# STOCKHOLM 1.0 #=GF ID 1.10.510.10/FF/001230 #=GF DE Spindle assembly checkpoint kinase #=GF AC 1.10.510.10/FF/001230 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 79.150 #=GS Q54WX4/192-373 AC Q54WX4 #=GS Q54WX4/192-373 OS Dictyostelium discoideum #=GS Q54WX4/192-373 DE Aurora kinase #=GS Q54WX4/192-373 DR ORG; Eukaryota; Dictyosteliales; Dictyosteliaceae; Dictyostelium; Dictyostelium discoideum; #=GS Q54WX4/192-373 DR GO; GO:0000278; GO:0000922; GO:0004672; GO:0005515; GO:0005737; GO:0005813; GO:0032133; GO:0032154; GO:0051233; #=GS Q54WX4/192-373 DR EC; 2.7.11.1; #=GS A8ISU1/111-289 AC A8ISU1 #=GS A8ISU1/111-289 OS Chlamydomonas reinhardtii #=GS A8ISU1/111-289 DE Aurora-like kinase #=GS A8ISU1/111-289 DR ORG; Eukaryota; Viridiplantae; Chlorophyta; Chlorophyceae; Chlamydomonadales; Chlamydomonadaceae; Chlamydomonas; Chlamydomonas reinhardtii; #=GS Q59S66/318-525 AC Q59S66 #=GS Q59S66/318-525 OS Candida albicans SC5314 #=GS Q59S66/318-525 DE Spindle assembly checkpoint kinase #=GS Q59S66/318-525 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Debaryomycetaceae; Candida; Candida albicans; #=GS Q59S66/318-525 DR EC; 2.7.11.1; #=GS A2EYI5/123-294 AC A2EYI5 #=GS A2EYI5/123-294 OS Trichomonas vaginalis #=GS A2EYI5/123-294 DE AGC family protein kinase #=GS A2EYI5/123-294 DR ORG; Eukaryota; Trichomonadida; Trichomonadidae; Trichomonas; Trichomonas vaginalis; #=GS C4LY26/125-283 AC C4LY26 #=GS C4LY26/125-283 OS Entamoeba histolytica #=GS C4LY26/125-283 DE Serine/threonine-protein kinase 6, putative #=GS C4LY26/125-283 DR ORG; Eukaryota; Entamoebidae; Entamoeba; Entamoeba histolytica; #=GS H3DWR7/140-321 AC H3DWR7 #=GS H3DWR7/140-321 OS Pristionchus pacificus #=GS H3DWR7/140-321 DE Uncharacterized protein #=GS H3DWR7/140-321 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Diplogasteromorpha; Diplogasteroidea; Neodiplogasteridae; Pristionchus; Pristionchus pacificus; #=GS A0DMI6/150-316 AC A0DMI6 #=GS A0DMI6/150-316 OS Paramecium tetraurelia #=GS A0DMI6/150-316 DE Uncharacterized protein #=GS A0DMI6/150-316 DR ORG; Eukaryota; Ciliophora; Intramacronucleata; Oligohymenophorea; Peniculida; Parameciidae; Paramecium; Paramecium tetraurelia; #=GS F0ZBQ9/167-348 AC F0ZBQ9 #=GS F0ZBQ9/167-348 OS Dictyostelium purpureum #=GS F0ZBQ9/167-348 DE Uncharacterized protein #=GS F0ZBQ9/167-348 DR ORG; Eukaryota; Dictyosteliales; Dictyosteliaceae; Dictyostelium; Dictyostelium purpureum; #=GS C4YSR6/311-518 AC C4YSR6 #=GS C4YSR6/311-518 OS Candida albicans WO-1 #=GS C4YSR6/311-518 DE Spindle assembly checkpoint kinase #=GS C4YSR6/311-518 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Debaryomycetaceae; Candida; Candida albicans; #=GF SQ 9 Q54WX4/192-373 ------GGECFKEL--QKVGSFNEQTAATYTLQIADALRYCHSKHVIHRDIKPENLLIGVGGEIKIADFGWSVH-APNT-----------------------KRSTFCGTLEYLPPEVIEKKGYDQTADVWSLGILIFEFLVGRSPFTSDEEKNIFHNIQENDVYYPS--SISPEAKDLISRLLVSDPHQRITLKDVINHPWIKKHAHPKSLEPTK