CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.90 | Alpha-Beta Complex | |
3.90.1420 | set domain protein methyltransferase, domain 2 | |
3.90.1420.10 | Rubisco LSMT, substrate-binding domain |
Domain Context
CATH Clusters
Superfamily | Rubisco LSMT, substrate-binding domain |
Functional Family | histone-lysine N-methyltransferase setd3 isoform X1 |
Enzyme Information
2.1.1.85 |
Protein-histidine N-methyltransferase.
based on mapping to UniProt Q86TU7
S-adenosyl-L-methionine + protein L-histidine = S-adenosyl-L-homocysteine + protein N(tau)-methyl-L-histidine.
-!- Highly specific for histidine residues, for example, in actin.
|
UniProtKB Entries (1)
Q86TU7 |
SETD3_HUMAN
Homo sapiens
Actin-histidine N-methyltransferase
|
PDB Structure
PDB | 3SMT |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Crystal structure of human SET domain-containing protein3
To be Published
|