# STOCKHOLM 1.0 #=GF ID 1.10.1300.10/FF/000025 #=GF DE Phosphodiesterase #=GF AC 1.10.1300.10/FF/000025 #=GF TP FunFam #=GF DR CATH: v4.3 #=GF DR DOPS: 82.974 #=GS 5l9hB00/27-360 AC Q8WQX9 #=GS 5l9hB00/27-360 OS Trypanosoma brucei #=GS 5l9hB00/27-360 DE Phosphodiesterase #=GS 5l9hB00/27-360 DR CATH; 5l9h; B:585-918; #=GS 5l9hB00/27-360 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; #=GS 5l9hB00/27-360 DR GO; GO:0000902; GO:0004114; GO:0004115; GO:0005737; GO:0005930; #=GS Q9GQU6/574-924 AC Q9GQU6 #=GS Q9GQU6/574-924 OS Trypanosoma brucei #=GS Q9GQU6/574-924 DE Phosphodiesterase #=GS Q9GQU6/574-924 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; #=GS Q9GQU6/574-924 DR GO; GO:0004114; GO:0005737; GO:0005930; #=GS Q4QF31/582-940 AC Q4QF31 #=GS Q4QF31/582-940 OS Leishmania major #=GS Q4QF31/582-940 DE Phosphodiesterase #=GS Q4QF31/582-940 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania major species complex; Leishmania major; #=GS Q4QF31/582-940 DR GO; GO:0005737; GO:0005930; #=GS A7SW30/291-600 AC A7SW30 #=GS A7SW30/291-600 OS Nematostella vectensis #=GS A7SW30/291-600 DE Phosphodiesterase #=GS A7SW30/291-600 DR ORG; Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria; Edwardsiidae; Nematostella; Nematostella vectensis; #=GS 5l9hA00/28-360 AC Q8WQX9 #=GS 5l9hA00/28-360 OS Trypanosoma brucei #=GS 5l9hA00/28-360 DE Phosphodiesterase #=GS 5l9hA00/28-360 DR CATH; 5l9h; A:586-918; #=GS 5l9hA00/28-360 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; #=GS 5l9hA00/28-360 DR GO; GO:0000902; GO:0004114; GO:0004115; GO:0005737; GO:0005930; #=GS 5l8yB00/28-360 AC Q8WQX9 #=GS 5l8yB00/28-360 OS Trypanosoma brucei #=GS 5l8yB00/28-360 DE Phosphodiesterase #=GS 5l8yB00/28-360 DR CATH; 5l8y; B:586-917; #=GS 5l8yB00/28-360 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; #=GS 5l8yB00/28-360 DR GO; GO:0000902; GO:0004114; GO:0004115; GO:0005737; GO:0005930; #=GS 5l8yA00/28-360 AC Q8WQX9 #=GS 5l8yA00/28-360 OS Trypanosoma brucei #=GS 5l8yA00/28-360 DE Phosphodiesterase #=GS 5l8yA00/28-360 DR CATH; 5l8y; A:586-918; #=GS 5l8yA00/28-360 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; #=GS 5l8yA00/28-360 DR GO; GO:0000902; GO:0004114; GO:0004115; GO:0005737; GO:0005930; #=GS 5l8cB00/28-360 AC Q8WQX9 #=GS 5l8cB00/28-360 OS Trypanosoma brucei #=GS 5l8cB00/28-360 DE Phosphodiesterase #=GS 5l8cB00/28-360 DR CATH; 5l8c; B:586-917; #=GS 5l8cB00/28-360 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; #=GS 5l8cB00/28-360 DR GO; GO:0000902; GO:0004114; GO:0004115; GO:0005737; GO:0005930; #=GS 5l8cA00/28-360 AC Q8WQX9 #=GS 5l8cA00/28-360 OS Trypanosoma brucei #=GS 5l8cA00/28-360 DE Phosphodiesterase #=GS 5l8cA00/28-360 DR CATH; 5l8c; A:586-918; #=GS 5l8cA00/28-360 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; #=GS 5l8cA00/28-360 DR GO; GO:0000902; GO:0004114; GO:0004115; GO:0005737; GO:0005930; #=GS 5g5vB00/29-360 AC Q8WQX9 #=GS 5g5vB00/29-360 OS Trypanosoma brucei #=GS 5g5vB00/29-360 DE Phosphodiesterase #=GS 5g5vB00/29-360 DR CATH; 5g5v; B:587-918; #=GS 5g5vB00/29-360 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; #=GS 5g5vB00/29-360 DR GO; GO:0000902; GO:0004114; GO:0004115; GO:0005737; GO:0005930; #=GS 5g5vA00/25-360 AC Q8WQX9 #=GS 5g5vA00/25-360 OS Trypanosoma brucei #=GS 5g5vA00/25-360 DE Phosphodiesterase #=GS 5g5vA00/25-360 DR CATH; 5g5v; A:583-917; #=GS 5g5vA00/25-360 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; #=GS 5g5vA00/25-360 DR GO; GO:0000902; GO:0004114; GO:0004115; GO:0005737; GO:0005930; #=GS 5g57B00/28-360 AC Q8WQX9 #=GS 5g57B00/28-360 OS Trypanosoma brucei #=GS 5g57B00/28-360 DE Phosphodiesterase #=GS 5g57B00/28-360 DR CATH; 5g57; B:586-917; #=GS 5g57B00/28-360 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; #=GS 5g57B00/28-360 DR GO; GO:0000902; GO:0004114; GO:0004115; GO:0005737; GO:0005930; #=GS 5g57A00/28-360 AC Q8WQX9 #=GS 5g57A00/28-360 OS Trypanosoma brucei #=GS 5g57A00/28-360 DE Phosphodiesterase #=GS 5g57A00/28-360 DR CATH; 5g57; A:586-918; #=GS 5g57A00/28-360 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; #=GS 5g57A00/28-360 DR GO; GO:0000902; GO:0004114; GO:0004115; GO:0005737; GO:0005930; #=GS 5g2bB00/28-360 AC Q8WQX9 #=GS 5g2bB00/28-360 OS Trypanosoma brucei #=GS 5g2bB00/28-360 DE Phosphodiesterase #=GS 5g2bB00/28-360 DR CATH; 5g2b; B:586-917; #=GS 5g2bB00/28-360 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; #=GS 5g2bB00/28-360 DR GO; GO:0000902; GO:0004114; GO:0004115; GO:0005737; GO:0005930; #=GS 5g2bA00/28-360 AC Q8WQX9 #=GS 5g2bA00/28-360 OS Trypanosoma brucei #=GS 5g2bA00/28-360 DE Phosphodiesterase #=GS 5g2bA00/28-360 DR CATH; 5g2b; A:586-918; #=GS 5g2bA00/28-360 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; #=GS 5g2bA00/28-360 DR GO; GO:0000902; GO:0004114; GO:0004115; GO:0005737; GO:0005930; #=GS 4phlB00/1-347 AC Q8WQX9 #=GS 4phlB00/1-347 OS Trypanosoma brucei #=GS 4phlB00/1-347 DE Phosphodiesterase #=GS 4phlB00/1-347 DR CATH; 4phl; B:587-918; #=GS 4phlB00/1-347 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; #=GS 4phlB00/1-347 DR GO; GO:0000902; GO:0004114; GO:0004115; GO:0005737; GO:0005930; #=GS 4phlA00/1-347 AC Q8WQX9 #=GS 4phlA00/1-347 OS Trypanosoma brucei #=GS 4phlA00/1-347 DE Phosphodiesterase #=GS 4phlA00/1-347 DR CATH; 4phl; A:587-916; #=GS 4phlA00/1-347 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; #=GS 4phlA00/1-347 DR GO; GO:0000902; GO:0004114; GO:0004115; GO:0005737; GO:0005930; #=GS 4i15B00/1-343 AC Q8WQX9 #=GS 4i15B00/1-343 OS Trypanosoma brucei #=GS 4i15B00/1-343 DE Phosphodiesterase #=GS 4i15B00/1-343 DR CATH; 4i15; B:586-918; #=GS 4i15B00/1-343 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; #=GS 4i15B00/1-343 DR GO; GO:0000902; GO:0004114; GO:0004115; GO:0005737; GO:0005930; #=GS 4i15A00/1-343 AC Q8WQX9 #=GS 4i15A00/1-343 OS Trypanosoma brucei #=GS 4i15A00/1-343 DE Phosphodiesterase #=GS 4i15A00/1-343 DR CATH; 