CATH Domain 5nofA01

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.970	Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3
	1.20.970.10	Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C

Domain Context

CATH Clusters

Superfamily	Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C
Functional Family

Enzyme Information

2.4.2.18

Anthranilate phosphoribosyltransferase.

based on mapping to UniProt Q9YGB4

N-(5-phospho-D-ribosyl)-anthranilate + diphosphate = anthranilate + 5-phospho-alpha-D-ribose 1-diphosphate.

-!- In some organisms, this enzyme is part of a multifunctional protein together with one or more components of the system for biosynthesis of tryptophan (EC 4.1.1.48, EC 4.1.3.27, EC 4.2.1.20 and EC 5.3.1.24).

UniProtKB Entries (1)

Q9YGB4

TRPD_THEKO

Thermococcus kodakarensis KOD1

Anthranilate phosphoribosyltransferase

PDB Structure

PDB	5NOF
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Anthranilate phosphoribosyltransferase from the hyperthermophilic archaeon Thermococcus kodakarensis shows maximum activity with zinc and forms a unique dimeric structure. Perveen, S., Rashid, N., Tang, X.F., Imanaka, T., Papageorgiou, A.C. FEBS Open Bio