# STOCKHOLM 1.0
#=GF ID 1.10.1410.10/FF/000027
#=GF DE Topoisomerase-related function protein-like protein
#=GF AC 1.10.1410.10/FF/000027
#=GF TP FunFam
#=GF DR CATH: v4.3
#=GF DR DOPS: 85.901
#=GS Q57VP5/319-336_447-616              AC Q57VP5
#=GS Q57VP5/319-336_447-616              OS Trypanosoma brucei brucei TREU927
#=GS Q57VP5/319-336_447-616              DE DNA polymerase sigma, putative
#=GS Q57VP5/319-336_447-616              DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; Trypanosoma brucei brucei; 
#=GS Q57VP5/319-336_447-616              DR GO; GO:0003676; GO:0005634; GO:0016779; 
#=GS T1G3V3/3-3_112-268                  AC T1G3V3
#=GS T1G3V3/3-3_112-268                  OS Helobdella robusta
#=GS T1G3V3/3-3_112-268                  DE Uncharacterized protein
#=GS T1G3V3/3-3_112-268                  DR ORG; Eukaryota; Metazoa; Annelida; Clitellata; Hirudinea; Hirudinida; Glossiphoniiformes; Glossiphoniidae; Helobdella; Helobdella robusta; 
#=GS C7G070/445-458_575-733              AC C7G070
#=GS C7G070/445-458_575-733              OS Dictyostelium discoideum
#=GS C7G070/445-458_575-733              DE PAP/25A-associated domain-containing protein
#=GS C7G070/445-458_575-733              DR ORG; Eukaryota; Dictyosteliales; Dictyosteliaceae; Dictyostelium; Dictyostelium discoideum; 
#=GS A4HT94/406-419_530-644_670-711      AC A4HT94
#=GS A4HT94/406-419_530-644_670-711      OS Leishmania infantum
#=GS A4HT94/406-419_530-644_670-711      DE Topoisomerase-related function protein-like protein
#=GS A4HT94/406-419_530-644_670-711      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania infantum; 
#=GS F1A378/304-315_431-590              AC F1A378
#=GS F1A378/304-315_431-590              OS Dictyostelium purpureum
#=GS F1A378/304-315_431-590              DE Uncharacterized protein
#=GS F1A378/304-315_431-590              DR ORG; Eukaryota; Dictyosteliales; Dictyosteliaceae; Dictyostelium; Dictyostelium purpureum; 
#=GS A0A1G4I9S7/319-336_447-616          AC A0A1G4I9S7
#=GS A0A1G4I9S7/319-336_447-616          OS Trypanosoma equiperdum
#=GS A0A1G4I9S7/319-336_447-616          DE NPAPL
#=GS A0A1G4I9S7/319-336_447-616          DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma equiperdum; 
#=GS Q4QIM1/403-416_527-641_667-707      AC Q4QIM1
#=GS Q4QIM1/403-416_527-641_667-707      OS Leishmania major
#=GS Q4QIM1/403-416_527-641_667-707      DE Topoisomerase-related function protein-like protein
#=GS Q4QIM1/403-416_527-641_667-707      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania major species complex; Leishmania major; 
#=GS E9AL83/400-413_524-641_664-704      AC E9AL83
#=GS E9AL83/400-413_524-641_664-704      OS Leishmania mexicana MHOM/GT/2001/U1103
#=GS E9AL83/400-413_524-641_664-704      DE Topoisomerase-related function protein-like protein
#=GS E9AL83/400-413_524-641_664-704      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania mexicana species complex; Leishmania mexicana; 
#=GS A0A3S5H5Z3/405-418_529-643_669-710  AC A0A3S5H5Z3
#=GS A0A3S5H5Z3/405-418_529-643_669-710  OS Leishmania donovani
#=GS A0A3S5H5Z3/405-418_529-643_669-710  DE Topoisomerase-related function protein-like protein
#=GS A0A3S5H5Z3/405-418_529-643_669-710  DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania donovani; 
#=GS E9B969/405-418_529-643_669-710      AC E9B969
#=GS E9B969/405-418_529-643_669-710      OS Leishmania donovani BPK282A1
#=GS E9B969/405-418_529-643_669-710      DE Topoisomerase-related function protein-like protein
#=GS E9B969/405-418_529-643_669-710      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania donovani; 
#=GF SQ 10