4i15; A:586-918; #=GS 4i15A00/1-343 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; #=GS 4i15A00/1-343 DR GO; GO:0000902; GO:0004114; GO:0004115; GO:0005737; GO:0005930; #=GS 2r8qB00/1-359 AC Q6S996 #=GS 2r8qB00/1-359 OS Leishmania major #=GS 2r8qB00/1-359 DE Phosphodiesterase #=GS 2r8qB00/1-359 DR CATH; 2r8q; B:597-931; #=GS 2r8qB00/1-359 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania major species complex; Leishmania major; #=GS 2r8qA00/1-359 AC Q6S996 #=GS 2r8qA00/1-359 OS Leishmania major #=GS 2r8qA00/1-359 DE Phosphodiesterase #=GS 2r8qA00/1-359 DR CATH; 2r8q; A:597-931; #=GS 2r8qA00/1-359 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania major species complex; Leishmania major; #=GS F7BQ75/410-744 AC F7BQ75 #=GS F7BQ75/410-744 OS Ciona intestinalis #=GS F7BQ75/410-744 DE Phosphodiesterase #=GS F7BQ75/410-744 DR ORG; Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Enterogona; Phlebobranchia; Cionidae; Ciona; Ciona intestinalis; #=GS Q38F46/574-924 AC Q38F46 #=GS Q38F46/574-924 OS Trypanosoma brucei brucei TREU927 #=GS Q38F46/574-924 DE Phosphodiesterase #=GS Q38F46/574-924 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; Trypanosoma brucei brucei; #=GS Q38F46/574-924 DR GO; GO:0000902; GO:0004114; GO:0004115; GO:0005737; GO:0005930; #=GS A4HWN7/582-940 AC A4HWN7 #=GS A4HWN7/582-940 OS Leishmania infantum #=GS A4HWN7/582-940 DE Phosphodiesterase #=GS A4HWN7/582-940 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania infantum; #=GS E9AQE5/582-940 AC E9AQE5 #=GS E9AQE5/582-940 OS Leishmania mexicana MHOM/GT/2001/U1103 #=GS E9AQE5/582-940 DE Phosphodiesterase #=GS E9AQE5/582-940 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania mexicana species complex; Leishmania mexicana; #=GS E9BCJ3/582-940 AC E9BCJ3 #=GS E9BCJ3/582-940 OS Leishmania donovani BPK282A1 #=GS E9BCJ3/582-940 DE Phosphodiesterase #=GS E9BCJ3/582-940 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania donovani; #=GS Q8WQX9/574-924 AC Q8WQX9 #=GS Q8WQX9/574-924 OS Trypanosoma brucei #=GS Q8WQX9/574-924 DE Phosphodiesterase #=GS Q8WQX9/574-924 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; #=GS Q8WQX9/574-924 DR GO; GO:0000902; GO:0004114; GO:0004115; GO:0005737; GO:0005930; #=GS Q38F42/574-923 AC Q38F42 #=GS Q38F42/574-923 OS Trypanosoma brucei brucei TREU927 #=GS Q38F42/574-923 DE Phosphodiesterase #=GS Q38F42/574-923 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Trypanosoma; Trypanozoon; Trypanosoma brucei; Trypanosoma brucei brucei; #=GS Q38F42/574-923 DR GO; GO:0004114; GO:0005737; GO:0005930; #=GS A4HWN6/572-930 AC A4HWN6 #=GS A4HWN6/572-930 OS Leishmania infantum #=GS A4HWN6/572-930 DE Phosphodiesterase #=GS A4HWN6/572-930 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania donovani species complex; Leishmania infantum; #=GS Q6S996/582-940 AC Q6S996 #=GS Q6S996/582-940 OS Leishmania major #=GS Q6S996/582-940 DE Phosphodiesterase #=GS Q6S996/582-940 