# STOCKHOLM 1.0 #=GF ID 1.10.245.10/FF/000005 #=GF DE E3 ubiquitin-protein ligase Mdm2 #=GF AC 1.10.245.10/FF/000005 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 17.797 #=GS 5j7fD00/1-125 AC Q00987 #=GS 5j7fD00/1-125 OS Homo sapiens #=GS 5j7fD00/1-125 DE E3 ubiquitin-protein ligase Mdm2 #=GS 5j7fD00/1-125 DR CATH; 5j7f; D:12-110; #=GS 5j7fD00/1-125 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Homo; Homo sapiens; #=GS A7UKY0/1-115 AC A7UKY0 #=GS A7UKY0/1-115 OS Homo sapiens #=GS A7UKY0/1-115 DE E3 ubiquitin-protein ligase Mdm2 #=GS A7UKY0/1-115 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Homo; Homo sapiens; #=GS A7UKY0/1-115 DR GO; GO:0005515; GO:0005730; GO:0006511; #=GS 5j7fC00/1-125 AC Q00987 #=GS 5j7fC00/1-125 OS Homo sapiens #=GS 5j7fC00/1-125 DE E3 ubiquitin-protein ligase Mdm2 #=GS 5j7fC00/1-125 DR CATH; 5j7f; C:11-111; #=GS 5j7fC00/1-125 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Homo; Homo sapiens; #=GS 5j7fB00/1-125 AC Q00987 #=GS 5j7fB00/1-125 OS Homo sapiens #=GS 5j7fB00/1-125 DE E3 ubiquitin-protein ligase Mdm2 #=GS 5j7fB00/1-125 DR CATH; 5j7f; B:12-114; #=GS 5j7fB00/1-125 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Homo; Homo sapiens; #=GS 5j7fA00/1-125 AC Q00987 #=GS 5j7fA00/1-125 OS Homo sapiens #=GS 5j7fA00/1-125 DE E3 ubiquitin-protein ligase Mdm2 #=GS 5j7fA00/1-125 DR CATH; 5j7f; A:11-111; #=GS 5j7fA00/1-125 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Homo; Homo sapiens; #=GS 2lzgA00/1-125 AC Q00987 #=GS 2lzgA00/1-125 OS Homo sapiens #=GS 2lzgA00/1-125 DE E3 ubiquitin-protein ligase Mdm2 #=GS 2lzgA00/1-125 DR CATH; 2lzg; A:1-125; #=GS 2lzgA00/1-125 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Homo; Homo sapiens; #=GS E7EPE2/1-52_84-147 AC E7EPE2 #=GS E7EPE2/1-52_84-147 OS Homo sapiens #=GS E7EPE2/1-52_84-147 DE E3 ubiquitin-protein ligase Mdm2 #=GS E7EPE2/1-52_84-147 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Homo; Homo sapiens; #=GS F5H4Q8/1-116 AC F5H4Q8 #=GS F5H4Q8/1-116 OS Homo sapiens #=GS F5H4Q8/1-116 DE E3 ubiquitin-protein ligase Mdm2 #=GS F5H4Q8/1-116 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Homo; Homo sapiens; #=GS A7UKX8/1-115 AC A7UKX8 #=GS A7UKX8/1-115 OS Homo sapiens #=GS A7UKX8/1-115 DE E3 ubiquitin-protein ligase Mdm2 #=GS A7UKX8/1-115 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Homo; Homo sapiens; #=GS Q8NDW2/1-112 AC Q8NDW2 #=GS Q8NDW2/1-112 OS Homo sapiens #=GS Q8NDW2/1-112 DE p53-binding protein #=GS Q8NDW2/1-112 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Homo; Homo sapiens; #=GS Q96DS4/1-115 AC Q96DS4 #=GS Q96DS4/1-115 OS Homo sapiens #=GS Q96DS4/1-115 DE MDM2 variant FB26 #=GS Q96DS4/1-115 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Homo; Homo sapiens; #=GS I6T4L8/1-113 AC I6T4L8 #=GS I6T4L8/1-113 OS Homo sapiens #=GS I6T4L8/1-113 DE HDM2 transcript variant MYO-25 #=GS I6T4L8/1-113 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Homo; Homo sapiens; #=GS A0A2R8N6G5/1-115 AC A0A2R8N6G5 #=GS A0A2R8N6G5/1-115 OS Callithrix jacchus #=GS A0A2R8N6G5/1-115 DE Uncharacterized protein #=GS A0A2R8N6G5/1-115 