# STOCKHOLM 1.0 #=GF ID 1.10.290.10/FF/000003 #=GF DE DNA topoisomerase #=GF AC 1.10.290.10/FF/000003 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 94.816 #=GS Q9LVP1/303-433 AC Q9LVP1 #=GS Q9LVP1/303-433 OS Arabidopsis thaliana #=GS Q9LVP1/303-433 DE DNA topoisomerase 3-alpha #=GS Q9LVP1/303-433 DR ORG; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Brassicales; Brassicaceae; Camelineae; Arabidopsis; Arabidopsis thaliana; #=GS Q9LVP1/303-433 DR GO; GO:0000278; GO:0000712; GO:0006281; GO:0007059; GO:0051321; #=GS Q9LVP1/303-433 DR EC; 5.6.2.2; #=GS Q8IDM7/382-510 AC Q8IDM7 #=GS Q8IDM7/382-510 OS Plasmodium falciparum 3D7 #=GS Q8IDM7/382-510 DE DNA topoisomerase #=GS Q8IDM7/382-510 DR ORG; Eukaryota; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania); Plasmodium falciparum; #=GS Q8IDM7/382-510 DR GO; GO:0006268; #=GS Q383X7/285-413 AC Q383X7 #=GS Q383X7/285-413 OS Trypanosoma brucei brucei TREU927 #=GS Q383X7/285-413 DE DNA topoisomerase #=GS Q383X7/285-413 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; Trypanosoma brucei brucei; #=GS Q383X7/285-413 DR GO; GO:0003677; GO:0003917; GO:0005737; GO:0006265; GO:0006268; GO:0006304; GO:0031981; GO:0097014; #=GS Q4Q199/286-414 AC Q4Q199 #=GS Q4Q199/286-414 OS Leishmania major #=GS Q4Q199/286-414 DE DNA topoisomerase #=GS Q4Q199/286-414 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania major species complex; Leishmania major; #=GS Q4Q199/286-414 DR GO; GO:0005737; GO:0031981; GO:0097014; #=GS H1UBJ6/163-287 AC H1UBJ6 #=GS H1UBJ6/163-287 OS Caenorhabditis elegans #=GS H1UBJ6/163-287 DE DNA topoisomerase #=GS H1UBJ6/163-287 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis elegans; #=GS B0R363/281-406 AC B0R363 #=GS B0R363/281-406 OS Halobacterium salinarum R1 #=GS B0R363/281-406 DE DNA topoisomerase 1 #=GS B0R363/281-406 DR ORG; Archaea; Euryarchaeota; Halobacteria; Halobacteriales; Halobacteriaceae; Halobacterium; Halobacterium salinarum; #=GS Q8TMY4/279-403 AC Q8TMY4 #=GS Q8TMY4/279-403 OS Methanosarcina acetivorans C2A #=GS Q8TMY4/279-403 DE DNA topoisomerase 1 #=GS Q8TMY4/279-403 DR ORG; Archaea; Euryarchaeota; Methanomicrobia; Methanosarcinales; Methanosarcinaceae; Methanosarcina; Methanosarcina acetivorans; #=GS W4YMN5/161-285 AC W4YMN5 #=GS W4YMN5/161-285 OS Strongylocentrotus purpuratus #=GS W4YMN5/161-285 DE DNA topoisomerase #=GS W4YMN5/161-285 DR ORG; Eukaryota; Metazoa; Echinodermata; Echinozoa; Echinoidea; Euechinoidea; Echinacea; Echinoida; Strongylocentrotidae; Strongylocentrotus; Strongylocentrotus purpuratus; #=GS W4YTE9/250-374 AC W4YTE9 #=GS W4YTE9/250-374 OS Strongylocentrotus purpuratus #=GS W4YTE9/250-374 DE DNA topoisomerase #=GS W4YTE9/250-374 DR ORG; Eukaryota; Metazoa; Echinodermata; Echinozoa; Echinoidea; Euechinoidea; Echinacea; Echinoida; Strongylocentrotidae; Strongylocentrotus; Strongylocentrotus purpuratus; #=GS Q97ZJ8/279-405 AC Q97ZJ8 #=GS Q97ZJ8/279-405 OS Saccharolobus solfataricus P2 #=GS Q97ZJ8/279-405 DE DNA topoisomerase I family A (TopA) #=GS Q97ZJ8/279-405 DR ORG; Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Saccharolobus; Saccharolobus solfataricus; #=GS A8B577/289-424 AC A8B577 #=GS A8B577/289-424 OS Giardia lamblia ATCC 50803 #=GS A8B577/289-424 DE DNA topoisomerase #=GS A8B577/289-424 DR ORG; Eukaryota; Diplomonadida; Hexamitidae; Giardiinae; Giardia; Giardia intestinalis; #=GS A7S883/290-407 AC A7S883 #=GS A7S883/290-407 OS Nematostella vectensis #=GS A7S883/290-407 DE DNA topoisomerase #=GS A7S883/290-407 DR ORG; Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria; Edwardsiidae; Nematostella; Nematostella vectensis; #=GS B1L3G6/271-403 AC B1L3G6 #=GS B1L3G6/271-403 OS Candidatus Korarchaeum cryptofilum OPF8 #=GS B1L3G6/271-403 DE DNA topoisomerase 1 #=GS B1L3G6/271-403 DR ORG; Archaea; Candidatus Korarchaeota; Candidatus Korarchaeum; Candidatus Korarchaeum cryptofilum; #=GS Q8TPW5/278-408 AC Q8TPW5 #=GS Q8TPW5/278-408 OS Methanosarcina acetivorans C2A #=GS Q8TPW5/278-408 DE DNA topoisomerase, type I #=GS Q8TPW5/278-408 DR ORG; Archaea; Euryarchaeota; Methanomicrobia; Methanosarcinales; Methanosarcinaceae; Methanosarcina; Methanosarcina acetivorans; #=GS E3KC11/351-477 AC E3KC11 #=GS E3KC11/351-477 OS Puccinia graminis f. sp. tritici CRL 75-36-700-3 #=GS E3KC11/351-477 DE DNA topoisomerase #=GS E3KC11/351-477 DR ORG; Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina; Pucciniomycetes; Pucciniales; Pucciniaceae; Puccinia; Puccinia graminis; #=GS A0A0D1C790/307-431 AC A0A0D1C790 #=GS A0A0D1C790/307-431 OS Ustilago maydis 521 #=GS A0A0D1C790/307-431 DE DNA topoisomerase #=GS A0A0D1C790/307-431 DR ORG; Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina; Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Ustilago; Ustilago maydis; #=GS A9U3P7/298-436 AC A9U3P7 #=GS A9U3P7/298-436 OS Physcomitrella patens #=GS A9U3P7/298-436 DE DNA topoisomerase #=GS A9U3P7/298-436 DR