CATH Domain 5j59A02

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.170	Beta Complex
	2.170.220	Methionyl-trna Synthetase; domain 2
	2.170.220.10

Domain Context

CATH Clusters

Superfamily	2.170.220.10
Functional Family	Methionine--tRNA ligase

Enzyme Information

UniProtKB Entries (1)

Q38C91_TRYB2

Trypanosoma brucei brucei TREU927

Methionyl-tRNA synthetase, putative

PDB Structure

PDB	5J59
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structure-guided design of novel Trypanosoma brucei Methionyl-tRNA synthetase inhibitors. Huang, W., Zhang, Z., Barros-Alvarez, X., Koh, C.Y., Ranade, R.M., Gillespie, J.R., Creason, S.A., Shibata, S., Verlinde, C.L., Hol, W.G., Buckner, F.S., Fan, E. Eur J Med Chem