CATH Domain 3t06A02

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.30	Roll
	2.30.29	PH-domain like
	2.30.29.30	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)

Domain Context

CATH Clusters

Superfamily	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Functional Family	Rho guanine nucleotide exchange factor 1

Enzyme Information

UniProtKB Entries (1)

RHOA_HUMAN

Homo sapiens

Transforming protein RhoA

PDB Structure

PDB	3T06
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Insights into the Molecular Activation Mechanism of the RhoA-specific Guanine Nucleotide Exchange Factor, PDZRhoGEF. Bielnicki, J.A., Shkumatov, A.V., Derewenda, U., Somlyo, A.V., Svergun, D.I., Derewenda, Z.S. J.Biol.Chem.