ORG; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Bryopsida; Funariidae; Funariales; Funariaceae; Physcomitrella; Physcomitrella patens; #=GS A0DGW1/315-442 AC A0DGW1 #=GS A0DGW1/315-442 OS Paramecium tetraurelia #=GS A0DGW1/315-442 DE DNA topoisomerase #=GS A0DGW1/315-442 DR ORG; Eukaryota; Ciliophora; Intramacronucleata; Oligohymenophorea; Peniculida; Parameciidae; Paramecium; Paramecium tetraurelia; #=GS C4M656/288-412 AC C4M656 #=GS C4M656/288-412 OS Entamoeba histolytica #=GS C4M656/288-412 DE DNA topoisomerase #=GS C4M656/288-412 DR ORG; Eukaryota; Entamoebidae; Entamoeba; Entamoeba histolytica; #=GS A9V1D2/275-399 AC A9V1D2 #=GS A9V1D2/275-399 OS Monosiga brevicollis #=GS A9V1D2/275-399 DE Predicted protein #=GS A9V1D2/275-399 DR ORG; Eukaryota; Choanoflagellida; Salpingoecidae; Monosiga; Monosiga brevicollis; #=GS A0A1D9Q6J0/294-420 AC A0A1D9Q6J0 #=GS A0A1D9Q6J0/294-420 OS Sclerotinia sclerotiorum 1980 UF-70 #=GS A0A1D9Q6J0/294-420 DE DNA topoisomerase #=GS A0A1D9Q6J0/294-420 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes; Helotiales; Sclerotiniaceae; Sclerotinia; Sclerotinia sclerotiorum; #=GS B0ERJ9/288-412 AC B0ERJ9 #=GS B0ERJ9/288-412 OS Entamoeba dispar SAW760 #=GS B0ERJ9/288-412 DE DNA topoisomerase #=GS B0ERJ9/288-412 DR ORG; Eukaryota; Entamoebidae; Entamoeba; Entamoeba dispar; #=GS K2G4I6/288-412 AC K2G4I6 #=GS K2G4I6/288-412 OS Entamoeba nuttalli P19 #=GS K2G4I6/288-412 DE DNA topoisomerase #=GS K2G4I6/288-412 DR ORG; Eukaryota; Entamoebidae; Entamoeba; Entamoeba nuttalli; #=GS A0A3L6S9E6/303-433 AC A0A3L6S9E6 #=GS A0A3L6S9E6/303-433 OS Panicum miliaceum #=GS A0A3L6S9E6/303-433 DE DNA topoisomerase #=GS A0A3L6S9E6/303-433 DR ORG; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Liliopsida; Petrosaviidae; Poales; Poaceae; Panicoideae; Paniceae; Panicinae; Panicum; Panicum miliaceum; #=GS A0A095C2T0/299-423 AC A0A095C2T0 #=GS A0A095C2T0/299-423 OS Cryptococcus gattii VGII R265 #=GS A0A095C2T0/299-423 DE DNA topoisomerase #=GS A0A095C2T0/299-423 DR ORG; Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes; Tremellales; Cryptococcaceae; Cryptococcus; Cryptococcus gattii species complex; Cryptococcus gattii VGII; #=GS D2PJZ0/279-405 AC D2PJZ0 #=GS D2PJZ0/279-405 OS Sulfolobus islandicus L.D.8.5 #=GS D2PJZ0/279-405 DE DNA topoisomerase I #=GS D2PJZ0/279-405 DR ORG; Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Sulfolobus; Sulfolobus islandicus; #=GS A4HPI6/286-414 AC A4HPI6 #=GS A4HPI6/286-414 OS Leishmania braziliensis #=GS A4HPI6/286-414 DE DNA topoisomerase #=GS A4HPI6/286-414 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania braziliensis species complex; Leishmania braziliensis; #=GS A0A1G4IB13/285-413 AC A0A1G4IB13 #=GS A0A1G4IB13/285-413 OS Trypanosoma equiperdum #=GS A0A1G4IB13/285-413 DE DNA topoisomerase #=GS A0A1G4IB13/285-413 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma equiperdum; #=GS A0A0E3NPK1/279-403 AC A0A0E3NPK1 #=GS A0A0E3NPK1/279-403 OS Methanosarcina sp. WH1 #=GS A0A0E3NPK1/279-403 DE DNA topoisomerase 1 #=GS A0A0E3NPK1/279-403 DR ORG; Archaea; Euryarchaeota; Methanomicrobia; Methanosarcinales; Methanosarcinaceae; Methanosarcina; Methanosarcina sp. WH1; #=GS A0A0E3WW23/279-403 AC A0A0E3WW23 #=GS A0A0E3WW23/279-403 OS Methanosarcina barkeri 3 #=GS A0A0E3WW23/279-403 DE DNA topoisomerase 1 #=GS A0A0E3WW23/279-403 DR ORG; Archaea; Euryarchaeota; Methanomicrobia; Methanosarcinales; Methanosarcinaceae; Methanosarcina; Methanosarcina barkeri; #=GS A0A1E7GDF6/279-403 AC A0A1E7GDF6 #=GS A0A1E7GDF6/279-403 OS Methanosarcina sp. Ant1 #=GS A0A1E7GDF6/279-403 DE DNA topoisomerase 1 #=GS A0A1E7GDF6/279-403 DR ORG; Archaea; Euryarchaeota; Methanomicrobia; Methanosarcinales; Methanosarcinaceae; Methanosarcina; Methanosarcina sp. Ant1; #=GS Q8PSK3/279-403 AC Q8PSK3 #=GS Q8PSK3/279-403 OS Methanosarcina mazei Go1 #=GS Q8PSK3/279-403 DE DNA topoisomerase 1 #=GS Q8PSK3/279-403 DR ORG; Archaea; Euryarchaeota; Methanomicrobia; Methanosarcinales; Methanosarcinaceae; Methanosarcina; Methanosarcina mazei; #=GS A4IDA8/286-414 AC A4IDA8 #=GS A4IDA8/286-414 OS Leishmania infantum #=GS A4IDA8/286-414 DE DNA topoisomerase #=GS A4IDA8/286-414 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania infantum; #=GS A0A088S2H6/286-414 AC A0A088S2H6 #=GS A0A088S2H6/286-414 OS Leishmania panamensis #=GS A0A088S2H6/286-414 DE DNA topoisomerase #=GS A0A088S2H6/286-414 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania guyanensis species complex; Leishmania panamensis; #=GS E9AT98/286-414 AC E9AT98 #=GS E9AT98/286-414 OS Leishmania mexicana MHOM/GT/2001/U1103 #=GS E9AT98/286-414 DE DNA topoisomerase #=GS E9AT98/286-414 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania mexicana species complex; Leishmania mexicana; #=GS D0A8E9/285-413 AC D0A8E9 #=GS D0A8E9/285-413 OS Trypanosoma brucei gambiense DAL972 #=GS D0A8E9/285-413 DE DNA topoisomerase #=GS D0A8E9/285-413 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; Trypanosoma