Q57VP5/319-336_447-616                      DAAIALHQEICDFVKFHQPRNTLIVIDLLKHYREAEPLIVVVKYFLHQRGMDEPYHGGLGSFALTLMAISFLQQHPIYTG----SPDQRL---------YCGLGRLLVDFFRYYGMYFRYDRCGLSVVGT--------GRCFKRTDVCASSVRPMTNGANSSLGRGGPQSGPPQVLLEDPGCPENNAASSLRNFNVIATSFTHAFRALT--
T1G3V3/3-3_112-268                          -----------------ALNSADQISKFVSTYPSAKPLILLMKHYLAQRDLNEVYSGGVSSYGLMLMIISFLQLHARGDG----LVKD------------ANLGVLLLEFLEHYGCHVNYHKVGIEFLKADNSDDIPQSQYFRRPEQTAY--------------------NTFSLPIMDPCSPENDIMRGSFNLFSVQMAFKHSFKVLTNE
C7G070/445-458_575-733                      ----SFNREIELFSQWLEIENTAVVKGLLKQYKSMRTLLLIIKFFLHQNNLNETYTGGIGSYALALMVVSFIQLRYVPHQYRCQSPTSKIRREYRHAGDATDYGSMLIEFLELYGRSFNYSLYGISLENG--------GYYYKKEEQ--W--------------------GT-SLTLIDPHDRDNDVGKSSFNIPFIRGVLCNSFLKL---
A4HT94/406-419_530-644_670-711              ----ALHQEVTDLVDYLRKRNSECIVQYMNMYPEALPLTLVVKYFVMQRGMHEPYYGGLGSYAATLLVVAFLRQHPIYTT----QPEKRT---------MTGLGRLLVDFFRMCGQHWNYRRVAVCLANY--------AVPSNIDDAMAANVH-------------DPM-GPAQVWIEDPVDASNNAASSLRFFHSLSAMFSYAYLALTT-
F1A378/304-315_431-590                      ------NNKIELFCQWLEIENTQVVKSFLKQYKSMRVLLLVLKFFLQQNHVNETYTGGIGSYALALMVVSYIQLRHVPQNHKL-SPHSKARKEYKHAGDATDYGLMLVEFFELYGLVFNYQLYGISLEHG--------GYYFRKEESKAI--------------------GC-SLTLIDPHDTENDVGKNSFNIVFIRGIFSSSFLKL---
A0A1G4I9S7/319-336_447-616                  DAAIALHQEICDFVKFHQPRNTLIVIDLLKHYREAEPLIVVVKYFLHQRGMDEPYHGGLGSFALTLMAISFLQQHPIYTG----SPDQRL---------YCGLGRLLVDFFRYYGMYFRYDRCGLSVVGT--------GRCFKRTDVCASSVRPMTNGANSSLGRGGPQSGPPQVLLEDPGCPENNAASSLRNFNVIATSFTHAFRALT--
Q4QIM1/403-416_527-641_667-707              ----ALHQEVTDLVDYLRKRNSECIVQYMNMYPEALPLTLVVKYFVMQRGMHEPYYGGLGSYAATLLVVAFLRQHPIYTT----QPEKRT---------MTGLGRLLVDFFRMCGQHWNYRRVAVCLTNY--------AVPSNADDAMAVDVH-------------DPM-GPAQVWIEDPVDASNNAASSLRFFHSLSAMFSYAYLALT--
E9AL83/400-413_524-641_664-704              ----ALHQEVTDLVDYLRKRNSECIVQYMNMYPEALPLTLVVKYFVTQRGMHEPYYGGLGSYAATLLVVAFLRQHPIYTT----QPEKRT---------MTGLGKLLVDFFRTCGQHWNYRRVAVCLANY--------AVPSSSDDAMPADVH----------GEGDPM-GPAQVWIEDPVDASNNAASSLRFFHSLSAMFSYAYLALT--
A0A3S5H5Z3/405-418_529-643_669-710          ----ALHQEVTDLVDYLRKRNSECIVQYMNMYPEALPLTLVVKYFVMQRGMHEPYYGGLGSYAATLLVVAFLRQHPIYTT----QPEKRT---------MTGLGRLLVDFFRMCGQHWNYRRVAVCLANY--------AVPSNIDDAMAANVH-------------DPM-GPAQVWIEDPVDASNNAASSLRFFHSLSAMFSYAYLALTT-
E9B969/405-418_529-643_669-710              ----ALHQEVTDLVDYLRKRNSECIVQYMNMYPEALPLTLVVKYFVMQRGMHEPYYGGLGSYAATLLVVAFLRQHPIYTT----QPEKRT---------MTGLGRLLVDFFRMCGQHWNYRRVAVCLANY--------AVPSNIDDAMAANVH-------------DPM-GPAQVWIEDPVDASNNAASSLRFFHSLSAMFSYAYLALTT-
#=GC scorecons                              0000334455234333443575336335553945636947669686396465959499679775596676866564544400004744530000000002556937967965369344694446546343000000005344434732521220000000000000121075256264993445965556544534544474467449400
#=GC scorecons_70                           ____________________*___*______*_____*_**_****_**___*_*_**_****__**_*_***_*__________*_________________*_******__**___**_________________________*________________________*___*_*_**____**______________*___*__*___
#=GC scorecons_80                           ____________________*__________*_____*_*__*_*__*____*_*_**_****__*____*________________________________*__*__*____*____*__________________________________________________*_______**____*_______________*___*__*___
#=GC scorecons_90                           _______________________________*_____*____*_*__*____*_*_**__*____*____*________________________________*__*__*____*____*__________________________________________________________**____*______________________*___
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