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania major species complex; Leishmania major; #=GS E9AQE4/572-930 AC E9AQE4 #=GS E9AQE4/572-930 OS Leishmania mexicana MHOM/GT/2001/U1103 #=GS E9AQE4/572-930 DE Phosphodiesterase #=GS E9AQE4/572-930 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania mexicana species complex; Leishmania mexicana; #=GS Q6S997/572-930 AC Q6S997 #=GS Q6S997/572-930 OS Leishmania major #=GS Q6S997/572-930 DE Phosphodiesterase #=GS Q6S997/572-930 DR ORG; Eukaryota; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania; Leishmania major species complex; Leishmania major; #=GF SQ 32 5l9hB00/27-360 ----------------------------RVTAITKVEREAVLVCEL-PSFDVTDVEFDLFRARESTDKPLDVAAAIAYRLLLGSGLPQKFGCSDEVLLNFILQCRKKYRNVPYHNFYHVVDVCQTIHTFLYRGNVYEKLTELECFVLLITALVHDLDHMGLNNSFYLKTESPLGILSSASGNTSVLEVHHCNLAVEILSDPESDVFDGLEGAERTLAFRSMIDCVLATDMAKHGSALEAFLA--SAADQSSDEAAFHRMTMEIILKAGDISNVTKPFDISRQWAMAVTEEFYRQGDMEKERGVEV-LPMFDRSKNMELAKGQIGFIDFVAAPFFQKIVDACLQGMQWTVDRIKSNRAQWERVLETR--------- Q9GQU6/574-924 ---------------FNKNVPSRAVK--RVTAITKVEREAVLVCEL-PSFDVTDVEFDLFRARESTDKPLDVAAAIAYRLLLGSGLPQKFGCSDEVLLNFILQCRKKYRNVPYHNFYHVVDVCQTIYTFLYRGNVYEKLTELECFVLLITALVHDLDHMGLNNSFYLKTESPLGILSSASGNTSVLEVHHCNLAVEILSDPESDVFGGLEGAERTLAFRSMIDCVLATDMAKHGSALEAFLA--SAADQSSDEAAFHRMTMEIILKAGDISNVTKPFDISRQWAMAVTEEFYRQGDMEKERGVEV-LPMFDRSKNMELAKGQIGFIDFVAAPFFQKIVDACLQGMQWTVDRIKSNRAQWERVLETRLSTSSG--- Q4QF31/582-940 --------------QRNSITAQRAPKSAKVIAVTPEEREAVMSIDFGGAYDFTSPDFNLFEVREKYSEPMDAAAGVVYNLLWNSGLPEKFGCREQTLLNFILQCRRRYRRVPYHNFYHVVDVCQTLHTYLYTGKASELLTELECYVLLVTALVHDLDHMGVNNSFYLKTDSPLGILSSASGNNSVLEVHHCSLAIEILSDPAADVFEGLSGQDVAYAYRALIDCVLATDMARHGDLSRVFDDM-AKAGYDSNDQESRRLVMETLIKAGDVSNVTKPFETSRMWAMAVTEEFYRQGDMEKEKGVEV-LPMFDRSKNNELARGQIGFIDFVAGKFFRDIVGNLFHGMQWCVDTVNSNRAKWQEILDGRRDSIRSSIV A7SW30/291-600 FCAQQKHQVALEVISYHCCASEKETE--EFLNSA---DLVMLP----PAYY-----------------PFSYLSALIFVLI--------FRVDLETIARFSLSVRKCYRDIPYHNWCHAFSVAHSLWIVIRDN---KSLTDYEKLSLFIAGICHDVDHRGKNNAFMLHCKTPLANLYTT----STMEWHHFKQGVFILESEGQNVFGQLDAESYRRVLELIQEAIIATDLMLFFGNKKELETLQENKAFRWEEEKHRSLIRCLLMTACDLCTSAKPWDIQVVAVNKVFEEFYIQGDEERKMGLDP-LPMMDRSKHDDLPENQVGFLKGIVRPCYSLLMDF-VPEMAPLITYVE---------------------- 5l9hA00/28-360 -----------------------------VTAITKVEREAVLVCEL-PSFDVTDVEFDLFRARESTDKPLDVAAAIAYRLLLGSGLPQKFGCSDEVLLNFILQCRKKYRNVPYHNFYHVVDVCQTIHTFLYRGNVYEKLTELECFVLLITALVHDLDHMGLNNSFYLKTESPLGILSSASGNTSVLEVHHCNLAVEILSDPESDVFDGLEGAERTLAFRSMIDCVLATDMAKHGSALEAFLA--SAADQSSDEAAFHRMTMEIILKAGDISNVTKPFDISRQWAMAVTEEFYRQGDMEKERGVEV-LPMFDRSKNMELAKGQIGFIDFVAAPFFQKIVDACLQGMQWTVDRIKSNRAQWERVLETR--------- 5l8yB00/28-360 -----------------------------VTAITKVEREAVLVCEL-PSFDVTDVEFDLFRARESTDKPLDVAAAIAYRLLLGSGLPQKFGCSDEVLLNFILQCRKKYRNVPYHNFYHVVDVCQTIHTFLYRGNVYEKLTELECFVLLITALVHDLDHMGLNNSFYLKTESPLGILSSASGNTSVLEVHHCNLAVEILSDPESDVFDGLEGAERTLAFRSMIDCVLATDMAKHGSALEAFLA--SAADQSSDEAAFHRMTMEIILKAGDISNVTKPFDISRQWAMAVTEEFYRQGDMEKERGVEV-LPMFDRSKNMELAKGQIGFIDFVAAPFFQKIVDACLQGMQWTVDRIKSNRAQWERVLETR--------- 