brucei gambiense; #=GS A0A0E3L2I7/316-446 AC A0A0E3L2I7 #=GS A0A0E3L2I7/316-446 OS Methanosarcina sp. WWM596 #=GS A0A0E3L2I7/316-446 DE DNA topoisomerase I #=GS A0A0E3L2I7/316-446 DR ORG; Archaea; Euryarchaeota; Methanomicrobia; Methanosarcinales; Methanosarcinaceae; Methanosarcina; Methanosarcina sp. WWM596; #=GS A0A0E3S7M6/278-408 AC A0A0E3S7M6 #=GS A0A0E3S7M6/278-408 OS Methanosarcina lacustris Z-7289 #=GS A0A0E3S7M6/278-408 DE DNA topoisomerase I #=GS A0A0E3S7M6/278-408 DR ORG; Archaea; Euryarchaeota; Methanomicrobia; Methanosarcinales; Methanosarcinaceae; Methanosarcina; Methanosarcina lacustris; #=GS A0A0E3LHR5/302-432 AC A0A0E3LHR5 #=GS A0A0E3LHR5/302-432 OS Methanosarcina vacuolata Z-761 #=GS A0A0E3LHR5/302-432 DE DNA topoisomerase I #=GS A0A0E3LHR5/302-432 DR ORG; Archaea; Euryarchaeota; Methanomicrobia; Methanosarcinales; Methanosarcinaceae; Methanosarcina; Methanosarcina vacuolata; #=GS A0A151LE52/379-507 AC A0A151LE52 #=GS A0A151LE52/379-507 OS Plasmodium gaboni #=GS A0A151LE52/379-507 DE DNA topoisomerase #=GS A0A151LE52/379-507 DR ORG; Eukaryota; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania); Plasmodium gaboni; #=GS E9BU44/286-414 AC E9BU44 #=GS E9BU44/286-414 OS Leishmania donovani BPK282A1 #=GS E9BU44/286-414 DE DNA topoisomerase #=GS E9BU44/286-414 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania donovani; #=GS A0A1E1J7S4/286-414 AC A0A1E1J7S4 #=GS A0A1E1J7S4/286-414 OS Leishmania guyanensis #=GS A0A1E1J7S4/286-414 DE DNA topoisomerase #=GS A0A1E1J7S4/286-414 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania guyanensis species complex; Leishmania guyanensis; #=GS R0GNU4/303-433 AC R0GNU4 #=GS R0GNU4/303-433 OS Capsella rubella #=GS R0GNU4/303-433 DE DNA topoisomerase #=GS R0GNU4/303-433 DR ORG; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Brassicales; Brassicaceae; Camelineae; Capsella; Capsella rubella; #=GS D7MQJ2/303-433 AC D7MQJ2 #=GS D7MQJ2/303-433 OS Arabidopsis lyrata subsp. lyrata #=GS D7MQJ2/303-433 DE DNA topoisomerase #=GS D7MQJ2/303-433 DR ORG; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Brassicales; Brassicaceae; Camelineae; Arabidopsis; Arabidopsis lyrata; Arabidopsis lyrata subsp. lyrata; #=GS M9MAK8/1112-1236 AC M9MAK8 #=GS M9MAK8/1112-1236 OS Moesziomyces antarcticus T-34 #=GS M9MAK8/1112-1236 DE DNA topoisomerase III alpha #=GS M9MAK8/1112-1236 DR ORG; Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina; Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Moesziomyces; Moesziomyces antarcticus; #=GS A0A1D6JPQ3/302-432 AC A0A1D6JPQ3 #=GS A0A1D6JPQ3/302-432 OS Zea mays #=GS A0A1D6JPQ3/302-432 DE DNA topoisomerase #=GS A0A1D6JPQ3/302-432 DR ORG; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Liliopsida; Petrosaviidae; Poales; Poaceae; Panicoideae; Andropogoneae; Tripsacinae; Zea; Zea mays; #=GS Q5KAU9/299-423 AC Q5KAU9 #=GS Q5KAU9/299-423 OS Cryptococcus neoformans var. neoformans JEC21 #=GS Q5KAU9/299-423 DE DNA topoisomerase #=GS Q5KAU9/299-423 DR ORG; Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes; Tremellales; Cryptococcaceae; Cryptococcus; Cryptococcus neoformans species complex; Cryptococcus neoformans; Cryptococcus neoformans var. neoformans; #=GS A0A368SXG3/303-433 AC A0A368SXG3 #=GS A0A368SXG3/303-433 OS Setaria italica #=GS A0A368SXG3/303-433 DE DNA topoisomerase #=GS A0A368SXG3/303-433 DR ORG; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Liliopsida; Petrosaviidae; Poales; Poaceae; Panicoideae; Paniceae; Cenchrinae; Setaria; Setaria italica; #=GS A0A1B6QQB9/356-486 AC A0A1B6QQB9 #=GS A0A1B6QQB9/356-486 OS Sorghum bicolor #=GS A0A1B6QQB9/356-486 DE DNA topoisomerase #=GS A0A1B6QQB9/356-486 DR ORG; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Liliopsida; Petrosaviidae; Poales; Poaceae; Panicoideae; Andropogoneae; Sorghinae; Sorghum; Sorghum bicolor; #=GS A0A0D0WB63/299-423 AC A0A0D0WB63 #=GS A0A0D0WB63/299-423 OS Cryptococcus gattii EJB2 #=GS A0A0D0WB63/299-423 DE DNA topoisomerase #=GS A0A0D0WB63/299-423 DR ORG; Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes; Tremellales; Cryptococcaceae; Cryptococcus; Cryptococcus gattii species complex; Cryptococcus gattii VGI; #=GS A0A0D0UN27/299-423 AC A0A0D0UN27 #=GS A0A0D0UN27/299-423 OS Cryptococcus gattii CA1280 #=GS A0A0D0UN27/299-423 DE DNA topoisomerase #=GS A0A0D0UN27/299-423 DR ORG; Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes; Tremellales; Cryptococcaceae; Cryptococcus; Cryptococcus gattii species complex; Cryptococcus gattii VGIII; #=GS A0A0D0XTS2/299-423 AC A0A0D0XTS2 #=GS A0A0D0XTS2/299-423 OS Cryptococcus gattii VGIV IND107 #=GS A0A0D0XTS2/299-423 DE DNA topoisomerase #=GS A0A0D0XTS2/299-423 DR ORG; Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes; Tremellales; Cryptococcaceae; Cryptococcus; Cryptococcus gattii species complex; Cryptococcus gattii VGIV; #=GS G0PNJ8/98-222 AC G0PNJ8 #=GS G0PNJ8/98-222 OS Caenorhabditis brenneri #=GS