CATH Classification

Domain Context

CATH Clusters

Superfamily 2.30.30.140
Functional Family Histone-lysine N-methyltransferase

Enzyme Information

2.1.1.43
Histone-lysine N-methyltransferase.
based on mapping to UniProt Q15047
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].

UniProtKB Entries (1)

Q15047
SETB1_HUMAN
Homo sapiens
Histone-lysine N-methyltransferase SETDB1

PDB Structure

PDB 5KH6
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
SETDB1 in complex with a fragment candidate
Walker, J.R., Harding, R.J., Mader, P., Dobrovetsky, E., Dong, A., Collins, P., Pearce, N., Brandao-Neto, J., Douangamath, A., von Delft, F., Brown, P.J., Schapira, M., Arrowsmith, C.H., Edwards, A.M., Santhakumar, V., Structural Genomics Consortium (SGC)
To be published
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