# STOCKHOLM 1.0
#=GF ID 1.10.132.10/FF/000006
#=GF DE DNA topoisomerase type IB small subunit
#=GF AC 1.10.132.10/FF/000006
#=GF TP FunFam
#=GF DR CATH: v4.3
#=GF DR DOPS: 71.958
#=GS Q7Z011/135-273      AC Q7Z011
#=GS Q7Z011/135-273      OS Trypanosoma brucei
#=GS Q7Z011/135-273      DE Type IB DNA topoisomerase small subunit
#=GS Q7Z011/135-273      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; 
#=GS Q7Z011/135-273      DR GO; GO:0003917; GO:0005634; GO:0006265; GO:0006333; 
#=GS A0A229XBA8/740-889  AC A0A229XBA8
#=GS A0A229XBA8/740-889  OS Aspergillus turcosus
#=GS A0A229XBA8/740-889  DE DNA topoisomerase I
#=GS A0A229XBA8/740-889  DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus; Aspergillus turcosus; 
#=GS Q95Z89/150-262      AC Q95Z89
#=GS Q95Z89/150-262      OS Leishmania major
#=GS Q95Z89/150-262      DE DNA topoisomerase type IB small subunit
#=GS Q95Z89/150-262      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania major species complex; Leishmania major; 
#=GS Q95Z89/150-262      DR GO; GO:0003917; GO:0005634; GO:0006265; GO:0006333; 
#=GS A0A1G4I033/135-273  AC A0A1G4I033
#=GS A0A1G4I033/135-273  OS Trypanosoma equiperdum
#=GS A0A1G4I033/135-273  DE DNA topoisomerase type IB small subunit
#=GS A0A1G4I033/135-273  DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma equiperdum; 
#=GS Q38EP5/135-273      AC Q38EP5
#=GS Q38EP5/135-273      OS Trypanosoma brucei brucei TREU927
#=GS Q38EP5/135-273      DE DNA topoisomerase type IB small subunit
#=GS Q38EP5/135-273      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; Trypanosoma brucei brucei; 
#=GS Q38EP5/135-273      DR GO; GO:0003917; GO:0005634; GO:0006265; GO:0006333; 
#=GS C9ZXZ7/135-273      AC C9ZXZ7
#=GS C9ZXZ7/135-273      OS Trypanosoma brucei gambiense DAL972
#=GS C9ZXZ7/135-273      DE DNA topoisomerase type IB small subunit,putative
#=GS C9ZXZ7/135-273      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; Trypanosoma brucei gambiense; 
#=GS A0A3L6L1Z8/135-273  AC A0A3L6L1Z8
#=GS A0A3L6L1Z8/135-273  OS Trypanosoma brucei equiperdum
#=GS A0A3L6L1Z8/135-273  DE DNA topoisomerase type IB small subunit
#=GS A0A3L6L1Z8/135-273  DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; Trypanosoma brucei equiperdum; 
#=GS A4HS02/150-262      AC A4HS02
#=GS A4HS02/150-262      OS Leishmania infantum
#=GS A4HS02/150-262      DE DNA topoisomerase type IB small subunit
#=GS A4HS02/150-262      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania infantum; 
#=GS Q8WQM6/150-262      AC Q8WQM6
#=GS Q8WQM6/150-262      OS Leishmania donovani
#=GS Q8WQM6/150-262      DE DNA topoisomerase I-like protein
#=GS Q8WQM6/150-262      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania donovani; 
#=GS A0A2I1BW44/721-873  AC A0A2I1BW44
#=GS A0A2I1BW44/721-873  OS Aspergillus novofumigatus IBT 16806
#=GS A0A2I1BW44/721-873  DE DNA topoisomerase I
#=GS A0A2I1BW44/721-873  DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus; Aspergillus novofumigatus; 
