CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.220 | Annexin V; domain 1 |
|
1.10.220.160 |
Domain Context
CATH Clusters
| Superfamily | 1.10.220.160 |
| Functional Family | Histone-lysine N-methyltransferase SMYD3 |
Enzyme Information
| 2.1.1.43 |
Histone-lysine N-methyltransferase.
based on mapping to UniProt Q9H7B4
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].
|
UniProtKB Entries (1)
| Q9H7B4 |
SMYD3_HUMAN
Homo sapiens
Histone-lysine N-methyltransferase SMYD3
|
PDB Structure
| PDB | 3OXG |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural and biochemical studies of human lysine methyltransferase Smyd3 reveal the important functional roles of its post-SET and TPR domains and the regulation of its activity by DNA binding.
Nucleic Acids Res.
|
