CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.130 | 7 Propeller |
|
2.130.10 | Methylamine Dehydrogenase; Chain H |
|
2.130.10.10 | YVTN repeat-like/Quinoprotein amine dehydrogenase |
Domain Context
CATH Clusters
| Superfamily | YVTN repeat-like/Quinoprotein amine dehydrogenase |
| Functional Family | PAN2-PAN3 deadenylation complex catalytic subunit PAN2 |
Enzyme Information
| 3.1.13.4 |
Poly(A)-specific ribonuclease.
based on mapping to UniProt G0SAK8
Exonucleolytic cleavage of poly(A) to 5'-AMP.
-!- Cleaves poly(A) in either the single- or double-stranded form.
|
UniProtKB Entries (1)
| G0SAK8 |
PAN2_CHATD
Chaetomium thermophilum var. thermophilum DSM 1495
PAN2-PAN3 deadenylation complex catalytic subunit PAN2
|
PDB Structure
| PDB | 4D0K |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
An Asymmetric Pan3 Dimer Recruits a Single Pan2 Exonuclease to Mediate Mrna Deadenylation and Decay.
Nat.Struct.Mol.Biol.
|
