# STOCKHOLM 1.0 #=GF ID 1.10.1380.10/FF/000007 #=GF DE Blast:Membrane metallo-endopeptidase-like 1 #=GF AC 1.10.1380.10/FF/000007 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 18.781 #=GS A0A0B4K692/132-455_508-553 AC A0A0B4K692 #=GS A0A0B4K692/132-455_508-553 OS Drosophila melanogaster #=GS A0A0B4K692/132-455_508-553 DE Neprilysin-2 #=GS A0A0B4K692/132-455_508-553 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila melanogaster; #=GS A0A0B4K692/132-455_508-553 DR GO; GO:0004175; GO:0004222; GO:0005615; GO:0005886; GO:0006508; GO:0008237; GO:0016021; GO:0046692; #=GS A0A0B4K692/132-455_508-553 DR EC; 3.4.24.11; #=GS B4I3S2/132-444_497-542 AC B4I3S2 #=GS B4I3S2/132-444_497-542 OS Drosophila sechellia #=GS B4I3S2/132-444_497-542 DE GM10687 #=GS B4I3S2/132-444_497-542 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila sechellia; #=GS B3M125/134-446_499-544 AC B3M125 #=GS B3M125/134-446_499-544 OS Drosophila ananassae #=GS B3M125/134-446_499-544 DE Uncharacterized protein, isoform A #=GS B3M125/134-446_499-544 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; ananassae subgroup; Drosophila ananassae; #=GS Q295I3/137-449_502-547 AC Q295I3 #=GS Q295I3/137-449_502-547 OS Drosophila pseudoobscura pseudoobscura #=GS Q295I3/137-449_502-547 DE Uncharacterized protein, isoform B #=GS Q295I3/137-449_502-547 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; obscura group; pseudoobscura subgroup; Drosophila pseudoobscura; Drosophila pseudoobscura pseudoobscura; #=GS A0A0P9AU03/134-457_510-555 AC A0A0P9AU03 #=GS A0A0P9AU03/134-457_510-555 OS Drosophila ananassae #=GS A0A0P9AU03/134-457_510-555 DE Uncharacterized protein, isoform B #=GS A0A0P9AU03/134-457_510-555 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; ananassae subgroup; Drosophila ananassae; #=GS A0A3B0KEW2/137-449_502-547 AC A0A3B0KEW2 #=GS A0A3B0KEW2/137-449_502-547 OS Drosophila guanche #=GS A0A3B0KEW2/137-449_502-547 DE Blast:Membrane metallo-endopeptidase-like 1 #=GS A0A3B0KEW2/137-449_502-547 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; obscura group; obscura subgroup; Drosophila guanche; #=GS A0A0R3NP80/137-459_512-557 AC A0A0R3NP80 #=GS A0A0R3NP80/137-459_512-557 OS Drosophila pseudoobscura pseudoobscura #=GS A0A0R3NP80/137-459_512-557 DE Uncharacterized protein, isoform C #=GS A0A0R3NP80/137-459_512-557 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; obscura group; pseudoobscura subgroup; Drosophila pseudoobscura; Drosophila pseudoobscura pseudoobscura; #=GS A0A3B0JT75/137-459_512-557 AC A0A3B0JT75 #=GS A0A3B0JT75/137-459_512-557 OS Drosophila guanche #=GS A0A3B0JT75/137-459_512-557 DE Blast:Membrane metallo-endopeptidase-like 1 #=GS A0A3B0JT75/137-459_512-557 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; obscura group; obscura subgroup; Drosophila guanche; #=GS A0A1W4V1Z2/135-458_511-556 AC A0A1W4V1Z2 #=GS A0A1W4V1Z2/135-458_511-556 OS Drosophila ficusphila #=GS A0A1W4V1Z2/135-458_511-556 DE membrane metallo-endopeptidase-like 1 isoform X1 #=GS A0A1W4V1Z2/135-458_511-556 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; ficusphila subgroup; Drosophila ficusphila; #=GS B4GDU4/137-449_502-547 AC B4GDU4 #=GS B4GDU4/137-449_502-547 OS Drosophila persimilis #=GS B4GDU4/137-449_502-547 DE GL21487 #=GS B4GDU4/137-449_502-547 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; obscura group; pseudoobscura subgroup; Drosophila persimilis; #=GS A0A1W4V2B2/135-447_500-545 AC A0A1W4V2B2 #=GS A0A1W4V2B2/135-447_500-545 OS Drosophila ficusphila #=GS A0A1W4V2B2/135-447_500-545 DE membrane metallo-endopeptidase-like 1 isoform X2 #=GS A0A1W4V2B2/135-447_500-545 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; ficusphila subgroup; Drosophila ficusphila; #=GS B3P240/133-445_498-543 AC B3P240 #=GS B3P240/133-445_498-543 OS Drosophila erecta #=GS B3P240/133-445_498-543 DE GG11422 #=GS B3P240/133-445_498-543 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila erecta; #=GS B4PUG6/133-445_498-543 AC B4PUG6 #=GS B4PUG6/133-445_498-543 OS Drosophila yakuba #=GS B4PUG6/133-445_498-543 DE Uncharacterized protein, isoform A #=GS B4PUG6/133-445_498-543 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila yakuba; #=GS A0A0R1E0B8/133-456_509-554 AC A0A0R1E0B8 #=GS A0A0R1E0B8/133-456_509-554 OS Drosophila yakuba #=GS A0A0R1E0B8/133-456_509-554 DE Uncharacterized protein, isoform B #=GS A0A0R1E0B8/133-456_509-554 DR ORG; Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophilinae; Drosophilini; Drosophila; Sophophora; melanogaster group; melanogaster subgroup; Drosophila yakuba; #=GF SQ 14 A0A0B4K692/132-455_508-553 STFSVISDKLQEQLKDIITAERPETEPKHFRLPNLLYKACMNKTLIETLGPEPITRVAERLGGWPLIKGDSWNADDSWTWQEQVKKFRTAGFSMDYIIDFSIGVDLQNSTKRLIDLDQSSLALSREYLVKGFNETLVTAYYKYMVDIAVLFGANRDLAKTELLLSLEFEMALANISWPNEKRRNSSELYNLRTPAQLQAAYPYVQWVDYMNALLPEGLNVAEDEMINLSVPSFFEDLGKLLAKTPKRVIANYMFWRIHGFSVGFLSEEFRKRQLQYATALSGRQEQEARWKECVDIATSSMDEVCEDDFDSLGISVGSLYVGKHDEMLDNEKLAAYYAKLDIDPDKYFESFLGMNIFGTDYSFNKLRLPV B4I3S2/132-444_497-542 STFSVISDKLQEQLKDIITAERPETEPKHFRLPNLLYKACMNKTLIETLGPEPITRVAERLGGWPLIKGDSWNADDSWTWQEQVKKFRTAGFSMDYIIDFSIGVDLQNSTKRLIDLDQSSLALSREYLVKGFNETLVTAYYEYMVDIAVLFGANRDLAKTELLTSLEFEMALANISWPNEKRRNSSELYNLRTPAQLQAAYPYVQWVDYMNALLPEGLNVAEDEMINLSVPSFFEDLGKLLAKTPKRVIANYMFWRIHGFSVGFLSEEFRKRQLQYATALSGRQEQEARWKECVDIATS-----------SLGISVGSLYVGKHDEMLDNEKLAAYYAKLDIDSDKYFESFLGMNIFGTDYSFNKLRLPV B3M125/134-446_499-544 STFSVISDKLQEQLKDIITAERPETEPKHFRLPNLLYKACMNKTLIETLGPLPITRVAEKLGGWPLLKGDSWNADDTWTWQEQVKKFRTAGFSMDYIIDFSIGVDLQNSTKRLIDLDQSSLALSREYLVKGFNETLVVAYYDYMVDVAVLFGADKELAKKELLSSLEFEIALANISWPNEKRRNSSELYNLRTPMQLQAAYPYVQWVDYMNALLPEGLNVAEDEMINLSVPSFFEDLGKLLAKTPKRVIANYMFWRIHGFSIGFLSEEFRKRQLQYATALSGRQEQEARWKECVDIATG-----------SLGISVGSLYVRKHDEMLDNEKLAQYYAKLDIDPDKYFESFLGMNIFGTDYSFNKLRLPV Q295I3/137-449_502-547 