G0PNJ8/98-222 DE DNA topoisomerase #=GS G0PNJ8/98-222 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis brenneri; #=GS A0A261C990/952-1076 AC A0A261C990 #=GS A0A261C990/952-1076 OS Caenorhabditis latens #=GS A0A261C990/952-1076 DE Uncharacterized protein #=GS A0A261C990/952-1076 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis latens; #=GS A0A261AX82/1030-1154 AC A0A261AX82 #=GS A0A261AX82/1030-1154 OS Caenorhabditis remanei #=GS A0A261AX82/1030-1154 DE Uncharacterized protein #=GS A0A261AX82/1030-1154 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis remanei; #=GS J9W0N6/299-423 AC J9W0N6 #=GS J9W0N6/299-423 OS Cryptococcus neoformans var. grubii H99 #=GS J9W0N6/299-423 DE DNA topoisomerase #=GS J9W0N6/299-423 DR ORG; Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes; Tremellales; Cryptococcaceae; Cryptococcus; Cryptococcus neoformans species complex; Cryptococcus neoformans; Cryptococcus neoformans var. grubii; #=GS A0A2T8I6C2/303-433 AC A0A2T8I6C2 #=GS A0A2T8I6C2/303-433 OS Panicum hallii #=GS A0A2T8I6C2/303-433 DE DNA topoisomerase #=GS A0A2T8I6C2/303-433 DR ORG; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Liliopsida; Petrosaviidae; Poales; Poaceae; Panicoideae; Paniceae; Panicinae; Panicum; Panicum sect. Panicum; Panicum hallii; #=GS A0A0L7KCS6/382-510 AC A0A0L7KCS6 #=GS A0A0L7KCS6/382-510 OS Plasmodium falciparum HB3 #=GS A0A0L7KCS6/382-510 DE DNA topoisomerase #=GS A0A0L7KCS6/382-510 DR ORG; Eukaryota; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania); Plasmodium falciparum; #=GS A0A0L1I9H7/382-510 AC A0A0L1I9H7 #=GS A0A0L1I9H7/382-510 OS Plasmodium falciparum IGH-CR14 #=GS A0A0L1I9H7/382-510 DE DNA topoisomerase #=GS A0A0L1I9H7/382-510 DR ORG; Eukaryota; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania); Plasmodium falciparum; #=GS W7F6L4/382-510 AC W7F6L4 #=GS W7F6L4/382-510 OS Plasmodium falciparum 7G8 #=GS W7F6L4/382-510 DE DNA topoisomerase #=GS W7F6L4/382-510 DR ORG; Eukaryota; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania); Plasmodium falciparum; #=GS W4I7S2/336-464 AC W4I7S2 #=GS W4I7S2/336-464 OS Plasmodium falciparum NF135/5.C10 #=GS W4I7S2/336-464 DE DNA topoisomerase #=GS W4I7S2/336-464 DR ORG; Eukaryota; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania); Plasmodium falciparum; #=GS A0A024WJM3/336-464 AC A0A024WJM3 #=GS A0A024WJM3/336-464 OS Plasmodium falciparum MaliPS096_E11 #=GS A0A024WJM3/336-464 DE DNA topoisomerase #=GS A0A024WJM3/336-464 DR ORG; Eukaryota; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania); Plasmodium falciparum; #=GS A0A024X2W5/336-464 AC A0A024X2W5 #=GS A0A024X2W5/336-464 OS Plasmodium falciparum CAMP/Malaysia #=GS A0A024X2W5/336-464 DE DNA topoisomerase #=GS A0A024X2W5/336-464 DR ORG; Eukaryota; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania); Plasmodium falciparum; #=GS W7JPR7/336-464 AC W7JPR7 #=GS W7JPR7/336-464 OS Plasmodium falciparum NF54 #=GS W7JPR7/336-464 DE DNA topoisomerase #=GS W7JPR7/336-464 DR ORG; Eukaryota; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania); Plasmodium falciparum; #=GS G0MZ90/842-966 AC G0MZ90 #=GS G0MZ90/842-966 OS Caenorhabditis brenneri #=GS G0MZ90/842-966 DE Uncharacterized protein #=GS G0MZ90/842-966 DR ORG; Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis brenneri; #=GS A7F4Y0/294-420 AC A7F4Y0 #=GS A7F4Y0/294-420 OS Sclerotinia sclerotiorum 1980 UF-70 #=GS A7F4Y0/294-420 DE DNA topoisomerase #=GS A7F4Y0/294-420 DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes; Helotiales; Sclerotiniaceae; Sclerotinia; Sclerotinia sclerotiorum; #=GS E1F9F6/289-424 AC E1F9F6 #=GS E1F9F6/289-424 OS Giardia lamblia P15 #=GS E1F9F6/289-424 DE DNA topoisomerase #=GS E1F9F6/289-424 DR ORG; Eukaryota; Diplomonadida; Hexamitidae; Giardiinae; Giardia; Giardia intestinalis; #=GS V6TB61/289-424 AC V6TB61 #=GS V6TB61/289-424 OS Giardia intestinalis #=GS V6TB61/289-424 DE DNA topoisomerase #=GS V6TB61/289-424 DR ORG; Eukaryota; Diplomonadida; Hexamitidae; Giardiinae; Giardia; Giardia intestinalis; #=GS N9UWP2/288-412 AC N9UWP2 #=GS N9UWP2/288-412 OS Entamoeba histolytica HM-1:IMSS-A #=GS N9UWP2/288-412 DE DNA topoisomerase #=GS N9UWP2/288-412 DR ORG; Eukaryota; Entamoebidae; Entamoeba; Entamoeba histolytica; #=GS M7X9I8/288-412 AC M7X9I8 #=GS M7X9I8/288-412 OS Entamoeba histolytica HM-3:IMSS #=GS M7X9I8/288-412 DE DNA topoisomerase #=GS M7X9I8/288-412 DR ORG; Eukaryota; Entamoebidae; Entamoeba; Entamoeba histolytica; #=GS M2RCU9/288-412 AC M2RCU9 #=GS M2RCU9/288-412 OS Entamoeba histolytica KU27 #=GS M2RCU9/288-412 DE DNA topoisomerase #=GS M2RCU9/288-412 DR ORG; Eukaryota; Entamoebidae; Entamoeba; Entamoeba histolytica; #=GS M3TTG7/288-412 AC M3TTG7 #=GS M3TTG7/288-412 OS Entamoeba histolytica HM-1:IMSS-B #=GS M3TTG7/288-412 DE DNA topoisomerase #=GS M3TTG7/288-412 DR ORG; Eukaryota; Entamoebidae; Entamoeba; Entamoeba histolytica; #=GS A4URT1/285-413 AC A4URT1 #=GS A4URT1/285-413 OS