# STOCKHOLM 1.0 #=GF ID 1.10.274.30/FF/000007 #=GF DE Male-specific lethal 3 #=GF AC 1.10.274.30/FF/000007 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 86.931 #=GS P50536/195-323_416-496 AC P50536 #=GS P50536/195-323_416-496 OS Drosophila melanogaster #=GS P50536/195-323_416-496 DE Protein male-specific lethal-3 #=GS P50536/195-323_416-496 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila melanogaster; #=GS P50536/195-323_416-496 DR GO; GO:0000228; GO:0000805; GO:0003682; GO:0003723; GO:0003729; GO:0005700; GO:0007549; GO:0009047; GO:0010369; GO:0016456; GO:0031936; GO:0035064; GO:0035206; GO:0072487; #=GS Q9NBL2/247-376_461-534 AC Q9NBL2 #=GS Q9NBL2/247-376_461-534 OS Drosophila virilis #=GS Q9NBL2/247-376_461-534 DE Protein male-specific lethal-3 #=GS Q9NBL2/247-376_461-534 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Drosophila; virilis group; Drosophila virilis; #=GS Q9NBL2/247-376_461-534 DR GO; GO:0000805; GO:0003682; GO:0007549; #=GS E9G1D7/157-383 AC E9G1D7 #=GS E9G1D7/157-383 OS Daphnia pulex #=GS E9G1D7/157-383 DE Uncharacterized protein #=GS E9G1D7/157-383 DR ORG; Eukaryota; Metazoa; Arthropoda; Crustacea; Branchiopoda; Phyllopoda; Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia; Daphnia pulex; #=GS D6X510/143-264_358-427 AC D6X510 #=GS D6X510/143-264_358-427 OS Tribolium castaneum #=GS D6X510/143-264_358-427 DE Male-specific lethal 3 homolog-like Protein #=GS D6X510/143-264_358-427 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Coleoptera; Polyphaga; Cucujiformia; Tenebrionoidea; Tenebrionidae; Tribolium; Tribolium castaneum; #=GS Q7PYF7/165-290_419-505 AC Q7PYF7 #=GS Q7PYF7/165-290_419-505 OS Anopheles gambiae #=GS Q7PYF7/165-290_419-505 DE AGAP001917-PA #=GS Q7PYF7/165-290_419-505 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicomorpha; Culicoidea; Culicidae; Anophelinae; Anopheles; Cellia; Anopheles gambiae; #=GS B4HV20/195-323_416-496 AC B4HV20 #=GS B4HV20/195-323_416-496 OS Drosophila sechellia #=GS B4HV20/195-323_416-496 DE GM13789 #=GS B4HV20/195-323_416-496 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila sechellia; #=GS A8BPB2/195-323_416-496 AC A8BPB2 #=GS A8BPB2/195-323_416-496 OS Drosophila simulans #=GS A8BPB2/195-323_416-496 DE GD13090 #=GS A8BPB2/195-323_416-496 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila simulans; #=GS B3NFI3/195-315_416-497 AC B3NFI3 #=GS B3NFI3/195-315_416-497 OS Drosophila erecta #=GS B3NFI3/195-315_416-497 DE Uncharacterized protein #=GS B3NFI3/195-315_416-497 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila erecta; #=GS B4PK25/195-315_416-496 AC B4PK25 #=GS B4PK25/195-315_416-496 OS Drosophila yakuba #=GS B4PK25/195-315_416-496 DE Uncharacterized protein #=GS B4PK25/195-315_416-496 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila yakuba; #=GS A8IL10/195-323_416-496 AC A8IL10 #=GS A8IL10/195-323_416-496 OS Drosophila simulans #=GS A8IL10/195-323_416-496 DE Male-specific lethal 3 #=GS A8IL10/195-323_416-496 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila simulans; #=GS B4LHK5/205-334_419-493 AC B4LHK5 #=GS B4LHK5/205-334_419-493 OS Drosophila virilis #=GS B4LHK5/205-334_419-493 DE Male lethal 3 #=GS B4LHK5/205-334_419-493 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Drosophila; virilis group; Drosophila virilis; #=GF SQ 11 P50536/195-323_416-496 --PQEDRIMMRVSERLRELIEYDRNMIKVLGKQHALPARVPIVTIMENFVKQQAVELAISI---KQDSSRAR-NTQS-RNARMEREYDRVMSTVCMLKEVVDGLRIYFEFHVDDHLLYTEEKEYVHNY------LTDDNMRN--N-----ETFKWRLLSAESPPE---KSMVFGAPHLVRLMIKMPMFLNASPISNKKLEDLLPHLDAFINYLENHREWFDRENFVNSTALPQ- Q9NBL2/247-376_461-534 -IHQEDRVMLRISERLREYMEYDYNMVCKLEKQHALPARTPIVTILENFVKQRAVELAIGI---KQDSSRAR-NTLS-RNARMEREYDRVMSIVCMLKEVVDGLRIYFEFHLEDHLLYREEKDYALGF------LTDNNMKN----------FSWSLLSEESPPE---KSIIFGAPHLARMLVLLPECLNASPISNEKLVDLLPHLDSFINYLENHKEWFDKQNYLDPL----- E9G1D7/157-383 --NENAIVVFNIPDAIKQLLEEDGIKIKSRKKLLKLPCHVSVTTVLDGFLRHYASTFTSKN--SEKNRVSQRTNSTSSNTSSNAGDSATIATQLTLCKEVIDGLRVSFDFLIGSILLYAEERPQYEQMKNKHDIRINRGPSKVAEHPLTQDNFQWRVLPDSNNIQNFLPCTVYGVVHLCRLLVKLPEVIQKMQLSEEKRRIVTNFSELLLQYIDKHQIHVSESDYVAATKF--- D6X510/143-264_358-427 SSIEEETVPIELTPELRACLEQDYCLINTKNKLVKLPAEPNVVTILENYWRHYANGQISDL----NEKTSQR-HRYP-FNNTQRRRPEDVQRNLNICSEVLDGIRLYFDYTVNDLLLYKCEQGQIE-------------TKHVYN---------------QQPPP---PCLVYGAIHLTRLFVKLPELLNAATIDEKKWTTLLQHMDTFIDYLNEHREWFGEKFYIDRQ----- Q7PYF7/165-290_419-505 -SHEEEKVYLQAGSKFRKHLDLDQHLIVSGTMLVELPAKQPVVTILEDFVRYYTIRQLFECGHQEQTKSRRR-NSSAVRTEHKVRDYEQIRTNVELCKEVADGLRVYFDFTLQDYLLYPQEKPQAQ--------IVSREAKEVLD-----DVFRWRILPSNAPAE---PSMIYGAVHLARLIVKLPEFLSATAMADEKLKLLLKFLDIFAEFIEEHEEWFGKQFYFSLKDN--- B4HV20/195-323_416-496 --PQEDRIMMRVSERLRELIEYDRNMVKVLGKQHALPARVPIVTIMENFVKQQAVELAISI---KQDSSRAR-NTQS-RNARMEREYDRVMSTVCMLKEVVDGLRIYFEFHVDDHLLYKEEKEYVHNY------LTDANMRN--S-----ETFKWRLLSAESPPE---KSMVFGAPHLVRLMIKMPMFLNASPISNKKLEDLLPHLDAFINYLENHREWFDRENYVNSTALPQ- A8BPB2/195-323_416-496 --PQEDRIMMRVSERLRELIEYDRNMVKVLGKQHALPARVPIVTIMENFVKQQAVELAISI---KQDSSRAR-NTQS-RNARMEREYDRVMSTVCMLKEVVDGLRIYFEFHVDDHLLYKEEKEYVHNY------LTDANMRN--S-----ETFKWRLLSAESPPE---KSMVFGAPHLVRLMIKMPMFLNASPISNKKLEDLLPHLDAFINYLENHREWFDRENYVNSTALPQ- B3NFI3/195-315_416-497 --PQEDRVMMRVSERLRELMEYDRNMVKVLGKQHALPARVPIVTIMENFVKQQAVELAISI---KQDSSRAR-NTQS-RNARMEREYDRVMSSVCMLKEVVDGLRIYFEFHVDDHLLYKEEKEYVHNY----------------Y-----ETFKWRLLSAESPPE---KSMVFGAPHLVRLMIKMPMFLNASPISNKKLEDLLPHLDAFINYLENHREWFDKDNYVNSTALPQE B4PK25/195-315_416-496 --PQEDRVMMRVSERLRELIEYDRNMVKVLGKQHALPARVPIVTIMENFVKQQAVELAISI---KQDSSRAR-NTQS-RNARMEREYDRVMSSVCMLKEVVDGLRIYFEFHVDDHLLYKEEKEYVHNY----------------H-----ETFKWRLLSAESPPE---KSMVFGAPHLVRLMIKMPMFLNASPISNKKLEDLLPLLDAFINYLENHREWFDKDNYVNSTALPQ- A8IL10/195-323_416-496 --PQEDRIMMRVSERLRELIEYDRNMVKVLGKQHALPARVPIVTIMENFVKQQAVELAISI---KQDSSRAR-NTQS-RNARMEREYDRVMSTVCMLKEVVDGLRIYFEFHVDDHLLYKEEKEYVHNY------LTDANMRN--S-----ETFKWRLLSAESPPE---KSMVFGAPHLVRLMIKMPMFLNASPISNKKLEDLLPHLDAFINYLENHREWFDRENYVNSTALPQ- B4LHK5/205-334_419-493 -IHQEDRVMLRISERLREYMEYDYNMVCKLEKQHALPARTPIVTILENFVKQRAVELAIGI---KQDSSRAR-NTLS-RNARMEREYDRVMSIVCMLKEVVDGLRIYFEFHLEDHLLYREEKDYALGF------LTDNNMKN----------FSWSLLSEESPPE---KSIIFGAPHLARMLVLLPECLNASPISNEKLVDLLPHLDSFINYLENHKEWFDKQNYVDPLI---- #=GC scorecons 003675474545544674458393456433374449965456797676856547444443400046545549075360564444755547453646479959979669684647499945964544220000002221223310200000326364464344655000465779749949757669447564466559433764557476586659566755448543422110 #=GC scorecons_70 ___**__*_______**___*_*___*____*___***___******_*_*__*_________________*_*_____*____*____*___*___***_****_****___*_***__**______________________________*_*__*____*______*_****_**_**_****__*_*__*___*___**___*_*__***_*_***____*_________ #=GC scorecons_80 ____*__*________*___*_*____________**______**_*_*____*_________________*_*_______________*________**_****__*_*_____***__*__________________________________________________****_**_**____*__*________*___*____*_*__*___*________*_________ #=GC scorecons_90 ______________________*____________**______*____*______________________*__________________________**_**_*__*_*_____***__*____________________________________________________*__**_*_____*___________*_____________*___*________*_________ //