#=GS A1D4R5/738-886      AC A1D4R5
#=GS A1D4R5/738-886      OS Aspergillus fischeri NRRL 181
#=GS A1D4R5/738-886      DE DNA topoisomerase I
#=GS A1D4R5/738-886      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus; Aspergillus fischeri; 
#=GS A0A0K8LPD9/735-886  AC A0A0K8LPD9
#=GS A0A0K8LPD9/735-886  OS Aspergillus udagawae
#=GS A0A0K8LPD9/735-886  DE DNA topoisomerase I
#=GS A0A0K8LPD9/735-886  DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus; Aspergillus udagawae; 
#=GS B0XN02/849-998      AC B0XN02
#=GS B0XN02/849-998      OS Aspergillus fumigatus A1163
#=GS B0XN02/849-998      DE DNA topoisomerase I
#=GS B0XN02/849-998      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus; Aspergillus fumigatus; 
#=GS A0A0S7E1A6/743-892  AC A0A0S7E1A6
#=GS A0A0S7E1A6/743-892  OS Aspergillus lentulus
#=GS A0A0S7E1A6/743-892  DE DNA topoisomerase I
#=GS A0A0S7E1A6/743-892  DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus; Aspergillus lentulus; 
#=GS E9B7X3/150-262      AC E9B7X3
#=GS E9B7X3/150-262      OS Leishmania donovani BPK282A1
#=GS E9B7X3/150-262      DE DNA topoisomerase type IB small subunit
#=GS E9B7X3/150-262      DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania donovani; 
#=GS Q4WK70/849-998      AC Q4WK70
#=GS Q4WK70/849-998      OS Aspergillus fumigatus Af293
#=GS Q4WK70/849-998      DE DNA topoisomerase I
#=GS Q4WK70/849-998      DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus; Aspergillus fumigatus; 
#=GS A0A0J5PQ48/715-867  AC A0A0J5PQ48
#=GS A0A0J5PQ48/715-867  OS Aspergillus fumigatus Z5
#=GS A0A0J5PQ48/715-867  DE DNA topoisomerase I
#=GS A0A0J5PQ48/715-867  DR ORG; Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus; Aspergillus fumigatus; 
#=GF SQ 17
Q7Z011/135-273              --------------------SDDEESV---SEDNLTFFELAERSGLMNDIKNKVNSGEGEQEEEEEVHIDGKPPRPKFLRSFPRDIEAEIGKHEKRLKDVENMLKMKQDNKTVSLGTSKVNYIDPRIVCSWANENNVPISRLFSATLQKKFPWALKA--RDFTF
A0A229XBA8/740-889          ---HQAFLIEEQRQKIKKKFEKENEKLAAEGEKEMKASELESRLEVVKEMESKFK----KENKTGKVEVEGKSPSVE-------KLEAAIKKLEERIETMELQAQDKEENKEVALGTSKINYIDPRLTVVFSKKFNVPIEKFFSKSLREKFEWAIKSVDENWEF
Q95Z89/150-262              ----------------------------------------AQSQGLVNK--------EILTQEEEEVPT-LVPPRPPVVRSFPNDIGKALERYRERLNREENIIRIKDDNKAVSLGTSKINYIDPRIICSWAKAQDVPINKIFSATIQKKFPWAMNA--ENFDF
A0A1G4I033/135-273          --------------------SDDEESV---SEDNLTFFELAERSGLMNDIKNKVNSGEGEQEEEEEVHIDGKPPRPKFLRSFPRDIEAEIGKHEKRLKDVENMLKMKQDNKTVSLGTSKVNYIDPRIVCSWANENNVPISRLFSATLQKKFPWALKA--RDFTF
Q38EP5/135-273              --------------------SDDEESV---SEDNLTFFELAERSGLMNDIKNKVNSGEGEQEEEEEVHIDGKPPRPKFLRSFPRDIEAEIGKHEKRLKDVENMLKMKQDNKTVSLGTSKVNYIDPRIVCSWANENNVPISRLFSATLQKKFPWALKA--RDFTF
C9ZXZ7/135-273              --------------------SDDEESV---SEDNLTFFELAERSGLMNDIKNKVNSGEGEQEEEEEVHIDGKPPRPKFLRSFPRDIEAEIGKHEKRLKDVENMLKMKQDNKTVSLGTSKVNYIDPRIVCSWANENNVPISRLFSATLQKKFPWALKA--RDFTF