Trypanosoma brucei brucei #=GS A4URT1/285-413 DE DNA topoisomerase #=GS A4URT1/285-413 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; Trypanosoma brucei brucei; #=GS A0A3L6TEC4/303-433 AC A0A3L6TEC4 #=GS A0A3L6TEC4/303-433 OS Panicum miliaceum #=GS A0A3L6TEC4/303-433 DE DNA topoisomerase #=GS A0A3L6TEC4/303-433 DR ORG; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Liliopsida; Petrosaviidae; Poales; Poaceae; Panicoideae; Paniceae; Panicinae; Panicum; Panicum miliaceum; #=GS K4A5R4/303-433 AC K4A5R4 #=GS K4A5R4/303-433 OS Setaria italica #=GS K4A5R4/303-433 DE DNA topoisomerase #=GS K4A5R4/303-433 DR ORG; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Liliopsida; Petrosaviidae; Poales; Poaceae; Panicoideae; Paniceae; Cenchrinae; Setaria; Setaria italica; #=GS E6R530/299-423 AC E6R530 #=GS E6R530/299-423 OS Cryptococcus gattii WM276 #=GS E6R530/299-423 DE DNA topoisomerase #=GS E6R530/299-423 DR ORG; Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes; Tremellales; Cryptococcaceae; Cryptococcus; Cryptococcus gattii species complex; Cryptococcus gattii VGI; #=GS A0A0D0VE76/299-423 AC A0A0D0VE76 #=GS A0A0D0VE76/299-423 OS Cryptococcus gattii VGII Ram5 #=GS A0A0D0VE76/299-423 DE DNA topoisomerase #=GS A0A0D0VE76/299-423 DR ORG; Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes; Tremellales; Cryptococcaceae; Cryptococcus; Cryptococcus gattii species complex; Cryptococcus gattii VGII; #=GS A0A226BCU0/299-423 AC A0A226BCU0 #=GS A0A226BCU0/299-423 OS Cryptococcus neoformans var. grubii Bt85 #=GS A0A226BCU0/299-423 DE DNA topoisomerase #=GS A0A226BCU0/299-423 DR ORG; Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes; Tremellales; Cryptococcaceae; Cryptococcus; Cryptococcus neoformans species complex; Cryptococcus neoformans; Cryptococcus neoformans var. grubii; #=GS A0A225XT02/299-423 AC A0A225XT02 #=GS A0A225XT02/299-423 OS Cryptococcus neoformans var. grubii c45 #=GS A0A225XT02/299-423 DE DNA topoisomerase #=GS A0A225XT02/299-423 DR ORG; Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes; Tremellales; Cryptococcaceae; Cryptococcus; Cryptococcus neoformans species complex; Cryptococcus neoformans; Cryptococcus neoformans var. grubii; #=GS Q9HS90/115-240 AC Q9HS90 #=GS Q9HS90/115-240 OS Halobacterium salinarum NRC-1 #=GS Q9HS90/115-240 DE DNA topoisomerase I #=GS Q9HS90/115-240 DR ORG; Archaea; Euryarchaeota; Halobacteria; Halobacteriales; Halobacteriaceae; Halobacterium; Halobacterium salinarum; #=GS D0KTN2/279-405 AC D0KTN2 #=GS D0KTN2/279-405 OS Saccharolobus solfataricus 98/2 #=GS D0KTN2/279-405 DE DNA topoisomerase I #=GS D0KTN2/279-405 DR ORG; Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Saccharolobus; Saccharolobus solfataricus; #=GS A0A0E3JUC3/279-405 AC A0A0E3JUC3 #=GS A0A0E3JUC3/279-405 OS Saccharolobus solfataricus #=GS A0A0E3JUC3/279-405 DE DNA topoisomerase I #=GS A0A0E3JUC3/279-405 DR ORG; Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Saccharolobus; Saccharolobus solfataricus; #=GS C3MPU5/279-405 AC C3MPU5 #=GS C3MPU5/279-405 OS Sulfolobus islandicus L.S.2.15 #=GS C3MPU5/279-405 DE DNA topoisomerase I #=GS C3MPU5/279-405 DR ORG; Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Sulfolobus; Sulfolobus islandicus; #=GS A0A0E3SNS0/282-412 AC A0A0E3SNS0 #=GS A0A0E3SNS0/282-412 OS Methanosarcina barkeri 3 #=GS A0A0E3SNS0/282-412 DE DNA topoisomerase I #=GS A0A0E3SNS0/282-412 DR ORG; Archaea; Euryarchaeota; Methanomicrobia; Methanosarcinales; Methanosarcinaceae; Methanosarcina; Methanosarcina barkeri; #=GS A0A0E3NPL6/316-446 AC A0A0E3NPL6 #=GS A0A0E3NPL6/316-446 OS Methanosarcina sp. WH1 #=GS A0A0E3NPL6/316-446 DE DNA topoisomerase I #=GS A0A0E3NPL6/316-446 DR ORG; Archaea; Euryarchaeota; Methanomicrobia; Methanosarcinales; Methanosarcinaceae; Methanosarcina; Methanosarcina sp. WH1; #=GS A0A1E7GC71/278-408 AC A0A1E7GC71 #=GS A0A1E7GC71/278-408 OS Methanosarcina sp. Ant1 #=GS A0A1E7GC71/278-408 DE DNA topoisomerase #=GS A0A1E7GC71/278-408 DR ORG; Archaea; Euryarchaeota; Methanomicrobia; Methanosarcinales; Methanosarcinaceae; Methanosarcina; Methanosarcina sp. Ant1; #=GF SQ 86 Q9LVP1/303-433 PPYPLNTIELEKRASRYFRLS--------SEHTMKVAEELYQAGFISYPRTETDSFS-SRT---DLRAMVEEQTRHPA--WGSYAQRLLEPE------GGLWRNPANGGHDDKAHPPIHPTKFSSGESNWSR-----DHLNVYELVVRHYLACVSQ Q8IDM7/382-510 KPYPLNTLQMTKLVSIYFKIS--------SKECMMLAEKLYNKGYISYPRTETNYFP-DSM---NLHKIINELRKNDN--FGWYANKLCEEH--------KYQKPRKGKMNDKAHPPIHPVKNMNKSLKVEE-----KEWKLYEFICKHFLAVCSN Q383X7/285-413 PPFPLSTVMLQKLCTAHLRIS--------SDQCMTWAESLYQEGYISYPRTETDSFSFTDN---ELLDIVGSQRRNPE--VSGFVEAMLADP------NRKFRRPLNGGHDDKAHPPIYPTKPM---PAAND-----GRAKLYNLIVRHFLACTSP Q4Q199/286-414 PPVPLATVVMQKLAATHLRIP--------SERCMALAESLYQEGLISYPRTETDSYTFQES---ELLELVRVQISNAD--VAEYATAMLADI------ATRVRPPLRGGRDDKAHPPIHPTKAW---NATQD-----ERGRLYNLIVRHFLASLSP H1UBJ6/163-287 RPCALNTVELMRVASSSLGMS--------PSTTMHVAEALYTQGYISYPRTETTAYS-ANF---DLTGTLKILAGDRK--WGSVVSQVLADG---------IKRPKSG-VDKGDHPPITPMRPNH--GGLSG-----DMSRIYEYVSQHFVATLMK