CATH Domain 4m3fA01

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.10	Arc Repressor Mutant, subunit A
	1.10.10.60	Homeodomain-like

Domain Context

CATH Clusters

Superfamily	Homeodomain-like
Functional Family	TetR family transcriptional regulator

Enzyme Information

UniProtKB Entries (1)

ETHR_MYCTO

Mycobacterium tuberculosis CDC1551

HTH-type transcriptional regulator EthR

PDB Structure

PDB	4M3F
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Ligand Efficiency Driven Design of New Inhibitors of Mycobacterium tuberculosis Transcriptional Repressor EthR Using Fragment Growing, Merging, and Linking Approaches. Villemagne, B., Flipo, M., Blondiaux, N., Crauste, C., Malaquin, S., Leroux, F., Piveteau, C., Villeret, V., Brodin, P., Villoutreix, B.O., Sperandio, O., Soror, S.H., Wohlkonig, A., Wintjens, R., Deprez, B., Baulard, A.R., Willand, N. J.Med.Chem.