STFSVISDKLQEQLKDIITADRPDTEPKHFRLPNLLYKACMNKTLIESRGAEPITRMAESLGGWPLLKGEAWNADNTWSWQEQVKKFRNAGFSMDYIIDFSIGVDLQNSTKRLIDLDQSALALSREYLVKGFNETLVTAYYEYMVDIAVLFGAKKDQAKKELLQSLEFEMALANISWPNEKRRNSSELYNLRSPQQLQAAYPYVQWVDYMNALLPEGLSMADDEMINLSVPSFFEDLGKLLAKTPQRDIANYMFWRIHSFSIGFLSEEFRKRQLQYATALSGRQEQEARWKECVDIATG-----------SLGISVGSLYVRKHDEMLDNEKLAKYYAKLDIDPDKYFESFLGMNIFGTDYSFNKLRLPV A0A0P9AU03/134-457_510-555 STFSVISDKLQEQLKDIITAERPETEPKHFRLPNLLYKACMNKTLIETLGPLPITRVAEKLGGWPLLKGDSWNADDTWTWQEQVKKFRTAGFSMDYIIDFSIGVDLQNSTKRLIDLDQSSLALSREYLVKGFNETLVVAYYDYMVDVAVLFGADKELAKKELLSSLEFEIALANISWPNEKRRNSSELYNLRTPMQLQAAYPYVQWVDYMNALLPEGLNVAEDEMINLSVPSFFEDLGKLLAKTPKRVIANYMFWRIHGFSIGFLSEEFRKRQLQYATALSGRQEQEARWKECVDIATGSMDEESEDDYDSLGISVGSLYVRKHDEMLDNEKLAQYYAKLDIDPDKYFESFLGMNIFGTDYSFNKLRLPV A0A3B0KEW2/137-449_502-547 STFSVISDKLQEQLKDIITADRPDTEPKHFRLPNLLYKACMNKTLIESRGAEPITRMAESLGGWPLLKGDAWNADNTWSWQEQVKKFRNAGFSMDYIIDFSIGVDLQNSTKRLIDLDQSALALSREYLVKGFNETLVTAYYDYMVDIAVLFGANKEQAKKELLQSLEFEMALANISWPNEKRRNSSELYNLRSPQQLQAAYPYVQWVDYMNALLPEGLSMADDEMINLSVPSFFEDLGKLLAKTPQRDIANYMFWRIHSFSIGFLSEEFRKRQLQYATALSGRQEQEARWKECVDIATG-----------SLGISVGSLYVRKHDEMLDNEKLAKYYAKLDINPDKYFESFLGMNIFGTDYSFNKLRLPV A0A0R3NP80/137-459_512-557 STFSVISDKLQEQLKDIITADRPDTEPKHFRLPNLLYKACMNKTLIESRGAEPITRMAESLGGWPLLKGEAWNADNTWSWQEQVKKFRNAGFSMDYIIDFSIGVDLQNSTKRLIDLDQSALALSREYLVKGFNETLVTAYYEYMVDIAVLFGAKKDQAKKELLQSLEFEMALANISWPNEKRRNSSELYNLRSPQQLQAAYPYVQWVDYMNALLPEGLSMADDEMINLSVPSFFEDLGKLLAKTPQRDIANYMFWRIHSFSIGFLSEEFRKRQLQYATALSGRQEQEARWKECVDIATGSMDEE-EEDNDSLGISVGSLYVRKHDEMLDNEKLAKYYAKLDIDPDKYFESFLGMNIFGTDYSFNKLRLPV A0A3B0JT75/137-459_512-557 STFSVISDKLQEQLKDIITADRPDTEPKHFRLPNLLYKACMNKTLIESRGAEPITRMAESLGGWPLLKGDAWNADNTWSWQEQVKKFRNAGFSMDYIIDFSIGVDLQNSTKRLIDLDQSALALSREYLVKGFNETLVTAYYDYMVDIAVLFGANKEQAKKELLQSLEFEMALANISWPNEKRRNSSELYNLRSPQQLQAAYPYVQWVDYMNALLPEGLSMADDEMINLSVPSFFEDLGKLLAKTPQRDIANYMFWRIHSFSIGFLSEEFRKRQLQYATALSGRQEQEARWKECVDIATGSMDEE-EEDNDSLGISVGSLYVRKHDEMLDNEKLAKYYAKLDINPDKYFESFLGMNIFGTDYSFNKLRLPV A0A1W4V1Z2/135-458_511-556 STFSVISDKLQEQLKDIITAERPESEPKHFRLPNLLYKACMNKTLIESLGAEPITRVAEKLGGWPLIKGEGWNADDSWTWQEQVKKFRKAGFSMDYIIDFSIGVDLQNSTKRLIDLDQSALALSREYLVKGFNETLVKAYYDYMVDIAVLFGANRELAKTELLSSLEFEMALANISWPNEKRRNSSELYNLRTPAQLQAAYPYVQWVDYMNALLPEGLVVAADEMINLSVPSFFEDLGKLLAKTPKRVIANYMFWRIHGFSVGFLSEEFRKRQLQYATALSGRQEQEARWKECVDIATGSMDEESEEDFDSLGISVGSLYVRKHDEMLDNEKLAKYYAKLDIDPDQYFQSFLGMNIFGTNYSFNKLRLPV B4GDU4/137-449_502-547 STFSVISDKLQEQLKDIITADRPDTEPKHFRLPNLLYKACMNKTLIESRGAEPITRMAESLGGWPLLKGEAWNADNTWSWQEQVKKFRNAGFSMDYIIDFSIGVDLQNSTKRLIDLDQSALALSREYLVKGFNETLVTAYYEYMVDIAVLFGAKKDQAKKELLQSLEFEMALANISWPNEKRRNSSELYNLRSPQQLQAAYPYVQWVDYMNALLPEGLSMADDEMINLSVPSFFEDLGKLLAKTPQRDIANYMFWRIHSFSIGFLSEEFRKRQLQYATALSGRQEQEARWKECVDIATD-----------SLGISVGSLYVRKHDEMLDNEKLAKYYAKLDIDPDKYFESFLGMNIFGTDYSFNKLRLPV A0A1W4V2B2/135-447_500-545 STFSVISDKLQEQLKDIITAERPESEPKHFRLPNLLYKACMNKTLIESLGAEPITRVAEKLGGWPLIKGEGWNADDSWTWQEQVKKFRKAGFSMDYIIDFSIGVDLQNSTKRLIDLDQSALALSREYLVKGFNETLVKAYYDYMVDIAVLFGANRELAKTELLSSLEFEMALANISWPNEKRRNSSELYNLRTPAQLQAAYPYVQWVDYMNALLPEGLVVAADEMINLSVPSFFEDLGKLLAKTPKRVIANYMFWRIHGFSVGFLSEEFRKRQLQYATALSGRQEQEARWKECVDIATG-----------SLGISVGSLYVRKHDEMLDNEKLAKYYAKLDIDPDQYFQSFLGMNIFGTNYSFNKLRLPV