B0R363/281-406 PPAPFNTTQFIRAAGS-LGYS--------AGRAMSIAEDLYTAGYITYPRTDNTVYP-DDL---DERDLLEAFQQTV---FGDDADSLLDQD---------RLSPTSGDEETTDHPPIHPTTDFPDRNQLSE-----DEWAVYELVVRRFFATVAA Q8TMY4/279-403 PPTPFNTTGFISAANS-IGLS--------PANAMRIAESLYTNGYISYPRTDNTVYP-ETL---DLRAQIEIFTEGP---FKEFADALLEKA---------ELVPTRGKKETTDHPPIYPASLAK-ESELKE-----EEWKVYELVVRRFFATFAG W4YMN5/161-285 RPQALNTVELMRVASSSLGMS--------PHHAMQIAERLYIQGYISYPRTETTSYP-ESF---DLKGTLRQQMSAP---WRSEVKVLLDGE---------FTKPRKG-TDVGDHPPITPMRAAN-ESEVGG-----EAWRLYEYIARHFIATVSP W4YTE9/250-374 RPQALNTVELMRVASSSLGMS--------PHHAMQIAERLYIQGYISYPRTETTSYP-ESF---DLKGTLRQQMSAP---WRSEVKVLLDGE---------FTKPRKG-TDVGDHPPITPMRAAN-ESEVGG-----EAWRLYEYIARHFIATVSP Q97ZJ8/279-405 RPSPFNLTDLQIEAGRIYGIS--------PYNVERIAEDLYLDGLISYPRTNSQKIP-STI---SIYNIIKGLENSS---YRKLVDLVRKIT-------GGKYVVKQGIKDDPAHPAIHPTGEAP--KNLPN-----SKFKIYDLIARRFLGSVSA A8B577/289-424 RPLPMNTVALLKAASTVLGLS--------PNSAMALAERLYIAGYISYPRTESTTYP-SGY---NLREIVLALKESSSTRISQCAQNLLPSSKKSSDESVRYTNPRRG-TDQGDHPPIMPTGLIP--HDVSS-----NELSLYNLITKHFLATVSP A7S883/290-407 RPLPLDTVELEKLASRKLHIN--------AKETMKIAEKLYTQGRYSVTGTETTTFN-AVE---SMISYIEFVT--------GFASDVLANG----------PNPRQGSKTDNAHPPIHPTQYT---NNLQG-----NDKRLYEFIVRHFLACCSQ B1L3G6/271-403 PPPPFDGTSLQVEVSAITGLT----PRQIADRTSGIAQKLYEAGLISYIGTESQKYP-KSWKKKDFVDMVKLIASYSP--LKEEAEFVLGDM---------REAAVEGKKDDPAHPTIHVVGVPE--ERLEG-----KYREVYEIIARRNLATLAQ Q8TPW5/278-408 PPNPLNTTEFLKRASKFLGIS--------PEVALEVAEQLYLAGFTSYPRTETNKYA-DDF---DFKTLLFDFARQKE--YKPFAESILSAP----------IVPKNGDKDAHDHPPIHPIRVAA-KGEISAAVTIPHAAEVYDLIARHFLANLMP E3KC11/351-477 KPLPLTTVELQKSGSRLLHLT--------PKTVLDIAEKLYQKGLVSYPRTETDQFD-RDF---DFMGLIEKQMNDSQ--WGDFATRDLKKG-------GGFHTPQNGEKKDITPSTNHPTAHA---NNLTA-----DEKRVYDFITRRYLACCSK A0A0D1C790/307-431 KPYPLTTVELQKSGSRLLRLT--------PKRILDVAESLYQKGFLSYPRTETDEYD-KDL---DFTSLIAKQTADSA--WGNVAQRLLDGA---------FERPRNGKNNDKAHPPIHPTSHA---SGLTG-----DDKRVYDYVTRRFLASCWT A9U3P7/298-436 PPVPLNTVELQKRASRYFRMGYILNYEAVRSQFLQVAEELYQAGFISYPRTETDKFS-ENQ---DLQSIVNEQIGHSA--WGQYAQRLLDPQ------QQLWKQPGDGGHDDKAHPPIHPTRFSEGEGNWTN-----DHARIYELVVRHFLACVSQ A0DGW1/315-442 RPEGINTVSLLKFASSYLGLG--------PQQAMHVAERLYLNGYISYPRTETTAYP-HEF---PTPKIINNLQKYKDPLISEHSKYLKTNG---------HSNPKQG-VDVGDHPPITPTENVP-QNNLYG-----EEKTMYEYVVKMFLAAHSK C4M656/288-412 RPVGLNTVEMLKVASVKLGLG--------PQDTMSIAEKLYTRGYISYPRTESTKYS-SYF---NFTDILNNLQQTNQ--FREKVQLIKQNG---------INIPYNG-EDKGDHPPITPLNYPN--EYLND-----SEKKLFDFITNTFLASIYK A9V1D2/275-399 RPVGLTTTEMQKIASRRFKIA--------PADSLSAAEKLYQQGILSYPRTETNKFD-SSI---DLRPMVEVFAQHSL--YGAFASSLLEGQ---------GPTPRNGNKSDEAHPPIHPTKSV---NNLSG-----REQQIYDLVTRHFLACCSR A0A1D9Q6J0/294-420 KPLPLTTVELQKAASRWLHMN--------SQMAMTAAESLYNKGFISYPRTETDRFD-KGM---NLRALVEKQIQDNR--WGQFAQNLINGG---------FRWPRDGRNDDKAHPPIHPVIYVA-PTALKP-----EEARIYEFVVRRFLACCSE B0ERJ9/288-412 RPIGLNTVEMLKAASIKLGLG--------PQDTMRIAEKLYTRGYISYPRTESTKYS-SYF---NFDDILNNLQETNQ--FREKVQLVKQNG---------INIPRNG-EDKGDHPPITPLNYPN--EYLND-----SEKKLFDFITNTFLASIYK K2G4I6/288-412 RPVGLNTVEMLKVASVKLGLG--------PQETMSIAEKLYTRGYISYPRTESTKYS-SHF---NFTDILNNLQQTNQ--FREKVQLIKQNG---------INIPYNG-EDKGDHPPITPLNYPN--EYLND-----SEKRLFDFITNTFLASIYK A0A3L6S9E6/303-433 PPYPLSTLELQKRASRYFRMS--------SEHTMKVAEELYQAGFISYPRTETDNFS-PNT---DLHAIVREQVEHPV--WGAYAHRLLTPE------ERLWRNPSNGGHDDKAHPPIHPTKFSRGENNWSL-----DHNKLYELVVRHFLACCSQ A0A095C2T0/299-423 KPLPLTTVELQQSGSRLLHMT--------PKRILDLAEKLYQKGIVSYPRTETDQYD-PKF---DFNSLIQKQTLDNQ--WGAYAQKLLDGA---------FQKPRNGRKNDKAHPPIHPTAHA---GNLEG-----DERRVFELITRRFLASCST D2PJZ0/279-405 RPPPFNLTDLQVEAGRIYGIS--------PYNVERIAEDLYLDGLISYPRTNSQKIP-STI---NIYNIIKGLENSS---YRKLVNLVRKIT-------GGKYIVRQGVKDDPAHPAIHPTGESP--KNLPN-----NKFKIYDLIARRFLASVSA A4HPI6/286-414 PPVPLATVIMQKLAATHLRIS--------SERCMTLAESLYQEGLISYPRTETDSYTFQES---ELLELIRLQIANPD--VAEYATAMLADI------AARVRPPLRGGHDDKAHPPIHPTKAW---NATRD-----ERGSLYNLIVRHFLASLSP A0A1G4IB13/285-413 PPFPLSTVMLQKLCTAHLRIS--------SDQCMTWAESLYQEGYISYPRTETDSFSFTDN---ELLDIVGSQRRNPE--VSGFVEAMLADP------NRKFRRPLNGGHDDKAHPPIYPTKPM---PAAND-----GRAKLYNLIVRHFLACTSP A0A0E3NPK1/279-403 PPTPFNTTGFISAANS-IGLS--------PSNAMRIAESLYTNGYISYPRTDNTVYP-DTL---DLRAQIEIFKEGP---FKEYANILLEKA---------ELVPTRGKKETTDHPPIYPASLAK-KTNLKE-----EEWKVYELVVRRFFATFAE A0A0E3WW23/279-403 PPTPFNTTGFISAANS-IGLS--------PANAMRIAEALYTNGYISYPRTDNTVYP-DTL---DLRAQIEIFKEGS---FKEYAESLLEKA---------ELIPTRGKKETTDHPPIFPASLAK-ESDLKE-----EEWKVYELVVRRFFATFAG A0A1E7GDF6/279-403 PPTPFNTTGFISAANA-IGLS--------PSNAMRIAESLYTNGYISYPRTDNTVYP-DTL---DLKAQIEIFKEGP---FREYAIALLEKA---------ELVPTRGKKETTDHPPIFPASLAK-ESDMKE-----DEWKVYELVVRRFFATFAG Q8PSK3/279-403 PPTPFNTTGFISAANS-IGLS--------PANAMRIAESLYTNGYISYPRTDNTVYP-DTL---DLKAQIEIFKEGP---FKEYANTLLEKP---------ELVPTRGKKETTDHPPIFPASLAK-ESDLKE-----DEWKVYELVVRRFFATFAG A4IDA8/286-414 PPVPLATVVMQKLAATHLRIP--------SERCMTLAESLYQEGLISYPRTETDSYTFQES---ELLELVRVQIANAD--VAEYVAAMLADI------ATRVRPPLRGGHDDKAHPPIHPTKAW---NATQD-----ERGRLYNLIVRHFLASLSP A0A088S2H6/286-414 