CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.20 | Up-down Bundle |
|
1.20.1440 | de novo design (two linked rop proteins) |
|
1.20.1440.180 | KEN domain |
Domain Context
CATH Clusters
| Superfamily | KEN domain |
| Functional Family | Ribonuclease L |
Enzyme Information
| 3.1.26.- |
Endoribonucleases producing 5'-phosphomonoesters.
based on mapping to UniProt Q05823
|
UniProtKB Entries (1)
| Q05823 |
RN5A_HUMAN
Homo sapiens
2-5A-dependent ribonuclease
|
PDB Structure
| PDB | 4OAU |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structure of human RNase L reveals the basis for regulated RNA decay in the IFN response.
Science
|
