CATH Domain 4xuzA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.710	Beta-lactamase
	3.40.710.10	DD-peptidase/beta-lactamase superfamily

Domain Context

CATH Clusters

Superfamily	DD-peptidase/beta-lactamase superfamily
Functional Family

Enzyme Information

UniProtKB Entries (1)

S5LVN3_KLEPN

Klebsiella pneumoniae subsp. pneumoniae

Beta-lactamase

PDB Structure

PDB	4XUZ
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Discovery of a Cyclic Boronic Acid beta-Lactamase Inhibitor (RPX7009) with Utility vs Class A Serine Carbapenemases. Hecker, S.J., Reddy, K.R., Totrov, M., Hirst, G.C., Lomovskaya, O., Griffith, D.C., King, P., Tsivkovski, R., Sun, D., Sabet, M., Tarazi, Z., Clifton, M.C., Atkins, K., Raymond, A., Potts, K.T., Abendroth, J., Boyer, S.H., Loutit, J.S., Morgan, E.E., Durso, S., Dudley, M.N. J.Med.Chem.