PPVPLATVIMQKLAATHLRIS--------SERCMTLAESLYQEGLISYPRTETDSYTFQES---ELLELIRLQIANPD--VAEYATAMLADI------AARVRPPLRGGHDDKAHPPIHPTKAW---NATRD-----ERGSLYNLIVRHFLASLSP E9AT98/286-414 PPVPLATVVMQKLAATHLRIT--------SERCMTLAESLYQEGLISYPRTETDSYTFQES---ELLELVRVQTANAD--VAEYATAMLADI------ATHVRPPLRGGHDDKAHPPIHPTKAW---NATQD-----ERGRLYNLIVRHFLASLSP D0A8E9/285-413 PPFPLSTVMLQKLCTAHLRIS--------SDQCMTWAESLYQEGYISYPRTETDSFSFTDN---ELLDIVGSQRRNPE--VSGFVEAMLADP------NRKFRRPLNGGHDDKAHPPIYPTKPM---PAAND-----GRAKLYNLIVRHFLACTSP A0A0E3L2I7/316-446 PPNPLNTTEYLKRASKFLGIS--------PEAALEVAEQLYLAGFTSYPRTETNKYA-DDF---DFKSLVFDFARQNE--YKPFAESILSAP----------IVPKNGEKDAHDHPPIHPIRAAA-RREINAAVNIPQAAEVYDLIARHFLANLMP A0A0E3S7M6/278-408 PPNPLNTTEYLKRASKFLGIS--------PEAALEVAEQLYLAGFTSYPRTETNKYA-DDF---DFKSLVFDFARQTE--YKPFAESILSAP----------IVPKNGEKDAHDHPPIHPIRAAA-RREISAAVNIPQAAEAYDLIARHFLANLMP A0A0E3LHR5/302-432 PPNPLNTTEFLKRASKFLGIS--------PELALEVAEQLYLAGFTSYPRTETNKYA-DDF---DFKSLVFDFARQKE--YRPFAESILIAP----------IVPKNGEKDAHDHPPIHPIRAAS-RGEVSSAVNIPQAPEVYDLIARHFLANLMP A0A151LE52/379-507 KPYPLNTLQMTKLVSRYFKIS--------SKECMMIAEKLYNKGYISYPRTETNCFP-DTM---NLHKIINQLRKNDT--FGWYANKLCEEN--------KYHKPRKGKMNDKAHPPIHPVKNMNKILKVEE-----KEWKLYEFICKHFLAVCSN E9BU44/286-414 PPVPLATVVMQKLAATHLRIP--------SERCMTLAESLYQEGLISYPRTETDSYTFQES---ELLELVRVQIANAD--VAEYVAAMLADI------ATRVRPPLRGGHDDKAHPPIHPTKAW---NATQD-----ERGRLYNLIVRHFLASLSP A0A1E1J7S4/286-414 PPVPLATVIMQKLAATHLRIS--------SERCMTLAESLYQEGLISYPRTETDSYTFQES---ELLELIRLQIANPD--VAEYATAMLADI------AARVRPPLRGGHDDKAHPPIHPTKAW---NATRD-----ERGSLYNLIVRHFLASLSP R0GNU4/303-433 PPYPLNTIELEKRASRYFRLS--------SEHTMKVAEELYQAGFISYPRTETDAFS-SRT---DLRAMVEEQTRHPE--WGAYAQRLLEPE------GGLWRNPGNGGHDDKAHPPIHPTKFSSGESNWSR-----DHLNVYELVVRHYLACVSQ D7MQJ2/303-433 PPYPLNTIELEKRASRYFRLS--------SEHTMKVAEELYQAGFISYPRTETDSFS-SRT---DLCAMVEEQRRHPA--WGSYAQRLLEPE------GGLWRNPGNGGHDDKAHPPIHPTKFSSGESNWSR-----DHLNVYELVVRHYLACVSQ M9MAK8/1112-1236 KPYPLTTVELQKSGSRLLRLT--------PKRILDIAESLYQKGFLSYPRTETDQFD-KEF---DFNALIAKQTADGA--WGGVAQRLLDGA---------FERPRNGRNNDKAHPPIHPTSHA---SNLTG-----DDKRVYDYVTRRFLGSCWT A0A1D6JPQ3/302-432 PPYPLSTVELQKRASRYFRMS--------SEHTMKVAEELYQAGFISYPRTETDNFS-PNT---DLHAIVREQVNHPV--WGAYAQRLLNPE------ARLWRNPSNGGHDDKAHPPIHPTKFSEGERNWSP-----DHTRLYEFVVRHFLACCSQ Q5KAU9/299-423 KPLPLTTVELQQSGSRLLHMT--------PKRILDLAEKLYQKGIVSYPRTETDQYD-PKF---DFNSLIQKQTLDNQ--WGAYAQKLLDGA---------FQKPRNGRKNDKAHPPIHPTAHA---GNLEG-----DERRVFELITRRFLASCST A0A368SXG3/303-433 PPYPLSTLELQKRASRYFRMS--------SEHTMKVAEELYQAGFISYPRTETDNFS-PNT---DLHAIVREQVEHPV--WGAYAHRLLTPE------ERLWRNPSNGGHDDKAHPPIHPTKFSRGENNWSP-----DHNRLYELVVRHFLACCSQ A0A1B6QQB9/356-486 PPYPLSTVELQKRASRYFRMS--------SEHTMKVAEELYQAGFISYPRTETDNFS-PNT---DLHAIVREQVNHPV--WGAYAQRLLNPE------ARLWRNPSNGGHDDKAHPPIHPTKFSEGERNWSP-----DHIRLYELVVRHFLACCSQ A0A0D0WB63/299-423 KPLPLTTVELQQSGSRLLHMT--------PKRILDLAEKLYQRGIVSYPRTETDQYD-PKF---DFNSLIQKQTLDNQ--WGAYAQKLLDGA---------FQKPRNGRKNDKAHPPIHPTAHA---GNLDG-----DERRVFELITRRFLASCST A0A0D0UN27/299-423 KPLPLTTVELQQSGSRLLHMT--------PKRILDLAEKLYQKGIVSYPRTETDQYD-PKF---DFNSLIQKQTLDNQ--WGAYAQKLLDSA---------FQKPRNGRKNDKAHPPIHPTAHA---GNLEG-----DERRVFELITRRFLASCSA A0A0D0XTS2/299-423 KPLPLTTVELQQSGSRLLHMT--------PKRILDLAEKLYQKGIVSYPRTETDQYD-PKF---DFNSLIQKQTLDNQ--WGAYAQKLLDGA---------FQKPRNGRKNDKAHPPIHPTSHA---GNLEG-----DERRVFELITRRFLASCST G0PNJ8/98-222 RPCALNTVELMRVASSSLGMS--------PSTTMHVAESLYTQGYISYPRTETTAYP-ANF---DLNGTLKILSGDRK--WGSVVSQVLAEG---------IKRPKSG-VDKGDHPPITPMRANT--GGLSG-----DMARIYEYVSQHFVATLMK A0A261C990/952-1076 RPCALNTVELMRVASSSLGLS--------PSTTMHVAESLYTQGYISYPRTETTAYP-ANF---DLNGTLKILSGDRK--WGSVVSQVLAEG---------IKRPKSG-VDKGDHPPITPMRANT--GNLSG-----DMARIYEYVSQHFVATLMK A0A261AX82/1030-1154 RPCALNTVELMRVASSSLGLS--------PSTTMHVAESLYTQGYISYPRTETTAYP-ANF---DLNGTLKILSGDRK--WGSVVSQVLAEG---------IKRPKSG-VDKGDHPPITPMRANT--GNLSG-----DMARIYEYVSQHFVATLMK J9W0N6/299-423 KPLPLTTVELQQSGSRLLHMT--------PKQILDLAEKLYQKGIVSYPRTETDQYD-PKF---EFNPLIQKQTLDNQ--WGAYAQKLLDGA---------FQRPRNGRKNDKAHPPIHPTAHA---GNLEG-----DERRVFELITRRFLASCSA A0A2T8I6C2/303-433 PPYPLSTLELQKRASRYFRMS--------SEHTMKVAEELYQAGFISYPRTETDNFS-PNT---DLHAIVREQVEHPV--WGAYAHRLLTPE------ERLWRNPSNGGHDDKAHPPIHPTKFSRGENNWSP-----DHNKLYELVVRHFLACCSQ A0A0L7KCS6/382-510 KPYPLNTLQMTKLVSIYFKIS--------SKECMMLAEKLYNKGYISYPRTETNYFP-DSM---NLHKIINELRKNDN--FGWYANKLCEEH--------KYQKPRKGKMNDKAHPPIHPVKNMNKSLKVEE-----KEWKLYEFICKHFLAVCSN A0A0L1I9H7/382-510 KPYPLNTLQMTKLVSIYFKIS--------SKECMMLAEKLYNKGYISYPRTETNYFP-DSM---NLHKIINELRKNDN--FGWYANKLCEEH--------KYQKPRKGKMNDKAHPPIHPVKNMNKSLKVEE-----KEWKLYEFICKHFLAVCSN W7F6L4/382-510 KPYPLNTLQMTKLVSIYFKIS--------SKECMMLAEKLYNKGYISYPRTETNYFP-DSM---NLHKIINELRKNDN--FGWYANKLCEEH--------KYQKPRKGKMNDKAHPPIHPVKNMNKSLKVEE-----KEWKLYEFICKHFLAVCSN W4I7S2/336-464 KPYPLNTLQMTKLVSIYFKIS--------SKECMMLAEKLYNKGYISYPRTETNYFP-DSM---NLHKIINELRKNDN--FGWYANKLCEEH--------KYQKPRKGKMNDKAHPPIHPVKNMNKSLKVEE-----KEWKLYEFICKHFLAVCSN A0A024WJM3/336-464 KPYPLNTLQMTKLVSIYFKIS--------SKECMMLAEKLYNKGYISYPRTETNYFP-DSM---NLHKIINELRKNDN--FGWYANKLCEEH--------KYQKPRKGKMNDKAHPPIHPVKNMNKSLKVEE-----KEWKLYEFICKHFLAVCSN