A0A3L6L1Z8/135-273          --------------------SDDEESV---SEDNLTFFELAERSGLMNDIKNKVNSGEGEQEEEEEVHIDGKPPRPKFLRSFPRDIEAEIGKHEKRLKDVENMLKMKQDNKTVSLGTSKVNYIDPRIVCSWANENNVPISRLFSATLQKKFPWALKA--RDFTF
A4HS02/150-262              ----------------------------------------AQSQGLVNK--------EVLAQEEEEVPT-LVPPRPPVVRSFPNDIGKALERYRERLNREENIIRIKDDNKAVSLGTSKINYIDPRIICSWAKAQDVPINKIFSATIQKKFPWAMNA--ENFDF
Q8WQM6/150-262              ----------------------------------------AQSQGLVNK--------EVLTQEEEEVPT-LVPPRPPVVRSFPNDIGKALERYRERLNREENIIRIKDDNKAVSLGTSKINYIDPRIICSWAKAQDVPINKIFSATIQKKFPWAMNA--ENFDF
A0A2I1BW44/721-873          VKEHQAYLLEEQRQKIKKKFEKENEKLAADGEKEMKASELESRLEPVKEMENKFK----KENKTGKVEVEGKGPSVE-------KLEAAITKLEQRIETMELQAQDKEENKEVALGTSKINYIDPRLTVVFSKKFNVPIEKFFSKSLREKFEWAIKSVDENWEF
A1D4R5/738-886              ----QAYLLEEQRQKIKKKFEKENEKLAAEGEKEMKASELESRLEAVKEMENKFK----KENKTGKVDVEGKSSSVE-------KLEAAITKLEQRIETMELQAQDKEENKEVALGTSKINYIDPRLTVVFSKKFNVPIEKFFSKSLREKFEWAIKSVDENWEF
A0A0K8LPD9/735-886          -KEHQAYLVEEQRQKIKKKFEKENEKLAAEGEKEMKASELESRLEAVKEMENKFK----KENKTGKVEVEGKGPSVE-------KLEAAITKLEQRIETMELQAQDKEENKEVALGTSKINYIDPRLTVVFSKKFNVPIEKFFSKSLREKFEWAIKSVDENWEF
B0XN02/849-998              ---HQAFLLEEQRQKIKKKFEKENEKLAAEGEKEMKASELEHRLEAVKEMENKFM----RENKTGKVEVEGKSPSVE-------KLEAAITKLEQRIETMELQAQDKEDNKEVALGTSKINYIDPRLTVVFSKKFNVPIEKFFSKSLREKFEWAIKSVDENWEF
A0A0S7E1A6/743-892          ---HQAYLLEEQRQKIKKKFEKDNEKLAAEGEKEMKASELESRLEAVKEMENKFR----KENKTGKVEVEGKGPSVE-------KLEAAITKLEQRIETMELQAQDKEENKEVALGTSKINYIDPRLTVVFSKKFNVPIEKFFSKSLREKFEWAIKSVDENWEF
E9B7X3/150-262              ----------------------------------------AQSQGLVNK--------EVLTQEEEEVPT-LVPPRPPVVRSFPNDIGKALERYRERLNREESIIRIKDDNKAVSLGTSKINYIDPRIICSWAKAQDVPINKIFSATIQKKFPWAMNA--ENFDF
Q4WK70/849-998              ---HQAFLLEEQRQKIKKKFEKENEKLAAEGEKEMKASELEHRLEAVKEMENKFM----RENKTGKVEVEGKSPSVE-------KLEAAITKLEQRIETMELQAQDKEDNKEVALGTSKINYIDPRLTVVFSKKFNVPIEKFFSKSLREKFEWAIKSVDENWEF
A0A0J5PQ48/715-867          VKEHQAFLLEEQRQKIKKKFEKENEKLAAEGEKEMKASELEHRLEAVKEMENKFM----RENKTGKVEVEGKSPSVE-------KLEAAITKLEQRIETMELQAQDKEDNKEVALGTSKINYIDPRLTVVFSKKFNVPIEKFFSKSLREKFEWAIKSVDENWEF
#=GC scorecons              00011111111111111111223342311134233222445464656653344220021345656694535558554112222156666647465965449444549579949699999799999965555664369994759956666995995661166559
#=GC scorecons_70           ______________________________________________*___________________*______*___________**__*_*_*_**___*_____*_***_*_*************_____*__****_*_**__**_**_**_*___**__*
#=GC scorecons_80           __________________________________________________________________*______*_________________*___*____*_____*_***_*_************__________***_*_**_____**_**_________*
#=GC scorecons_90           __________________________________________________________________*______*_____________________*____*_____*__**_*_*****_******__________***___**_____**_**_________*
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