CATH Classification
Level | CATH Code | Description |
---|---|---|
4 | Few Secondary Structures | |
4.10 | Irregular | |
4.10.410 | Factor Xa Inhibitor | |
4.10.410.10 | Pancreatic trypsin inhibitor Kunitz domain |
Domain Context
CATH Clusters
Superfamily | Pancreatic trypsin inhibitor Kunitz domain |
Functional Family | Pancreatic trypsin inhibitor |
Enzyme Information
UniProtKB Entries (2)
P00974 |
BPT1_BOVIN
Bos taurus
Pancreatic trypsin inhibitor
|
P35030 |
TRY3_HUMAN
Homo sapiens
Trypsin-3
|
PDB Structure
PDB | 3P95 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
The P2' residue is a key determinant of mesotrypsin specificity: engineering a high-affinity inhibitor with anticancer activity.
Biochem.J.
|