CATH Domain 4niyA01

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.40	Beta Barrel
	2.40.10	Thrombin, subunit H
	2.40.10.10	Trypsin-like serine proteases

Domain Context

CATH Clusters

Superfamily	Trypsin-like serine proteases
Functional Family	Cationic trypsin

Enzyme Information

3.4.21.4

Trypsin.

based on mapping to UniProt P00760

Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.

-!- Belongs to peptidase family S1. -!- Formerly EC 3.4.4.4.

UniProtKB Entries (2)

P23827	ECOT_ECOLI Escherichia coli K-12 Ecotin
P00760	TRY1_BOVIN Bos taurus Cationic trypsin

PDB Structure

PDB	4NIY
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	N-terminal protein modification by substrate-activated reverse proteolysis. Liebscher, S., Schopfel, M., Aumuller, T., Sharkhuukhen, A., Pech, A., Hoss, E., Parthier, C., Jahreis, G., Stubbs, M.T., Bordusa, F. Angew.Chem.Int.Ed.Engl.