# STOCKHOLM 1.0
#=GF ID 1.10.3270.10/FF/000003
#=GF DE 3-hydroxy-3-methylglutaryl coenzyme A reductase
#=GF AC 1.10.3270.10/FF/000003
#=GF TP FunFam
#=GF DR CATH: v4.3
#=GF DR DOPS: 93.657
#=GS P34135/131-214     AC P34135
#=GS P34135/131-214     OS Dictyostelium discoideum
#=GS P34135/131-214     DE 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1
#=GS P34135/131-214     DR ORG; Eukaryota; Dictyosteliales; Dictyosteliaceae; Dictyostelium; Dictyostelium discoideum; 
#=GS P34135/131-214     DR EC; 1.1.1.34; 
#=GS Q587C0/11-102      AC Q587C0
#=GS Q587C0/11-102      OS Trypanosoma brucei brucei TREU927
#=GS Q587C0/11-102      DE 3-hydroxy-3-methylglutaryl coenzyme A reductase
#=GS Q587C0/11-102      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; Trypanosoma brucei brucei; 
#=GS Q587C0/11-102      DR GO; GO:0005739; GO:0005743; GO:0005759; GO:0036064; 
#=GS Q9Y0F3/9-99        AC Q9Y0F3
#=GS Q9Y0F3/9-99        OS Leishmania major
#=GS Q9Y0F3/9-99        DE 3-hydroxy-3-methylglutaryl coenzyme A reductase
#=GS Q9Y0F3/9-99        DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania major species complex; Leishmania major; 
#=GS Q9Y0F3/9-99        DR GO; GO:0004420; GO:0005739; GO:0010142; 
#=GS Q19207/87-166      AC Q19207
#=GS Q19207/87-166      OS Caenorhabditis elegans
#=GS Q19207/87-166      DE 3-hydroxy-3-methylglutaryl coenzyme A reductase
#=GS Q19207/87-166      DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis elegans; 
#=GS A9V162/50-147      AC A9V162
#=GS A9V162/50-147      OS Monosiga brevicollis
#=GS A9V162/50-147      DE 3-hydroxy-3-methylglutaryl coenzyme A reductase
#=GS A9V162/50-147      DR ORG; Eukaryota; Choanoflagellida; Salpingoecidae; Monosiga; Monosiga brevicollis; 
#=GS H2Y2K4/371-452     AC H2Y2K4
#=GS H2Y2K4/371-452     OS Ciona intestinalis
#=GS H2Y2K4/371-452     DE 3-hydroxy-3-methylglutaryl coenzyme A reductase
#=GS H2Y2K4/371-452     DR ORG; Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Enterogona; Phlebobranchia; Cionidae; Ciona; Ciona intestinalis; 
#=GS F0ZUD9/128-211     AC F0ZUD9
#=GS F0ZUD9/128-211     OS Dictyostelium purpureum
#=GS F0ZUD9/128-211     DE 3-hydroxy-3-methylglutaryl coenzyme A reductase
#=GS F0ZUD9/128-211     DR ORG; Eukaryota; Dictyosteliales; Dictyosteliaceae; Dictyostelium; Dictyostelium purpureum; 
#=GS A0A1G4HY91/11-102  AC A0A1G4HY91
#=GS A0A1G4HY91/11-102  OS Trypanosoma equiperdum
#=GS A0A1G4HY91/11-102  DE 3-hydroxy-3-methylglutaryl coenzyme A reductase
#=GS A0A1G4HY91/11-102  DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma equiperdum; 
#=GS H3F5U5/110-181     AC H3F5U5
#=GS H3F5U5/110-181     OS Pristionchus pacificus
#=GS H3F5U5/110-181     DE Uncharacterized protein
#=GS H3F5U5/110-181     DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Diplogasteromorpha; Diplogasteroidea; Neodiplogasteridae; Pristionchus; Pristionchus pacificus; 
#=GS A0A3L6L6K2/11-102  AC A0A3L6L6K2
#=GS A0A3L6L6K2/11-102  OS Trypanosoma brucei equiperdum
#=GS A0A3L6L6K2/11-102  DE 3-hydroxy-3-methylglutaryl coenzyme A reductase