5l8yA00/28-360 -----------------------------VTAITKVEREAVLVCEL-PSFDVTDVEFDLFRARESTDKPLDVAAAIAYRLLLGSGLPQKFGCSDEVLLNFILQCRKKYRNVPYHNFYHVVDVCQTIHTFLYRGNVYEKLTELECFVLLITALVHDLDHMGLNNSFYLKTESPLGILSSASGNTSVLEVHHCNLAVEILSDPESDVFDGLEGAERTLAFRSMIDCVLATDMAKHGSALEAFLA--SAADQSSDEAAFHRMTMEIILKAGDISNVTKPFDISRQWAMAVTEEFYRQGDMEKERGVEV-LPMFDRSKNMELAKGQIGFIDFVAAPFFQKIVDACLQGMQWTVDRIKSNRAQWERVLETR--------- 5l8cB00/28-360 -----------------------------VTAITKVEREAVLVCEL-PSFDVTDVEFDLFRARESTDKPLDVAAAIAYRLLLGSGLPQKFGCSDEVLLNFILQCRKKYRNVPYHNFYHVVDVCQTIHTFLYRGNVYEKLTELECFVLLITALVHDLDHMGLNNSFYLKTESPLGILSSASGNTSVLEVHHCNLAVEILSDPESDVFDGLEGAERTLAFRSMIDCVLATDMAKHGSALEAFLA--SAADQSSDEAAFHRMTMEIILKAGDISNVTKPFDISRQWAMAVTEEFYRQGDMEKERGVEV-LPMFDRSKNMELAKGQIGFIDFVAAPFFQKIVDACLQGMQWTVDRIKSNRAQWERVLETR--------- 5l8cA00/28-360 -----------------------------VTAITKVEREAVLVCEL-PSFDVTDVEFDLFRARESTDKPLDVAAAIAYRLLLGSGLPQKFGCSDEVLLNFILQCRKKYRNVPYHNFYHVVDVCQTIHTFLYRGNVYEKLTELECFVLLITALVHDLDHMGLNNSFYLKTESPLGILSSASGNTSVLEVHHCNLAVEILSDPESDVFDGLEGAERTLAFRSMIDCVLATDMAKHGSALEAFLA--SAADQSSDEAAFHRMTMEIILKAGDISNVTKPFDISRQWAMAVTEEFYRQGDMEKERGVEV-LPMFDRSKNMELAKGQIGFIDFVAAPFFQKIVDACLQGMQWTVDRIKSNRAQWERVLETR--------- 5g5vB00/29-360 ------------------------------TAITKVEREAVLVCEL-PSFDVTDVEFDLFRARESTDKPLDVAAAIAYRLLLGSGLPQKFGCSDEVLLNFILQCRKKYRNVPYHNFYHVVDVCQTIHTFLYRGNVYEKLTELECFVLLITALVHDLDHMGLNNSFYLKTESPLGILSSASGNTSVLEVHHCNLAVEILSDPESDVFDGLEGAERTLAFRSMIDCVLATDMAKHGSALEAFLA--SAADQSSDEAAFHRMTMEIILKAGDISNVTKPFDISRQWAMAVTEEFYRQGDMEKERGVEV-LPMFDRSKNMELAKGQIGFIDFVAAPFFQKIVDACLQGMQWTVDRIKSNRAQWERVLETR--------- 5g5vA00/25-360 ------------------------VK--RVTAITKVEREAVLVCEL-PSFDVTDVEFDLFRARESTDKPLDVAAAIAYRLLLGSGLPQKFGCSDEVLLNFILQCRKKYRNVPYHNFYHVVDVCQTIHTFLYRGNVYEKLTELECFVLLITALVHDLDHMGLNNSFYLKTESPLGILSSASGNTSVLEVHHCNLAVEILSDPESDVFDGLEGAERTLAFRSMIDCVLATDMAKHGSALEAFLA--SAADQSSDEAAFHRMTMEIILKAGDISNVTKPFDISRQWAMAVTEEFYRQGDMEKERGVEV-LPMFDRSKNMELAKGQIGFIDFVAAPFFQKIVDACLQGMQWTVDRIKSNRAQWERVLETR--------- 5g57B00/28-360 -----------------------------VTAITKVEREAVLVCEL-PSFDVTDVEFDLFRARESTDKPLDVAAAIAYRLLLGSGLPQKFGCSDEVLLNFILQCRKKYRNVPYHNFYHVVDVCQTIHTFLYRGNVYEKLTELECFVLLITALVHDLDHMGLNNSFYLKTESPLGILSSASGNTSVLEVHHCNLAVEILSDPESDVFDGLEGAERTLAFRSMIDCVLATDMAKHGSALEAFLA--SAADQSSDEAAFHRMTMEIILKAGDISNVTKPFDISRQWAMAVTEEFYRQGDMEKERGVEV-LPMFDRSKNMELAKGQIGFIDFVAAPFFQKIVDACLQGMQWTVDRIKSNRAQWERVLETR--------- 5g57A00/28-360 -----------------------------VTAITKVEREAVLVCEL-PSFDVTDVEFDLFRARESTDKPLDVAAAIAYRLLLGSGLPQKFGCSDEVLLNFILQCRKKYRNVPYHNFYHVVDVCQTIHTFLYRGNVYEKLTELECFVLLITALVHDLDHMGLNNSFYLKTESPLGILSSASGNTSVLEVHHCNLAVEILSDPESDVFDGLEGAERTLAFRSMIDCVLATDMAKHGSALEAFLA--SAADQSSDEAAFHRMTMEIILKAGDISNVTKPFDISRQWAMAVTEEFYRQGDMEKERGVEV-LPMFDRSKNMELAKGQIGFIDFVAAPFFQKIVDACLQGMQWTVDRIKSNRAQWERVLETR--------- 5g2bB00/28-360 -----------------------------VTAITKVEREAVLVCEL-PSFDVTDVEFDLFRARESTDKPLDVAAAIAYRLLLGSGLPQKFGCSDEVLLNFILQCRKKYRNVPYHNFYHVVDVCQTIHTFLYRGNVYEKLTELECFVLLITALVHDLDHMGLNNSFYLKTESPLGILSSASGNTSVLEVHHCNLAVEILSDPESDVFDGLEGAERTLAFRSMIDCVLATDMAKHGSALEAFLA--SAADQSSDEAAFHRMTMEIILKAGDISNVTKPFDISRQWAMAVTEEFYRQGDMEKERGVEV-LPMFDRSKNMELAKGQIGFIDFVAAPFFQKIVDACLQGMQWTVDRIKSNRAQWERVLETR--------- 5g2bA00/28-360 -----------------------------VTAITKVEREAVLVCEL-PSFDVTDVEFDLFRARESTDKPLDVAAAIAYRLLLGSGLPQKFGCSDEVLLNFILQCRKKYRNVPYHNFYHVVDVCQTIHTFLYRGNVYEKLTELECFVLLITALVHDLDHMGLNNSFYLKTESPLGILSSASGNTSVLEVHHCNLAVEILSDPESDVFDGLEGAERTLAFRSMIDCVLATDMAKHGSALEAFLA--SAADQSSDEAAFHRMTMEIILKAGDISNVTKPFDISRQWAMAVTEEFYRQGDMEKERGVEV-LPMFDRSKNMELAKGQIGFIDFVAAPFFQKIVDACLQGMQWTVDRIKSNRAQWERVLETR--------- 4phlB00/1-347 H-------------MASKNVPSRAVK--RVTAITKVEREAVLVCEL-PSFDVTDVEFDLFRARESTDKPLDVAAAIAYRLLLGSGLPQKFGCSDEVLLNFILQCRKKYRNVPYHNFYHVVDVCQTIHTFLYRGNVYEKLTELECFVLLITALVHDLDHMGLNNSFYLKTESPLGILSSASGNTSVLEVHHCNLAVEILSDPESDVFGGLEGAERTLAFRSMIDCVLATDMAKHGSALEAFLA--SAADQSSDEAAFHRMTMEIILKAGDISNVTKPFDISRQWAMAVTEEFYRQGDMEKERGVEV-LPMFDRSKNMELAKGQIGFIDFVAAPFFQKIVDACLQGMQWTVDRIKSNRAQWERVLETR--------- 4phlA00/1-347 H-------------MASKNVPSRAVK--RVTAITKVEREAVLVCEL-PSFDVTDVEFDLFRARESTDKPLDVAAAIAYRLLLGSGLPQKFGCSDEVLLNFILQCRKKYRNVPYHNFYHVVDVCQTIHTFLYRGNVYEKLTELECFVLLITALVHDLDHMGLNNSFYLKTESPLGILSSASGNTSVLEVHHCNLAVEILSDPESDVFGGLEGAERTLAFRSMIDCVLATDMAKHGSALEAFLA--SAADQSSDEAAFHRMTMEIILKAGDISNVTKPFDISRQWAMAVTEEFYRQGDMEKERGVEV-LPMFDRSKNMELAKGQIGFIDFVAAPFFQKIVDACLQGMQWTVDRIKSNRAQWERVLETR--------- 4i15B00/1-343 -----------------KNVPSRAVK--RVTAITKVEREAVLVCEL-PSFDVTDVEFDLFRARESTDKPLDVAAAIAYRLLLGSGLPQKFGCSDEVLLNFILQCRKKYRNVPYHNFYHVVDVCQTIHTFLYRGNVYEKLTELECFVLLITALVHDLDHMGLNNSFYLKTESPLGILSSASGNTSVLEVHHCNLAVEILSDPESDVFDGLEGAERTLAFRSMIDCVLATDMAKHGSALEAFLA--SAADQSSDEAAFHRMTMEIILKAGDISNVTKPFDISRQWAMAVTEEFYRQGDMEKERGVEV-LPMFDRSKNMELAKGQIGFIDFVAAPFFQKIVDACLQGMQWTVDRIKSNRAQWERVLETR--------- 4i15A00/1-343 -----------------KNVPSRAVK--RVTAITKVEREAVLVCEL-PSFDVTDVEFDLFRARESTDKPLDVAAAIAYRLLLGSGLPQKFGCSDEVLLNFILQCRKKYRNVPYHNFYHVVDVCQTIHTFLYRGNVYEKLTELECFVLLITALVHDLDHMGLNNSFYLKTESPLGILSSASGNTSVLEVHHCNLAVEILSDPESDVFDGLEGAERTLAFRSMIDCVLATDMAKHGSALEAFLA--SAADQSSDEAAFHRMTMEIILKAGDISNVTKPFDISRQWAMAVTEEFYRQGDMEKERGVEV-LPMFDRSKNMELAKGQIGFIDFVAAPFFQKIVDACLQGMQWTVDRIKSNRAQWERVLETR--------- 2r8qB00/1-359 --------------QRNSITAQRAPKSVKVIAVTPEEREAVMSIDFGGAYDFTSPGFNLFEVREKYSEPMDAAAGVVYNLLWNSGLPEKFGCREQTLLNFILQCRRRYRRVPYHNFYHVVDVCQTLHTYLYTGKASELLTELECYVLLVTALVHDLDHMGVNNSFYLKTDSPLGILSSASGNNSVLEVHHCSLAIEILSDPAADVFEGLSGQDVAYAYRALIDCVLATDMAKHADALSRFTEL-ATSGFEKDNDTHRRLVMETLIKAGDVSNVTKPFETSRMWAMAVTEEFYRQGDMEKEKGVEV-LPMFDRSKNNELARGQIGFIDFVAGKFFRDIVGNLFHGMQWCVDTVNSNRAKWQEILDGRRDSIRSSIV 2r8qA00/1-359 --------------QRNSITAQRAPKSVKVIAVTPEEREAVMSIDFGGAYDFTSPGFNLFEVREKYSEPMDAAAGVVYNLLWNSGLPEKFGCREQTLLNFILQCRRRYRRVPYHNFYHVVDVCQTLHTYLYTGKASELLTELECYVLLVTALVHDLDHMGVNNSFYLKTDSPLGILSSASGNNSVLEVHHCSLAIEILSDPAADVFEGLSGQDVAYAYRALIDCVLATDMAKHADALSRFTEL-ATSGFEKDNDTHRRLVMETLIKAGDVSNVTKPFETSRMWAMAVTEEFYRQGDMEKEKGVEV-LPMFDRSKNNELARGQIGFIDFVAGKFFRDIVGNLFHGMQWCVDTVNSNRAKWQEILDGRRDSIRSSIV