# STOCKHOLM 1.0
#=GF ID 1.10.268.10/FF/000010
#=GF DE DNA topoisomerase 2
#=GF AC 1.10.268.10/FF/000010
#=GF TP FunFam
#=GF DR CATH: v4.3
#=GF DR DOPS: 34.440
#=GS P12531/977-1114      AC P12531
#=GS P12531/977-1114      OS Trypanosoma brucei brucei
#=GS P12531/977-1114      DE DNA topoisomerase 2
#=GS P12531/977-1114      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; Trypanosoma brucei brucei; 
#=GS P12531/977-1114      DR GO; GO:0003918; GO:0005634; GO:0005739; GO:0006265; GO:0020023; 
#=GS P12531/977-1114      DR EC; 5.6.2.3; 
#=GS Q4QF53/981-1114      AC Q4QF53
#=GS Q4QF53/981-1114      OS Leishmania major
#=GS Q4QF53/981-1114      DE DNA topoisomerase 2
#=GS Q4QF53/981-1114      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania major species complex; Leishmania major; 
#=GS Q4QF53/981-1114      DR GO; GO:0020023; 
#=GS O61078/981-1114      AC O61078
#=GS O61078/981-1114      OS Leishmania chagasi
#=GS O61078/981-1114      DE DNA topoisomerase 2
#=GS O61078/981-1114      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania chagasi; 
#=GS O61078/981-1114      DR EC; 5.6.2.3; 
#=GS A0A1G4I7P1/977-1114  AC A0A1G4I7P1
#=GS A0A1G4I7P1/977-1114  OS Trypanosoma equiperdum
#=GS A0A1G4I7P1/977-1114  DE DNA topoisomerase 2
#=GS A0A1G4I7P1/977-1114  DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma equiperdum; 
#=GS A0A3P3Z213/982-1115  AC A0A3P3Z213
#=GS A0A3P3Z213/982-1115  OS Leishmania braziliensis MHOM/BR/75/M2904
#=GS A0A3P3Z213/982-1115  DE DNA topoisomerase 2
#=GS A0A3P3Z213/982-1115  DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania braziliensis species complex; Leishmania braziliensis; 
#=GS A0A1E1IS39/982-1115  AC A0A1E1IS39
#=GS A0A1E1IS39/982-1115  OS Leishmania guyanensis
#=GS A0A1E1IS39/982-1115  DE DNA topoisomerase 2
#=GS A0A1E1IS39/982-1115  DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania guyanensis species complex; Leishmania guyanensis; 
#=GS E9AQC1/981-1114      AC E9AQC1
#=GS E9AQC1/981-1114      OS Leishmania mexicana MHOM/GT/2001/U1103
#=GS E9AQC1/981-1114      DE DNA topoisomerase 2
#=GS E9AQC1/981-1114      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania mexicana species complex; Leishmania mexicana; 
#=GS A4HWL4/981-1114      AC A4HWL4
#=GS A4HWL4/981-1114      OS Leishmania infantum
#=GS A4HWL4/981-1114      DE DNA topoisomerase 2
#=GS A4HWL4/981-1114      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania infantum; 
#=GS A0A088RLN4/982-1115  AC A0A088RLN4
#=GS A0A088RLN4/982-1115  OS Leishmania panamensis
#=GS A0A088RLN4/982-1115  DE DNA topoisomerase 2
#=GS A0A088RLN4/982-1115  DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania guyanensis species complex; Leishmania panamensis; 
#=GS E9BCH0/981-1114      AC E9BCH0
#=GS E9BCH0/981-1114      OS Leishmania donovani BPK282A1
#=GS E9BCH0/981-1114      DE DNA topoisomerase 2
#=GS E9BCH0/981-1114      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania donovani; 
#=GS Q38EZ6/977-1114      AC Q38EZ6
#=GS Q38EZ6/977-1114      OS Trypanosoma brucei brucei TREU927
#=GS Q38EZ6/977-1114      DE DNA topoisomerase 2
