CATH Domain 4zt6A02

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.170	Beta Complex
	2.170.220	Methionyl-trna Synthetase; domain 2
	2.170.220.10

Domain Context

CATH Clusters

Superfamily	2.170.220.10
Functional Family	Methionine--tRNA ligase

Enzyme Information

UniProtKB Entries (1)

Q38C91_TRYB2

Trypanosoma brucei brucei TREU927

Methionyl-tRNA synthetase, putative

PDB Structure

PDB	4ZT6
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	5-Fluoroimidazo[4,5-b]pyridine Is a Privileged Fragment That Conveys Bioavailability to Potent Trypanosomal Methionyl-tRNA Synthetase Inhibitors. Zhang, Z., Koh, C.Y., Ranade, R.M., Shibata, S., Gillespie, J.R., Hulverson, M.A., Huang, W., Nguyen, J., Pendem, N., Gelb, M.H., Verlinde, C.L., Hol, W.G., Buckner, F.S., Fan, E. Acs Infect Dis.