CATH Domain 4iubL00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.645	Cytochrome-c3 Hydrogenase; chain B
	1.10.645.10	Cytochrome-c3 Hydrogenase, chain B

Domain Context

CATH Clusters

Superfamily	Cytochrome-c3 Hydrogenase, chain B
Functional Family	Hydrogenase 2 large subunit

Enzyme Information

1.12.99.6

Hydrogenase (acceptor).

based on mapping to UniProt P31891

H(2) + A = AH(2).

-!- Uses molecular hydrogen for the reduction of a variety of substances.

UniProtKB Entries (1)

MBHL_CUPNH

Cupriavidus necator H16

Uptake hydrogenase large subunit

PDB Structure

PDB	4IUB
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Reversible [4Fe-3S] cluster morphing in an O2-tolerant [NiFe] hydrogenase. Frielingsdorf, S., Fritsch, J., Schmidt, A., Hammer, M., Lowenstein, J., Siebert, E., Pelmenschikov, V., Jaenicke, T., Kalms, J., Rippers, Y., Lendzian, F., Zebger, I., Teutloff, C., Kaupp, M., Bittl, R., Hildebrandt, P., Friedrich, B., Lenz, O., Scheerer, P. Nat.Chem.Biol.