#=GS Q38EZ6/977-1114      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; Trypanosoma brucei brucei; 
#=GS A4H891/982-1115      AC A4H891
#=GS A4H891/982-1115      OS Leishmania braziliensis
#=GS A4H891/982-1115      DE DNA topoisomerase 2
#=GS A4H891/982-1115      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Viannia; Leishmania braziliensis species complex; Leishmania braziliensis; 
#=GF SQ 12
P12531/977-1114              LTPVLQWHYDRRLDLYKKRRQRNLTLLEQELAREKSTLKFVQHFGAGHIDFANATEATLEKVCSKLGLVRVDDSFDYILRKPITFYTKTSFENLLKKIAETERRIEALKKTTPVQLWLGELDQFDRFFQDHEKKMVEA
Q4QF53/981-1114              LSPVLQWHYDRRLDLYKRRRTRKIGLMEMDLARLQSTRKFVEHFRQGQIDFLNATDDTLHKTCVKLGLVRVDESFDYILKKPITFFTRTSTEKLQADIAKTQAQIEELKRTTPVKMWLTELDKFDKTFQEYERV----
O61078/981-1114              LSPVLQWHYDRRLDLYKRRRTRKIGLMKMDLARLQSTRKFVEHFRQGQIDFLNATDDTLHKTCVKLGLVRVDESFDYILKKPITFFTRTSTEKLQADIAKTQAQIEELKRTTPVKMWLTELDKFDKTFQEYERV----
A0A1G4I7P1/977-1114          LTPVLQWHYDRRLDLYKKRRQRNLMLLEQELAREKSTLKFVQHFRAGHIDFANATEATLEKVCSKLGLVRVDDSFDYILRKPITFYTKTSFENLLKKIAETERRIEALKKTTPVQLWLGELDQFDRFFQDHEKKMVEA
A0A3P3Z213/982-1115          -APVLQWHYDRRLDLYKRRRTRKIGLMEMDLARLKSTRKFVEHFRQGQIDFLNATDDTLTKTCVKLGLVRVDESFDYILKKPITFFTRTSTEKLQEDIAKTQAQIEELKRTTPVRMWLTELDKFDKTFQEYERVL---
A0A1E1IS39/982-1115          -APVLQWHYDRRLDLYKRRRTRKIGLMEMDLARLKSTRKFVEHFRQGQIDFLNATDDTLTKTCVKLGLVRVDESFDYILKKPITFFTRTSTEKLQEDIAKTQAQIEELKRTTPVRMWLTELDKFDKTFQEYERVL---
E9AQC1/981-1114              LSPVLQWHYDRRLDLYKRRRTRKIGLMEMDLARLQSTRKFVEHFRQGQIDFLNATDDTLHKTCVKLGLVRVDESFDYILKKPITFFTRTSTEKLQADIAKTQAQIEELKRTTPVKMWLTELDKFDKTFQEYERV----
A4HWL4/981-1114              LSPVLQWHYDRRLDLYKRRRTRKIGLMEMDLARLQSTRKFVEHFRQGQIDFLNATDDTLHKTCVKLGLVRVDESFDYILKKPITFFTRTSTEKLQADIAKTQAQIEELKRTTPVKMWLTELDKFDKTFQEYERV----
A0A088RLN4/982-1115          -APVLQWHYDRRLDLYKRRRTRKIGLMEMDLARLKSTRKFVEHFRQGQIDFLNATDDTLTKTCVKLGLVRVDESFDYILKKPITFFTRTSTEKLQEDIAKTQAQIEELKRTTPVRMWLTELDKFDKTFQEYERVL---
E9BCH0/981-1114              LSPVLQWHYDRRLDLYKRRRTRKIGLMEMDLARLQSTRKFVEHFRQGQIDFLNATDDTLHKTCVKLGLVRVDESFDYILKKPITFFTRTSTEKLQADIAKTQAQIEELKRTTPVKMWLTELDKFDKTFQEYERV----
Q38EZ6/977-1114              LTPVLQWHYDRRLDLYKKRRQRNLMLLEQELAREKSTLKFVQHFRAGHIDFANATEATLEKVCSKLGLVRVDDSFDYILRKPITFYTKTSFENLLKKIAETERRIEALKKTTPVQLWLGELDQFDRFFQDHEKKMVEA
A4H891/982-1115              -APVLQWHYDRRLDLYKRRRTRKIGLMEMDLARLKSTRKFVEHFRQGQIDFLNATDDTLTKTCVKLGLVRVDESFDYILKKPITFFTRTSTEKLQEDIAKTQAQIEELKRTTPVRMWLTELDKFDKTFQEYERVL---
#=GC scorecons               459999999999999997995966496857999469949996997596999599975994959599999999799999979999979799596954599696569959979999569959996997599779742111
#=GC scorecons_70            __******************_*_*_***_****_***_*******_*****_****_**_*_*_**************************_*_*___**_**_***_*******_***_*******_******_____
#=GC scorecons_80            __***************_**_*___*_*__***__**_***_***_*_***_***__**_*_*_********_******_*******_**_*_*___**_*___**_**_****__**_***_**__**__*______
#=GC scorecons_90            __***************_**_*___*_*__***__**_***_**__*_***_***__**_*_*_********_******_*****_*_**_*_*___**_*___**_**_****__**_***_**__**__*______
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