A0A024X2W5/336-464 KPYPLNTLQMTKLVSIYFKIS--------SKECMMLAEKLYNKGYISYPRTETNYFP-DSM---NLHKIINELRKNDN--FGWYANKLCEEH--------KYQKPRKGKMNDKAHPPIHPVKNMNKSLKVEE-----KEWKLYEFICKHFLAVCSN W7JPR7/336-464 KPYPLNTLQMTKLVSIYFKIS--------SKECMMLAEKLYNKGYISYPRTETNYFP-DSM---NLHKIINELRKNDN--FGWYANKLCEEH--------KYQKPRKGKMNDKAHPPIHPVKNMNKSLKVEE-----KEWKLYEFICKHFLAVCSN G0MZ90/842-966 RPCALNTVELMRVASSSLGMS--------PSTTMHVAESLYTQGYISYPRTETTAYP-ANF---DLNGTLKILSGDRK--WGSVVSQVLAEG---------IKRPKSG-VDKGDHPPITPMRANT--GGLSG-----DMARIYEYVSQHFVATLMK A7F4Y0/294-420 KPLPLTTVELQKAASRWLHMN--------SQMAMTAAESLYNKGFISYPRTETDRFD-KGM---NLRALVEKQIQDNR--WGQFAQNLINGG---------FRWPRDGRNDDKAHPPIHPVIYVA-PTALKP-----EEARIYEFVVRRFLACCSE E1F9F6/289-424 RPLPMNTVALLKAASTVLGLS--------PNSAMALAERLYIAGYISYPRTESTTYP-SGY---NLREIVLALKESSSTRISQSAQNLLPSSKKSVDENVRYTNPRKG-TDQGDHPPIMPTGLIP--HGVSG-----DELSLYNLITKHFLATVSP V6TB61/289-424 RPLPMNTVALLKAASTVLGLS--------PNSAMALAERLYIAGYISYPRTESTTYP-SGY---NLREIVLALKESSSTRISQCAQNLLPSSKKSSDESVRYTNPRRG-TDQGDHPPIMPTGLIP--HDVSS-----NELSLYNLITKHFLATVSP N9UWP2/288-412 RPVGLNTVEMLKVASVKLGLG--------PQDTMSIAEKLYTRGYISYPRTESTKYS-SYF---NFTDILNNLQQTNQ--FREKVQLIKQNG---------INIPYNG-EDKGDHPPITPLNYPN--EYLND-----SEKKLFDFITNTFLASIYK M7X9I8/288-412 RPVGLNTVEMLKVASVKLGLG--------PQDTMSIAEKLYTRGYISYPRTESTKYS-SYF---NFTDILNNLQQTNQ--FREKVQLIKQNG---------INIPYNG-EDKGDHPPITPLNYPN--EYLND-----SEKKLFDFITNTFLASIYK M2RCU9/288-412 RPVGLNTVEMLKVASVKLGLG--------PQDTMSIAEKLYTRGYISYPRTESTKYS-SYF---NFTDILNNLQQTNQ--FREKVQLIKQNG---------INIPYNG-EDKGDHPPITPLNYPN--EYLND-----SEKKLFDFITNTFLASIYK M3TTG7/288-412 RPVGLNTVEMLKVASVKLGLG--------PQDTMSIAEKLYTRGYISYPRTESTKYS-SYF---NFTDILNNLQQTNQ--FREKVQLIKQNG---------INIPYNG-EDKGDHPPITPLNYPN--EYLND-----SEKKLFDFITNTFLASIYK A4URT1/285-413 PPFPLSTVMLQKLCTAHLRIS--------SDQCMTWAESLYQEGYISYPRTETDSFSFTDN---ELLDIVGSQRRNPE--VSGFVEAMLADP------NRKFRRPLNGGHDDKAHPPIYPTKPM---PAAND-----GRAKLYNLIVRHFLACTSP A0A3L6TEC4/303-433 PPYPLSTLELQKRASRYFRMS--------SEHTMKVAEELYQAGFISYPRTETDNFS-PNT---DLHAIVREQVEHPV--WGAYAHRLLNPE------ERLWRNPSNGGHDDKAHPPIHPTKFTRGENNWSP-----DHKKLYELVVRHFLACCSQ K4A5R4/303-433 PPYPLSTLELQKRASRYFRMS--------SEHTMKVAEELYQAGFISYPRTETDNFS-PNT---DLHAIVREQVEHPV--WGAYAHRLLTPE------ERLWRNPSNGGHDDKAHPPIHPTKFSRGENNWSP-----DHNRLYELVVRHFLACCSQ E6R530/299-423 KPLPLTTVELQQSGSRLLHMT--------PKRILDLAEKLYQRGIVSYPRTETDQYD-PKF---DFNSLIQKQTLDNQ--WGAYAQKLLDGA---------FQKPRNGRKNDKAHPPIHPTAHA---GNLDG-----DERRVFELITRRFLASCST A0A0D0VE76/299-423 KPLPLTTVELQQSGSRLLHMT--------PKRILDLAEKLYQKGIVSYPRTETDQYD-PKF---DFNSLIQKQTLDNR--WGAYAQKLLDGA---------FQKPRNGRKNDKAHPPIHPTAHA---GNLEG-----DERRVFELITRRFLASCST A0A226BCU0/299-423 KPLPLTTVELQQSGSRLLHMT--------PKRILDLAEKLYQKGIVSYPRTETDQYD-PKF---EFNPLIQKQTLDNQ--WGAYAQKLLDGA---------FQRPRNGRKNDKAHPPIHPTAHA---GNLEG-----DERRVFELITRRFLASCSA A0A225XT02/299-423 KPLPLTTVELQQSGSRLLHMT--------PKRILDLAEKLYQKGIVSYPRTETDQYD-PKF---EFNPLIQKQTLDNQ--WGAYAQKLLDGA---------FQRPRNGRKNDKAHPPIHPTAHA---GNLEG-----DERRVFELITRRFLASCSA Q9HS90/115-240 PPAPFNTTQFIRAAGS-LGYS--------AGRAMSIAEDLYTAGYITYPRTDNTVYP-DDL---DERDLLEAFQQTV---FGDDADSLLDQD---------RLSPTSGDEETTDHPPIHPTTDFPDRNQLSE-----DEWAVYELVVRRFFATVAA D0KTN2/279-405 RPSPFNLTDLQIEAGRIYGIS--------PYNVERIAEDLYLDGLISYPRTNSQKIP-STI---SIYNIIKGLENSS---YRKLVDLVRKIT-------GGKYVVKQGIKDDPAHPAIHPTGEAP--KNLPN-----SKFKIYDLIARRFLGSVSA A0A0E3JUC3/279-405 RPSPFNLTDLQIEAGRIYGIS--------PYNVERIAEDLYLDGLISYPRTNSQKIP-STI---SIYNIIKGLENSS---YRKLVDLVRKIT-------GGKYVVKQGIKDDPAHPAIHPTGEAP--KNLPN-----SKFKIYDLIARRFLGSVSA C3MPU5/279-405 RPPPFNLTDLQVEAGRIYGIS--------PYNVERIAEDLYLDGLISYPRTNSQKIP-STI---NIYNIIKGLENSS---YRKLVNLVRKIT-------GGKYIVRQGVKDDPAHPAIHPTGESP--KNLPN-----NKFKIYDLIARRFLASVSA A0A0E3SNS0/282-412 PPNPLNTTEFLKRASKFLGIS--------PELALEVAEQLYLAGFTSYPRTETNKYA-DDF---DFKSLVFDFARQKE--YKPFAESILIAP----------IIPKNGEKDAHDHPPIHPIRAAS-RGEISSAVNIPQAPEVYDLIARHFLANLMP A0A0E3NPL6/316-446 PPNPLNTTEYLKRASKFLGIS--------PEAALEVAEQLYLAGFTSYPRTETNKYA-DDF---DFKSLVFDFARQNE--YKPFAESILSAP----------IVPKNGEKDAHDHPPIHPIRAAA-RREINAAVNIPQAAEVYDLIARHFLANLMP A0A1E7GC71/278-408 PPNPLNTTEFLKRASKFLGIS--------PELALEVAEQLYLAGFTSYPRTDTNKYA-DDF---DFKSLLFDFARQKE--YRPFAESILIAP----------IVPKNGEKDAHDHPPIHPIRAAS-RGEVSSAVNIPQAPEVYDLIARHFLANLMP #=GC scorecons 593775855645366326456000000006434635984994495788889764364033300055335633433332004434643553330000000002338349246545888858543310034444000004425686674658784453 #=GC scorecons_70 _*_**_*_______*__________________*__**_**__*_********__*____________________________*___________________*__*__*___****_*______________________**_*_*_***____ #=GC scorecons_80 _*__*_*_____________________________**_**__*__******____________________________________________________*__*______****_*______________________*__*___***____ #=GC scorecons_90 _*__________________________________**_**__*__*****________________________________________________________*______**_*_*_____________________________*_*____ //