CATH Classification

Domain Context

CATH Clusters

Superfamily Aldehyde Dehydrogenase; Chain A, domain 1
Functional Family Cytosolic 10-formyltetrahydrofolate dehydrogenase

Enzyme Information

1.5.1.6
Formyltetrahydrofolate dehydrogenase.
based on mapping to UniProt P28037
10-formyltetrahydrofolate + NADP(+) + H(2)O = tetrahydrofolate + CO(2) + NADPH.

UniProtKB Entries (1)

P28037
AL1L1_RAT
Rattus norvegicus
Cytosolic 10-formyltetrahydrofolate dehydrogenase

PDB Structure

PDB 4GO0
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The mechanism of discrimination between oxidized and reduced coenzyme in the aldehyde dehydrogenase domain of Aldh1l1.
Tsybovsky, Y., Malakhau, Y., Strickland, K.C., Krupenko, S.A.
Chem.Biol.Interact
CATH-Gene3D is a Global Biodata Core Resource Learn more...