F7BQ75/410-744 F--------------YHSQYSKADYN--ELIKAQKDDETFVLP----PNFD--RFHFSLFHLDKK---LMSYFINMVIELA-GSG--SHLLPSANVMTDFILTVRENYRDIQYHNWQHAMTVTHAMFCMLKQN--LEIFDEVERYALLVACVCHDLDHRARSNQFLQKTSHPLALLYPA----STMEYHHISMAKDILGRKESKVFQNMTNEEYEKAMYVLKEAILATDLALYFGNRGQIEELLTQGEFDFDNQQHRTSAIGLMMTACDLSSSAKDWSVTRQNLLDLHYEFWEEGDQRKKLGIKPLLPMMDRALEEDLAEGQVGFYSNVSIKCFESLARV-LPSCEPLAIRGKENLGHWRKEAEIVKEKK----- Q38F46/574-924 ---------------FNKNVPSRAVK--RVTAITKVEREAVLVCEL-PSFDVTDVEFDLFRARDTTDKPLDVAAAIAYRLLLGSGLPQKFGCSDEVLLNFILQCRKKYRNVPYHNFYHVVDVCQTIHTFLYRGNVYEKLTELECFVLLITALVHDLDHMGLNNSFYLKTESPLGILSSASGNTSVLEVHHCNLAVEILSDPESDVFGGLEGAERTLAFRSMIDCVLATDMAKHGSALEAFLA--SAADQSSDEAAFHRMTMEILLKAGDISNVTKPFDISRQWAMAVTEEFYRQGDMEKERGVEV-LPMFDRSKNMELAKGQIGFIDFVAAPFFQKIVDACLQGMQWTVDRIKSNRAQWERVLETRLSTSSG--- A4HWN7/582-940 --------------QRNSITAQRAPKRVKVIAVTPEEREAVMSIDFGDAYDFTSPDFNLFEVREKYSEPMDAAAGVVYNLLWSSGLPEKFGCREQTLLNFILQCRRRYRRVPYHNFYHVVDVCQTLHTYLYTGKASELLTELECYVLLVTALVHDLDHMGVNNSFYLKTDSPLGILSSASGNNSVLEVHHCSLAIEILSDPAADVFEGLSGQDVAYAYRALIDCVLATDMAKHADALSRFTEL-ATSGFDKENEAHRRMVMETLIKAGDVSNVTKPFETSRMWAMAVTEEFYRQGDMEKEKGVEV-LPMFDRSKNNELARGQIGFIDFVAGKFFRDIVGNLFHGMQWCVDTVNSNRAKWQEILDGRRDSTRSSIV E9AQE5/582-940 --------------QRNSITALRAPKSVKVIAVTQEEREAVMSIDFGDAYDFTSPDFSLFEVREKYSEPMDAAASVVYNLLWSSGLPEKFGCREQTLLNFILQCRRRYRRVPYHNFYHVVDVCQTLHTYLYTGKASELLTELECYVLLVTALVHDLDHMGVNNSFYLKTDSPLGILSSASGNNSVLEVHHCSLAIEILSDPAADVFEGLSGPDVAYAYRALIDCVLATDMAKHSDALVRFTEL-ATRGFDQENENHRRLVMETLIKAGDVSNVTKPFETSRMWAMAVTEEFYRQGDMEKEKGVEV-LPMFDRSKNNELARGQIGFIDFVAGKFFRDIVSNLFHGMQWCVDTVNSNRARWQAILDGRRDSTRSSIA E9BCJ3/582-940 --------------QRNSITAQRAPKSVKVIAVTPEEREAVMSIDFGDAYDFTSPDFNLFEVREKYSEPMDAAAGVVYNLLWSSGLPEKFGCREQTLLNFILQCRRRYRRVPYHNFYHVVDVCQTLHTYLYTGKASELLTELECYVLLVTALVHDLDHMGVNNSFYLKTDSPLGILSSASGNNSVLEVHHCSLAIEILSDPAADVFEGLSGQDVAYAYRALIDCVLATDMAKHADALSRFTEL-ATSGFDKENEAHRRMVMETLIKAGDVSNVTKPFETSRMWAMAVTEEFYRQGDMEKEKGVEV-LPMFDRSKNNELARGQIGFIDFVAGKFFRDIVGNLFHGMQWCVDTVNSNRAKWQEILDGRRDSTRSSIV Q8WQX9/574-924 ---------------FNKNVPSRAVK--RVTAITKVEREAVLVCEL-PSFDVTDVEFDLFRARESTDKPLDVAAAIAYRLLLGSGLPQKFGCSDEVLLNFILQCRKKYRNVPYHNFYHVVDVCQTIHTFLYRGNVYEKLTELECFVLLITALVHDLDHMGLNNSFYLKTESPLGILSSASGNTSVLEVHHCNLAVEILSDPESDVFDGLEGAERTLAFRSMIDCVLATDMAKHGSALEAFLA--SAADQSSDEAAFHRMTMEIILKAGDISNVTKPFDISRQWAMAVTEEFYRQGDMEKERGVEV-LPMFDRSKNMELAKGQIGFIDFVAAPFFQKIVDACLQGMQWTVDRIKSNRAQWERVLETRLSTSSG--- Q38F42/574-923 ---------------FNKNVPSRGVK--RVTAITNREREAVLRIEF-PNVDVTDIDFDLFQARESTDKPLDVAAAIAYRLLLGSGLPQKFGCSDEVLLNFILQCRKKYRNVPYHNFYHVVDVCQTIYTFLYRGNVYEKLTELECFVLLITALVHDLDHMGLNNSFYLKTESPLGILSSASGNKSVLEVHHCNLAVEILSDPESDVFGGLEGAERTLAFRSMIDCVLATDMARHSEFLEKYLEL-MKTSYNVDDSDHRQMTMDVLMKAGDISNVTKPFDISRQWAMAVTEEFYRQGDMEKERGVEV-LPMFDRSKNMELAKGQIGFIDFVAAPFFQKIVDACLQGMQWTVDRTKSNRAQWERVLEARSTGA----- A4HWN6/572-930 --------------QRNSITAQRAPKSVKVIAVTPEEREAVMSIDFGDAYDFTSPDFNLFEVREKYSEPMDAAAGVVYNLLWSSGLPEKFGCREQTLLNFILQCRRRYRRVPYHNFYHVVDVCQTLHTYLYTGKASELLTELECYVLLVTALVHDLDHMGVNNSFYLKTDSPLGILSSASGNNSVLEVHHCSLAIEILSDPAADVFEGLSGQDVAYAYRALIDCVLATDMARHGDLSRVFDDM-AKAGYDSNNQESRRLVMETLIKAGDVSNVTKPFETSRMWAMAVTEEFYRQGDMEKEKGVEV-LPMFDRSKNNELARGQIGFIDFVAGKFFRDIVGNLFHGMQWCVDTVNSNRAKWQEILDGRRDSTRSSIV Q6S996/582-940 --------------QRNSITAQRAPKSVKVIAVTPEEREAVMSIDFGGAYDFTSPGFNLFEVREKYSEPMDAAAGVVYNLLWNSGLPEKFGCREQTLLNFILQCRRRYRRVPYHNFYHVVDVCQTLHTYLYTGKASELLTELECYVLLVTALVHDLDHMGVNNSFYLKTDSPLGILSSASGNNSVLEVHHCSLAIEILSDPAADVFEGLSGQDVAYAYRALIDCVLATDMAKHADALSRFTEL-ATSGFEKDNDTHRRLVMETLIKAGDVSNVTKPFETSRMWAMAVTEEFYRQGDMEKEKGVEV-LPMFDRSKNNELARGQIGFIDFVAGKFFRDIVGNLFHGMQWCVDTVNSNRAKWQEILDGRRDSIRSSIV E9AQE4/572-930 --------------QRNSITALRAPKSVKVIAVTQEEREAVMSIDFGDAYDFTSPDFSLFEVREKYSEPMDAAASVVYNLLWSSGLPEKFGCREQTLLNFILQCRRRYRRVPYHNFYHVVDVCQTLHTYLYTGKASELLTELECYVLLVTALVHDLDHMGVNNSFYLKTDSPLGILSSASGNNSVLEVHHCSLAIEILSDPAADVFEGLSGPDVAYAYRALIDCVLATDMARHGDLSKVFDDM-AKAGYDSSNQESRRLVMETLIKAGDVSNVTKPFETSRMWAMAVTEEFYRQGDMEKEKGVEV-LPMFDRSKNNELARGQIGFIDFVAGKFFRDIVSNLFHGMQWCVDTVNSNRARWQAILDGRRDSTRSSIA Q6S997/572-930 --------------QRNSITAQRAPKSVKVIAVTPEEREAVMSIDFGGAYDFTSPGFNLFEVREKYSEPMDAAAGVVYNLLWNSGLPEKFGCREQTLLNFILQCRRRYRRVPYHNFYHVVDVCQTLHTYLYTGKASELLTELECYVLLVTALVHDLDHMGVNNSFYLKTDSPLGILSSASGNNSVLEVHHCSLAIEILSDPAADVFEGLSGQDVAYAYRALIDCVLATDMARHGDLSRVFDDM-AKAGYDSNDQESRRLVMETLIKAGDVSNVTKPFETSRMWAMAVTEEFYRQGDMEKEKGVEV-LPMFDRSKNNELARGQIGFIDFVAGKFFRDIVGNLFHGMQWCVDTVNSNRAKWQEILDGRRDSIRPSIV #=GC scorecons 000000000000001122222233230036565743666687434415577364447477446643348674675657497347766468665565767979669659957899967977696776665864744484878796679877776998996848979678757997696786663977969965786699766557995684746454856566767899977574555447342044554446644466657656569696876797666674677686799868996887597760999799877479857979976687457854775436577764764556766474456546111111110 #=GC scorecons_70 _____________________________*_*_*__******_______**_____*_**__**____*_*_**___*_**__**___****____**********_**_***************_**_**_*___*_**********************_********_*********____********_**_******__***_**_*_*___*_*_***********_*______*___________*____**__**___****_********_**__*****************_****_*********_***_*******_**__**__**_____***__**___**_*_*___*____________ #=GC scorecons_80 ________________________________________*_________*_____*_**________*________*_*___**____*______*__***__*__**_*****__**__*_**____*______*_***_*___**_*_*_*****_*_**_*_***__***_*_**____*_**_**___*__**_____***__*_______*_____*_*******_*_________________________________*_*_**_***____*_____*_****_***_***_***__***_****__***_*****___*____*__**______*___*_____*___*________________ #=GC scorecons_90 ________________________________________*______________________________________*_________*_________*_*__*__**___***__*___*_______*________*_*_*___**_____*****_*_**_*______**__*__*____*__*_**______**______**__*________________****_____________________________________*_*_____*___________*__**__***__*__*____***_***____*___*_**___*____*_________________________________________ //