# STOCKHOLM 1.0 #=GF ID 1.10.510.10/FF/001091 #=GF DE STE family protein kinase #=GF AC 1.10.510.10/FF/001091 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 90.542 #=GS Q54B33/646-925 AC Q54B33 #=GS Q54B33/646-925 OS Dictyostelium discoideum #=GS Q54B33/646-925 DE Serine/threonine-protein kinase pakE #=GS Q54B33/646-925 DR ORG; Eukaryota; Dictyosteliales; Dictyosteliaceae; Dictyostelium; Dictyostelium discoideum; #=GS Q54B33/646-925 DR GO; GO:0004674; GO:0005524; GO:0006468; GO:0043327; #=GS Q54B33/646-925 DR EC; 2.7.11.1; #=GS Q7Q8U5/35-308 AC Q7Q8U5 #=GS Q7Q8U5/35-308 OS Anopheles gambiae #=GS Q7Q8U5/35-308 DE AGAP010551-PA #=GS Q7Q8U5/35-308 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Cellia; Anopheles gambiae; #=GS A2DIX8/22-303 AC A2DIX8 #=GS A2DIX8/22-303 OS Trichomonas vaginalis #=GS A2DIX8/22-303 DE STE family protein kinase #=GS A2DIX8/22-303 DR ORG; Eukaryota; Trichomonadida; Trichomonadidae; Trichomonas; Trichomonas vaginalis; #=GS H3G5J1/2-263 AC H3G5J1 #=GS H3G5J1/2-263 OS Phytophthora ramorum #=GS H3G5J1/2-263 DE Uncharacterized protein #=GS H3G5J1/2-263 DR ORG; Eukaryota; Oomycetes; Peronosporales; Peronosporaceae; Phytophthora; Phytophthora ramorum; #=GS Q6C9X8/82-368 AC Q6C9X8 #=GS Q6C9X8/82-368 OS Yarrowia lipolytica CLIB122 #=GS Q6C9X8/82-368 DE YALI0D07502p #=GS Q6C9X8/82-368 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Dipodascaceae; Yarrowia; Yarrowia lipolytica; #=GS B8CB28/1-261 AC B8CB28 #=GS B8CB28/1-261 OS Thalassiosira pseudonana #=GS B8CB28/1-261 DE Uncharacterized protein #=GS B8CB28/1-261 DR ORG; Eukaryota; Bacillariophyta; Coscinodiscophyceae; Thalassiosirophycidae; Thalassiosirales; Thalassiosiraceae; Thalassiosira; Thalassiosira pseudonana; #=GS F1A5J4/562-844 AC F1A5J4 #=GS F1A5J4/562-844 OS Dictyostelium purpureum #=GS F1A5J4/562-844 DE Uncharacterized protein #=GS F1A5J4/562-844 DR ORG; Eukaryota; Dictyosteliales; Dictyosteliaceae; Dictyostelium; Dictyostelium purpureum; #=GS A2EQE4/30-331 AC A2EQE4 #=GS A2EQE4/30-331 OS Trichomonas vaginalis #=GS A2EQE4/30-331 DE Non-specific serine/threonine protein kinase #=GS A2EQE4/30-331 DR ORG; Eukaryota; Trichomonadida; Trichomonadidae; Trichomonas; Trichomonas vaginalis; #=GS A2ER42/8-293 AC A2ER42 #=GS A2ER42/8-293 OS Trichomonas vaginalis #=GS A2ER42/8-293 DE STE family protein kinase #=GS A2ER42/8-293 DR ORG; Eukaryota; Trichomonadida; Trichomonadidae; Trichomonas; Trichomonas vaginalis; #=GS A2G0I5/12-293 AC A2G0I5 #=GS A2G0I5/12-293 OS Trichomonas vaginalis #=GS A2G0I5/12-293 DE STE family protein kinase #=GS A2G0I5/12-293 DR ORG; Eukaryota; Trichomonadida; Trichomonadidae; Trichomonas; Trichomonas vaginalis; #=GS A0A1D8NDM7/82-368 AC A0A1D8NDM7 #=GS A0A1D8NDM7/82-368 OS Yarrowia lipolytica #=GS A0A1D8NDM7/82-368 DE Uncharacterized protein #=GS A0A1D8NDM7/82-368 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Dipodascaceae; Yarrowia; Yarrowia lipolytica; #=GF SQ 11 Q54B33/646-925 ---------------------VEDTFEFKEKLGQGGYGAVFKVLHRETNF-PLAIKVLSIT------PTRIKDIEKEIDLLKKCRCPNVLSYYGSISSKL-TELWILMDHCAVGSINDMMKIC----CDTLDEEQIAVVTLNVLNGLGYLHSK-GIVHLDVKAANILLTEDKQIKIADFGVSQQLQTE-YGQANVYIGSPLYMAPEVILKAPYNSKADIWSLGITLIELAEGRPPNRGLRSMNQLVEIPNMPPPKLSNPKDWSPCFNNFLATCLVKDPVQRPSVIDLLSHDFIKNAK---TTEVLSNLVKQTLSSR---------------QS---- Q7Q8U5/35-308 -----------------------DFWDMIGELGDGAFGKVYKAQNRETKQ-LAAAKMCTLED-----EENLSDHMVEIDILSEIKHPNIVGLYEAYSIDD--KLWMLIEYCDGGALDSIMVEL----EKPLTEAQIAYVCKHMCAGLNHLHKN-KVIHRDLKAGNVLLTMDGGVKLADFGVSAKNKHT-MQKHDTFIGTPYWMAPELV--------------------LCETWPPNSEMSPMRVLLKIQKSEPPKLDQPSKWSKHFNDFLARALVKDPQQRPSTEVLMGLSFISGNL---DSKPIKDLLLEYKADVVEEELVDEEAEEPRNSAL--- A2DIX8/22-303 ---RV-HIDTDMNWTFDSTADPNSLFCTIKCIGKGGFGIVCEVLNKVLQQ-TFAGKIINTSFLD---QQNEKTYQQEMKILRTVRSPYIIKYYGCVHLKT--SRMLLMEFCDKGSLRQILDTR----NQVLNEKQIAIVMHDLLMALDALHNKYNIIHRDIKAANLLFNSKYEIKLCDFGASIRKSDT-QDKSNVIIGTPYWLAPEVISGQPYSYASDVWGTGITAVELAEGAPPYVEFPPTKAMIEISRSGFCGLREPSNHTTIFTSFIITCLKSNPEERPTVSELLNHPFIKQVE---------------------------------------- H3G5J1/2-263 ----------------------EEVFELQRKEGAGAFGRVFRACYKKDRTRLAALKVIPVALEAGERGEDIESVRREIQFLRECDHPNVVAFHGAYYKDG--ALWVAMEHCAGGSVGDVRRVR------SLSEREISVIMRGALRGLAYLHSR-RKIHRDVKGGNILLTDAGQVKIADFGVSAQLRDT-LSRRGSFVGTPYWMSPELIQDSDYDFKADIWSLGITAIELADQKPPLFDEHPMRVLIQIPRNPPPQVAHPEKWSAAFLDFLRFCLRKDPAERPTALECMKHEFIR------------------------------------------- Q6C9X8/82-368 ------------------------VVALDVVLGKGSFGKVYKGRIRKTNQ-VCAVKQVNLDE-----EDDIDEIALEVNFLASLRCPFITEYYGSVVDNRDYTLWILMEYCGGGSCADLIKSQ------PFREDHIAVVMRDTLRGLEYLHKQ-RKVHRDIKAANILLTTEGDVKLADFGVSGEMGLS-IKKMRSFVGTPYWMAPEVISKAGYDYKADIWSLGITALELADGSPPLSGLSPMKALSVIPDRECPSLPHGNQFTELFREFIDACMCKDPDSRSSATQLLTLKFVRTTK---RPSILVPLIQQHHKFV---RKLKPAQKRVLN------ B8CB28/1-261 ------------------------EFEIDKMLGEGSFGQVFSASHKPTGA-IVAVKVVPNQQG----DEESIKIMGEIDILSKCNSPYIVGYFECFVLDP-AELWIVQEYCEGGSVSDLIEAAGGRGSFAMPEECIRAACAGIVLGLEYLHKK-EVCHRDIKCGNVLLTNDGHVKLADFGVSAELTNT-INKLKTVVGSPFWMAPEVIKESHYDGRADVWSLGITTIEMAEGAPPHSNLNPLRAIFLIPSKPAPTLADPDNWSPEMSDFIRCCCKKDPSERSDSALLTSHPFV-------------------------------------------- F1A5J4/562-844 ---------------------VEDTFEFKEKLGQGGYGAVFKVLHKETGF-PMAIKVLSIT------PTRIKDIEKEIDLLKKCRCPNVLSYYGSISSKL-TELWILMDYCAVGSIKDMMKTC----CDTLDEDQIAVVTLSVLNGLGYLHSK-GIVHLDVKGANILLTENGDVKLADFGVSQQLQTP-YGQANILIGSPLYMAPEVIQKAPYNFKADIWSLGITLIELAEGRPPNRGLKSMNQLVDIPNMPPPKLSNPKDWTPCFNDFIAKCLTKDPEQRPSVVELLSHDFIKNSK---TPDVLSNLIKQTLSSRVD------------NQS---- A2EQE4/30-331 ----------------------SNIFKVIRKIGAGGFGDVYEMEHIPSGI-HMAGKSVSVEKMT---RTSKTHLAREIDLLRKVMSPYTVQYYGSIDFEG--SPMILLEFCNRGSLYDIMKAK----KMTFSEDQISVIMKDMITALIILHKNFHVLHRDVKAGNILLNSSCQIKLTDFGISCQFSSTSSQRTQTITGTPYWMAPEIMNDDHYGYPADIWSLGITAVELAEGQPPYSELPYTRALVEISTKGFPGFRKGNKYTQEFVNFIRECTVMDPEKRPGPEQLLKHPFILRANDLNREELFSDIIAEPLDFN---EVLKEEEEEDEYASEDEG A2ER42/8-293 QTSSLQQLCEDMNWELDPLARTEDIFEIVEEIGKGGFGSVYKVRHRQSGL-CLAGKTINPDVLT---GSASESIVREIELIKKITTAYTIQFYGNIIYND--EPMLLMEYCDRGSLRDILDFR----GETLTEQQAAFVIADLLTAVHILHTKYKILHRDIKAGNILLNSSGQIKVTDFGLSTEFSNG-KFNTFTPMGTPYWMAPEVINGKPYSFPADVWSIAATAIELIEGGPPYYELEPTKAMLKIARSGFPGFRNPKAMSKEFKDFISHTMSRDPNNRCTIPQLLEHPWIQQIT---------------------------------------- A2G0I5/12-293 ---NL-HVDRDMKWTFDPSVKPEDNFQIIREIGRGGFGAVYEMLHTQSGY-RLAGKVVNEESMS---SSAKQSLLKEIDLLKKINSPYTVQYFGNIIFNK--QQMILMEYCDRGSFRDMIDYR----NLCLTEKQAAIVIKDVLSGILILHTKHKVLHRDIKAANILLMSDGGIRLTDFGISRDFSGG-TLNTMSSIGTPYWMAPEVINSQPYSYPADIWSIGATTIELVEGAPPYCELEPTKAMMNIAAHGFPGFRAPRAVTKEFKDFIAHTMSKDPKNRCTIPQLLKHPWIQQVD---------------------------------------- A0A1D8NDM7/82-368 ------------------------VVALDVVLGKGSFGKVYKGRIRKTNQ-VCAVKQVNLDE-----EDDIDEIALEVNFLASLRCPFITEYYGSVVDNRDYTLWILMEYCGGGSCADLIKSQ------PFREDHIAVVMRDTLRGLEYLHKQ-RKVHRDIKAANILLTTEGDVKLADFGVSGEMGLS-IKKMRSFVGTPYWMAPEVISKAGYDYKADIWSLGITALELADGSPPLSGLSPMKALSVIPDRECPSLPHGNQFTELFREFIDACMCKDPDSRSSATQLLTLKFVRTTK---RPSILVPLIQQHHKFV---RKLKPAQKRVLN------ #=GC scorecons 0000000000000000000000233544333594958939654245344302393945434100000333333433975584444484553677443242003446667694497436554230000114639457646434453673499450444969696696985345478659996935333402253343596967879967233373436757646574578576399335536555643943343736336433632735963255368934954434763536732220001111111110100000000000000000001000000 #=GC scorecons_70 ________________________________*_*_**_**____________*_*____________________**__*_____*____***____________*_***__**__*____________*_*__*__*______**__**______*****__****_____***_***_*_______________***********____*____*_*____*__**_**_**_________*__*_____*___________*__**______**__*_____**___**____________________________________________ #=GC scorecons_80 ________________________________*_*_**_*_____________*_*____________________*___*_____*_____*_______________*_*__**_________________*_____________*__**______*_*_*__*_**______*__***_*_______________*_*__****_*____________________*_*__**____________*_____*___________*__*_______**__*_____*_____*____________________________________________ #=GC scorecons_90 ________________________________*_*__*_*_____________*_*____________________*___*_____________________________*__*__________________*________________**______*_*_*__*_*_______*__***_*_______________*_*__*_**______________________*____**____________*____________________*________*__*________________________________________________________ //