#=GS A0A3L6L6K2/11-102  DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; Trypanosoma brucei equiperdum; 
#=GS C9ZRC5/11-102      AC C9ZRC5
#=GS C9ZRC5/11-102      OS Trypanosoma brucei gambiense DAL972
#=GS C9ZRC5/11-102      DE 3-hydroxy-3-methylglutaryl coenzyme A reductase
#=GS C9ZRC5/11-102      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; Trypanosoma brucei gambiense; 
#=GS A8XLV8/90-169      AC A8XLV8
#=GS A8XLV8/90-169      OS Caenorhabditis briggsae
#=GS A8XLV8/90-169      DE 3-hydroxy-3-methylglutaryl coenzyme A reductase
#=GS A8XLV8/90-169      DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis briggsae; 
#=GS A0A2G5ULT3/97-176  AC A0A2G5ULT3
#=GS A0A2G5ULT3/97-176  OS Caenorhabditis nigoni
#=GS A0A2G5ULT3/97-176  DE 3-hydroxy-3-methylglutaryl coenzyme A reductase
#=GS A0A2G5ULT3/97-176  DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis nigoni; 
#=GF SQ 13
P34135/131-214             TKTNKK-IPIKELSNEEILIKLEKGEVLAYRLENELG-DCSRAVEIRRMLLEKQLS----------KKIEPIPHEGFDF----AKVQGQCCENVIGYVPI
Q587C0/11-102              --GTGK-TGWGAMSNAELVKAVSSRQLTFYGLEQALEPDYQRAIAVRREVVSDYVASSQSAE-VKRKSLERIPFENYEW----DRVVGQNCENIVGYVPI
Q9Y0F3/9-99                CSAAKG-ESWASMSDTEIMKQVENKKIAFHGLEQALAPDYDRAIAIRREIVKKKICPSPAAT----HPLERVPYKNYDW----SSVVGQSCENILGYVPV
Q19207/87-166              DEISREWKECKDVTPGEAVRLLRRGQAKSRELESRFP--AEQAIPIRRTFIN--------------KKFENLPYLGYDY----TLATECCCENVIGYTPV
A9V162/50-147              TSMDAS-SDFANMTDEAVLQALHNGDIKLHNLEKELR-DCHRAVNVRRAYLADCLHLEGKGSDDSQMTFKDLPADTFDYQNFYGSIEGANCEAVIGYLPL
H2Y2K4/371-452             --------GSDLVTDAEIIALVEKKKIPLYKLETVLQ-DANRGVAIRRKILKTTVIDKSRI-----EAFNHIPHTGYDF----TTATKACCENTVGYVAV
F0ZUD9/128-211             TLKSTK-VPTKELSNLEILEKVEKGEILAYKLESELG-DCTRAVEIRRLLLEKQLQ----------KKLETLPYQQYDF----GKVQGQCCENVIGYVPI
A0A1G4HY91/11-102          --GTGK-TGWGAMSNAELVKAVSSRQLTFYGLEQALEPDYQRAIAVRREVVSDYVASSQSAE-VKRKSLERIPFENYEW----DRVVGQNCENIVGYVPI
H3F5U5/110-181             -----------QLLPGDVLRLLNRGKAKSRELEARLP-DYETAVAVRRAFVAPL------------DKLAKLPYTDYDY----KFVTNACCENVVGYVPV
A0A3L6L6K2/11-102          --GTGK-TGWGAMSNAELVKAVSSRQLTFYGLEQALEPDYQRAIAVRREVVSDYVASSQSAE-VKRKSLERIPFENYEW----DRVVGQNCENIVGYVPI
C9ZRC5/11-102              --GTGK-TGWGAMSNAELVKAVSSRQLTFYGLEQALEPDYQRAIAVRREVVSDYVASSQSAE-VKRKSLERIPFENYEW----DRVVGQNCENIVGYVPI
A8XLV8/90-169              DEITKDWKECKTVSPGESLRLLKRGTAKSRELESRFP--AEQAIPIRRTFIN--------------KKLDKLPYLNYDY----SLAAESCCENIVGYTPV
A0A2G5ULT3/97-176          DEITKDWKECKTVSPGESLRLLKRGTAKSRELESRFP--AEQAIPIRRTFIN--------------KKLDKLPYLNYDY----SLAAESCCENIVGYTPV
#=GC scorecons             1123230232335544745446345443354994373054468747993453212101111000005465469534875000033535459976699586
#=GC scorecons_70          ________________*____*_________**__*______**_***____________________*___*___**____________*******_**
#=GC scorecons_80          ________________*______________**_________*___**________________________*___**____________***__**_*_
#=GC scorecons_90          _______________________________**_____________**________________________*_________________**___**___
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