B3P240/133-445_498-543 STFSVISDKLQEQLKDIITAERPETEPKHFRLPNLLYRACMNKTLIEALGPEPITRMAEKLGGWPLIKGDSWNADDSWTWQEQVKKFRTAGFSMDYIIDFSIGVDLQNSTKRLIDLDQSSLALSREYLVKGFNETLVTAYYEYMVDIAVLFGANRDLAKTELLSSLEFEIALANISWPNEKRRNSSELYNLRTTAQLQAAYPYVQWVDYMNALLPEGLNLVEDEMINLSVPSFFADLGKLLAKTPKRVIANYMFWRIHGFSVGFLSEEFRKRQLQYATALSGRQEQEARWKECVDIATS-----------SLGISVGSLYVGKHDEMLDNEKLAAYYAKLDIDPDKYFESFLGMNIFGTDYSFNKLRLPV B4PUG6/133-445_498-543 STFSVISDKLQEQLKDIITAERPKTEPKHFRLPNLLYRACMNKTLIETLGPEPIARMAEKLGGWPLIKGESWNADDSWTWQEQVKKFRTAGFSMDYIIDFSIGVDLQNSTKRLIDLDQSSLALSREYLVKGFNETLVTAYYEYMVDIAVLFGANRDLAKTELLSSLEFEIALANISWPNEKRRNSSELYNLRTTAQLQAAYPYVQWVDYMNALLPEGLNVAEDEMINLSVPSFFEELGKLLGRTPKRVIANYMFWRIHGFSVGFLSEEFRKRQLEYATALSGRQEQEARWKECVDIATS-----------SLGISVGSLYVGKHDEMLDNEKLAAYYAKLDIDPDKYFESFLGMNIFGTDYSFNKLRLPV A0A0R1E0B8/133-456_509-554 STFSVISDKLQEQLKDIITAERPKTEPKHFRLPNLLYRACMNKTLIETLGPEPIARMAEKLGGWPLIKGESWNADDSWTWQEQVKKFRTAGFSMDYIIDFSIGVDLQNSTKRLIDLDQSSLALSREYLVKGFNETLVTAYYEYMVDIAVLFGANRDLAKTELLSSLEFEIALANISWPNEKRRNSSELYNLRTTAQLQAAYPYVQWVDYMNALLPEGLNVAEDEMINLSVPSFFEELGKLLGRTPKRVIANYMFWRIHGFSVGFLSEEFRKRQLEYATALSGRQEQEARWKECVDIATSSMDEICEEDFYSLGISVGSLYVGKHDEMLDNEKLAAYYAKLDIDPDKYFESFLGMNIFGTDYSFNKLRLPV #=GC scorecons 9999999999999999999979967999999999999799999999955966997969959999996997599996696999999999599999999999999999999999999999969999999999999999959996999989999996775995999499999699999999999999999999996749999999999999999999999956859999999999998899999789969599999999996997999999999999799999999999999999999999511110011101999999999996999999999999599999997897997999999999979999999999 #=GC scorecons_70 ***********************_***********************__*_********_**********_*****_***********_******************************_*****************_***************_**_**_***_******************************_***********************__*_*************************_**************************************************____________***********_************_*********************************** #=GC scorecons_80 ***********************_***********************__*__****_**_******_**__****__*_*********_******************************_*****************_***_***********____**_***_*****_**********************___***********************__*_***********************_*_**********_**_************************************____________***********_************_*********************************** #=GC scorecons_90 ********************_**__************_*********__*__**_*_**_******_**__****__*_*********_******************************_*****************_***_****_******____**_***_*****_**********************___***********************__*_*************_*****__**_*_**********_**_************_***********************____________***********_************_*******_**_**_**********_********** //