969464783803433548495553348586478646695546599969559769544567988989676354222554564857999465699666538957967666995699955476699464553664466447443665045573666355436943754499654464438400453354305122322222002100000000012222264346453221733633300000000000000023223221100000010000000000000000000 #=GC scorecons_70 ______________*_**_*__*_*__*_____*___***_*_____*_________**__*_______***__________________*_******__***___**_*_______*_*______*_**_***_***___*_*****__****_____*******_**____________*_****____***____**_**_*__***__***___*****______*___*___*___**_____*__*______**__*___***_______*________________________________________*__________*__*_____________________________________________________ #=GC scorecons_80 _________________*_*__*__________*___*_*_______*_________**__*_______*_______________________*_**___*_*___**_*_______*_*______*_*__**____*_____***_*__*__*______******_*_____________*_****____**_____**_**_*___**__***___*__**______________*__________*__________*__*___**________*___________________________________________________*________________________________________________________ #=GC scorecons_90 _________________*_*__*________________*_________________*___*_______*__________________________*___*_*____*_*_______*_*______*_*___*____*_____***_*__*__*______******_______________*__***____**______*__*_____**__***______**____________________________________*______**_____________________________________________________________________________________________________________________ //