CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.10 | Arc Repressor Mutant, subunit A |
|
1.10.10.60 | Homeodomain-like |
Domain Context
CATH Clusters
| Superfamily | Homeodomain-like |
| Functional Family | TetR family transcriptional regulator |
Enzyme Information
UniProtKB Entries (1)
| P9WMC1 |
ETHR_MYCTU
Mycobacterium tuberculosis H37Rv
HTH-type transcriptional regulator EthR
|
PDB Structure
| PDB | 5F27 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
A fragment merging approach towards the development of small molecule inhibitors of Mycobacterium tuberculosis EthR for use as ethionamide boosters.
Org.Biomol.Chem.
|