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Platyrrhini; Cebidae; Callitrichinae; Callithrix; Callithrix; Callithrix jacchus; #=GS A0A2K5DCT2/1-113 AC A0A2K5DCT2 #=GS A0A2K5DCT2/1-113 OS Aotus nancymaae #=GS A0A2K5DCT2/1-113 DE Uncharacterized protein #=GS A0A2K5DCT2/1-113 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Platyrrhini; Aotidae; Aotus; Aotus nancymaae; #=GS A0A2J8K4T8/1-115 AC A0A2J8K4T8 #=GS A0A2J8K4T8/1-115 OS Pan troglodytes #=GS A0A2J8K4T8/1-115 DE MDM2 isoform 30 #=GS A0A2J8K4T8/1-115 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Pan; Pan troglodytes; #=GS A0A2R8MAM8/1-113 AC A0A2R8MAM8 #=GS A0A2R8MAM8/1-113 OS Callithrix jacchus #=GS A0A2R8MAM8/1-113 DE Uncharacterized protein #=GS A0A2R8MAM8/1-113 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Platyrrhini; Cebidae; Callitrichinae; Callithrix; Callithrix; Callithrix jacchus; #=GS A0A2R8MVK9/1-114 AC A0A2R8MVK9 #=GS A0A2R8MVK9/1-114 OS Callithrix jacchus #=GS A0A2R8MVK9/1-114 DE Uncharacterized protein #=GS A0A2R8MVK9/1-114 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Platyrrhini; Cebidae; Callitrichinae; Callithrix; Callithrix; Callithrix jacchus; #=GS F7C214/1-115 AC F7C214 #=GS F7C214/1-115 OS Callithrix jacchus #=GS F7C214/1-115 DE Uncharacterized protein #=GS F7C214/1-115 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Platyrrhini; Cebidae; Callitrichinae; Callithrix; Callithrix; Callithrix jacchus; #=GS A0A2R8MJ94/1-115 AC A0A2R8MJ94 #=GS A0A2R8MJ94/1-115 OS Callithrix jacchus #=GS A0A2R8MJ94/1-115 DE Uncharacterized protein #=GS A0A2R8MJ94/1-115 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Platyrrhini; Cebidae; Callitrichinae; Callithrix; Callithrix; Callithrix jacchus; #=GS A0A2R8M2L2/1-115 AC A0A2R8M2L2 #=GS A0A2R8M2L2/1-115 OS Callithrix jacchus #=GS A0A2R8M2L2/1-115 DE Uncharacterized protein #=GS A0A2R8M2L2/1-115 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Platyrrhini; Cebidae; Callitrichinae; Callithrix; Callithrix; Callithrix jacchus; #=GS A0A2J8K4W7/1-116 AC A0A2J8K4W7 #=GS A0A2J8K4W7/1-116 OS Pan troglodytes #=GS A0A2J8K4W7/1-116 DE MDM2 isoform 19 #=GS A0A2J8K4W7/1-116 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Pan; Pan troglodytes; #=GS A0A2K5DCL9/1-114 AC A0A2K5DCL9 #=GS A0A2K5DCL9/1-114 OS Aotus nancymaae #=GS A0A2K5DCL9/1-114 DE Uncharacterized protein #=GS A0A2K5DCL9/1-114 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Platyrrhini; Aotidae; Aotus; Aotus nancymaae; #=GS A0A2R8MW03/1-114 AC A0A2R8MW03 #=GS A0A2R8MW03/1-114 OS Callithrix jacchus #=GS A0A2R8MW03/1-114 DE Uncharacterized protein #=GS A0A2R8MW03/1-114 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Platyrrhini; Cebidae; Callitrichinae; Callithrix; Callithrix; Callithrix jacchus; #=GS A0A2R8NFN7/1-114 AC A0A2R8NFN7 #=GS A0A2R8NFN7/1-114 OS Callithrix jacchus #=GS A0A2R8NFN7/1-114 DE Uncharacterized protein #=GS A0A2R8NFN7/1-114 DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Platyrrhini; Cebidae; Callitrichinae; Callithrix; Callithrix; Callithrix jacchus; #=GF SQ 24 5j7fD00/1-125 MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQESSDSGTSVSEN A7UKY0/1-115 MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQES---------- 5j7fC00/1-125 MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQESSDSGTSVSEN 5j7fB00/1-125 MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQESSDSGTSVSEN 5j7fA00/1-125 MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQESSDSGTSVSEN 2lzgA00/1-125 MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQESSDSGTSVSEN E7EPE2/1-52_84-147 MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQESS--------- F5H4Q8/1-116 MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQESS--------- A7UKX8/1-115 MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQES---------- Q8NDW2/1-112 MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQ------------- Q96DS4/1-115 MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQES---------- I6T4L8/1-113 MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQ------------ A0A2R8N6G5/1-115 MCNTNMSVTTDGAVTTSQIPASEQEIPVRPKPLLLKLLKSVGAQKDIYTTKEVLFYLGRYIMNKQLYDEKQQHIVYCSNDLLGNLFGVPSFSLKEHRKIYTMIYKNLVVVNQQES---------- A0A2K5DCT2/1-113 MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMNKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQ------------ A0A2J8K4T8/1-115 MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQES---------- A0A2R8MAM8/1-113 MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMNKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQ------------ A0A2R8MVK9/1-114 MCNTNMSVTTDGAVTTSQIPASEQEIPVRPKPLLLKLLKSVGAQKDIYTTKEVLFYLGRYIMNKQLYDEKQQHIVYCSNDLLGNLFGVPSFSLKEHRKIYTMIYKNLVVVNQQE----------- F7C214/1-115 MCNTNMSVTTDGAVTTSQIPASEQEIPVRPKPLLLKLLKSVGAQKDIYTTKEVLFYLGRYIMNKQLYDEKQQHIVYCSNDLLGNLFGVPSFSLKEHRKIYTMIYKNLVVVNQQES---------- A0A2R8MJ94/1-115 MCNTNMSVTTDGAVTTSQIPASEQEIPVRPKPLLLKLLKSVGAQKDIYTTKEVLFYLGRYIMNKQLYDEKQQHIVYCSNDLLGNLFGVPSFSLKEHRKIYTMIYKNLVVVNQQES---------- A0A2R8M2L2/1-115 MCNTNMSVTTDGAVTTSQIPASEQEIPVRPKPLLLKLLKSVGAQKDIYTTKEVLFYLGRYIMNKQLYDEKQQHIVYCSNDLLGNLFGVPSFSLKEHRKIYTMIYKNLVVVNQQES---------- A0A2J8K4W7/1-116 MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQESS--------- A0A2K5DCL9/1-114 MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMNKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQE----------- A0A2R8MW03/1-114 MCNTNMSVTTDGAVTTSQIPASEQEIPVRPKPLLLKLLKSVGAQKDIYTTKEVLFYLGRYIMNKQLYDEKQQHIVYCSNDLLGNLFGVPSFSLKEHRKIYTMIYKNLVVVNQQE----------- A0A2R8NFN7/1-114 MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMNKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQE----------- #=GC scorecons 99999999699999999999999996699999999999999999996996999999996999696999999999999999999699999999699999999999799999998641000000000 #=GC scorecons_70 **************************************************************_***************************************************___________ #=GC scorecons_80 ********_****************__*******************_**_********_***_*_******************_********_********************____________ #=GC scorecons_90 ********_****************__*******************_**_********_***_*_******************_********_***********_********____________ //