A8ISU1/111-289 --------ELYKEL--VRCNHFDERTSATYILSLARALHYCHTKHVIHRDVKPENLLVGLNGELKISDFGWSVH-APSN-----------------------RRKTLCGTLDYLPPEMVEGKEHTTSVDNWSLGVLTYEFLFGGPPFEAPGHQETYRRIVRVDIKFPDKPAVSDSAKAFISKLLVKDAHRRLPLLEVQNDPWIKANADPDMLA--- Q59S66/318-525 LLEYSIEGELYTHL--KKLKRFDNIMASNYIFQITQALIFLHQRGIIHRDLKPENIMVSLDNQLKLSDFGWSVQ-INQNQNQNQIHNQTQTQKTPHQKKQKQKRLTICGTLDYLPPEMIESKSHDFSVDIWALGILCYELLVGKPPFEAINRNITYEKIAKVDIKYPS--NLDVDAIDLISKLVVKDPNKRLSLKEVLNHNWIIKNKPK---WPKN A2EYI5/123-294 --------ELFKIL--RENDRFDEETSAFYIMQIVEAIKYCHSKGVIHRDIKPENILIGSDGNLKISDFGWSASISNTN-----------------------RRSTLCGTLDYLPPEMLNGEKYDFAVDIWGIGVLLYEFLTGNAPFEEPERDKTIERIKSVNIKFPD--DMPELAKDLIQKLLQKDPTKRISLGEVGSHPWILQWI--------- C4LY26/125-283 ---------LYGLL--QQAGRFDERRAARYIKATTEALKYCQEMNCIHRDLKPENIMIDHNDQVKLADFGWSVH-T-NT-----------------------KRNTYCGTLDYLCPEIVLEKYYDGSIDQWCLGVLTFELCTGEPPFQSNSREEVMKKVRNVKYSFPS--YLTNDCKDFINKLIQYDPSKRMIMEKQ------------------- H3DWR7/140-321 ------KGELYKRL--QAKGRFDDRTAGTYIYQMADALHYCHSKNVIHRDIKPENILIGSDGELKISDFGWSVH-APSN-----------------------KRRTMCGTLDYLPPEMINGHSHSKHVDIWALGILCYEFLVGKPPFESEDSTKTYEAVKKLRYVFPH--YVTGGARDLITKLLVLEPTQRLPLDKVMEHFWVKGHVDSKKAEMKR A0DMI6/150-316 --------DLYGLMKKQQNKRFNEKMASNIIKQITMAIGYMHSMNVIHRDLKPENILCFNNDVFKISDFGWSVH-TPSN-----------------------RRKTLCGTLDYLCPEMINYQPHDNRVDVWTIGVLAYELVVGRPPFESHNENDTKRKIQHLQYQFPQ--ILSRASFNMIA---IRD---RRSNRSQITHGLLNELL--------- F0ZBQ9/167-348 ------GGECFKEL--QKVGSFNEMTAATYTLQIADALRYCHSKHVIHRDIKPENLLIGINGEIKIADFGWSVH-APNT-----------------------KRNTFCGTLEYLPPEVVENKGYDQTADVWSLGILIYEFLVGHSPFASDEEQRIFNNIKENEVHYPS--AISTDAKDLISKLLISDPHQRISLKDVINHPWIQKNAHPHSLEPTK C4YSR6/311-518 LLEYSIEGELYTHL--KKLKRFDNIMASNYIFQITQALIFLHQRGIIHRDLKPENIMVSLDNQLKLSDFGWSVQ-INQNQNQNQIHNQTQTQKTPHQKKQKQKRLTICGTLDYLPPEMIESKSHDFSVDIWALGILCYELLVGKPPFEAINRNITYEKIAKVDIKYPS--NLDVDAIDLISKLVVKDPNKRLSLKEVLNHNWIIKNKPK---WPKN #=GC scorecons 000000125674270054245966346547736653973747444699995999966543554596699999760444600000000000000000000000793949999799599664353762469494796937966594699552444363457344443794002542363669466443853494463452452552322110001111 #=GC scorecons_70 __________*__*_______***__*__**_____**_*_*____****_******_______*********_____*_______________________**_*_*******_****____**__**_*_****_***__*__**___________*______**__________*_*__*___*___*_________________________ #=GC scorecons_80 __________*__*_______*_______*______*__*_*____****_****_________*__******______________________________*_*_*******_**___________*_*__*_*_**___*__**___________*______**____________*______*___*_________________________ #=GC scorecons_90 _____________________*______________*_________****_****_________*__*****_______________________________*_*_****_**_**___________*_*__*_*__*___*__**___________________*____________*______*___*_________________________ //