CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.30 | 2-Layer Sandwich | |
3.30.1600 | SIR2/SIRT2 'Small Domain' | |
3.30.1600.10 | SIR2/SIRT2 'Small Domain' |
Domain Context
CATH Clusters
Superfamily | SIR2/SIRT2 'Small Domain' |
Functional Family |
Enzyme Information
3.5.1.- |
In linear amides.
based on mapping to UniProt Q96EB6
|
UniProtKB Entries (1)
Q96EB6 |
SIR1_HUMAN
Homo sapiens
NAD-dependent protein deacetylase sirtuin-1
|
PDB Structure
PDB | 5BTR |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Structural basis for allosteric, substrate-dependent stimulation of SIRT1 activity by resveratrol
Genes Dev.
|