CATH Domain 3vavA00

Level	CATH Code	Description
	3	Alpha Beta
	3.20	Alpha-Beta Barrel
	3.20.20	TIM Barrel
	3.20.20.60	Phosphoenolpyruvate-binding domains

Superfamily	Phosphoenolpyruvate-binding domains
Functional Family	3-methyl-2-oxobutanoate hydroxymethyltransferase

2.1.2.11

3-methyl-2-oxobutanoate hydroxymethyltransferase.

based on mapping to UniProt Q2SYZ1

5,10-methylenetetrahydrofolate + 3-methyl-2-oxobutanoate + H(2)O = tetrahydrofolate + 2-dehydropantoate.

PANB_BURTA

Burkholderia thailandensis E264

3-methyl-2-oxobutanoate hydroxymethyltransferase

PDB	3VAV
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Combining functional and structural genomics to sample the essential Burkholderia structome. Baugh, L., Gallagher, L.A., Patrapuvich, R., Clifton, M.C., Gardberg, A.S., Edwards, T.E., Armour, B., Begley, D.W., Dieterich, S.H., Dranow, D.M., Abendroth, J., Fairman, J.W., Fox, D., Staker, B.L., Phan, I., Gillespie, A., Choi, R., Nakazawa-Hewitt, S., Nguyen, M.T., Napuli, A., Barrett, L., Buchko, G.W., Stacy, R., Myler, P.J., Stewart, L.J., Manoil, C., Van Voorhis, W.C. Plos One