CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.40 | Beta Barrel |
|
2.40.340 | Beta-clip |
|
2.40.340.10 | MoeA, C-terminal, domain IV |
Domain Context
CATH Clusters
| Superfamily | MoeA, C-terminal, domain IV |
| Functional Family | Molybdopterin molybdenumtransferase |
Enzyme Information
| 2.7.7.75 |
Molybdopterin adenylyltransferase.
based on mapping to UniProt Q39054
ATP + molybdopterin = diphosphate + adenylyl-molybdopterin.
-!- Catalyzes the activation of molybdopterin for molybdenum insertion. -!- In eukaryotes, this reaction is catalyzed by the C-terminal domain of a fusion protein that also includes molybdopterin molybdotransferase (EC 2.10.1.1). -!- The reaction requires a divalent cation such as Mg(2+) or Mn(2+). -!- Catalyzes the activation of molybdopterin for molybdenum insertion. -!- In eukaryotes, this reaction is catalyzed by the C-terminal domain of a fusion protein that also includes EC 2.10.1.1. -!- Formerly EC 2.7.7.n5.
|
| 2.10.1.1 |
Molybdopterin molybdotransferase.
based on mapping to UniProt Q39054
Adenylyl-molybdopterin + molybdate = molybdenum cofactor + AMP.
-!- Catalyzes the insertion of molybdenum into the ene-dithiol group of molybdopterin. -!- In eukaryotes this reaction is catalyzed by the N-terminal domain of a fusion protein whose C-terminal domain catalyzes EC 2.7.7.75.
|
UniProtKB Entries (1)
| Q39054 |
CNX1_ARATH
Arabidopsis thaliana
Molybdopterin biosynthesis protein CNX1
|
PDB Structure
| PDB | 5G2R |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Dimerization of the Plant Molybdenum Insertase Cnx1E is Required for Synthesis of the Molybdenum Cofactor.
Biochem.J.
|
