CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.357 | Tetracycline Repressor; domain 2 |
|
1.10.357.170 |
Domain Context
CATH Clusters
| Superfamily | 1.10.357.170 |
| Functional Family |
Enzyme Information
| 2.7.7.n6 |
Guanine phosphate-protein transferase.
based on mapping to UniProt Q29ST3
GTP + [protein]-L-tyrosine = diphosphate + [protein]-O(4)-(5'-guanylyl)- L-tyrosine.
-!- The enzyme from Legionella also functions as EC 2.7.7.n1.
|
| 2.7.7.n1 |
Protein adenylyltransferase.
based on mapping to UniProt Q29ST3
(1) ATP + [protein]-L-tyrosine = diphosphate + [protein]-O(4)- (5'-adenylyl)-L-tyrosine. (2) ATP + [protein]-L-threonine = diphosphate + [protein]-O(4)- (5'-adenylyl)-L-threonine.
|
UniProtKB Entries (1)
| Q29ST3 |
DRRA_LEGPN
Legionella pneumophila
Multifunctional virulence effector protein DrrA
|
PDB Structure
| PDB | 3NKU |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The Legionella effector protein DrrA AMPylates the membrane traffic regulator Rab1b.
Science
|
