CATH Domain 4i0cA00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.530	Lysozyme
	1.10.530.10

Domain Context

CATH Clusters

Superfamily	1.10.530.10
Functional Family	Lysozyme C

Enzyme Information

3.2.1.17

Lysozyme.

based on mapping to UniProt P61626

Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl- D-glucosamine residues in chitodextrins.

-!- Cf. EC 3.2.1.14.

UniProtKB Entries (1)

P61626

LYSC_HUMAN

Homo sapiens

Lysozyme C

PDB Structure

PDB	4I0C
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	A nanobody binding to non-amyloidogenic regions of the protein human lysozyme enhances partial unfolding but inhibits amyloid fibril formation. De Genst, E., Chan, P.H., Pardon, E., Hsu, S.T., Kumita, J.R., Christodoulou, J., Menzer, L., Chirgadze, D.Y., Robinson, C.V., Muyldermans, S., Matagne, A., Wyns, L., Dobson, C.M., Dumoulin, M. J.Phys.Chem.B