CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.640 | Aspartate Aminotransferase; domain 2 |
|
3.40.640.10 | Type I PLP-dependent aspartate aminotransferase-like (Major domain) |
Domain Context
CATH Clusters
| Superfamily | Type I PLP-dependent aspartate aminotransferase-like (Major domain) |
| Functional Family |
Enzyme Information
| 2.6.1.51 |
Serine--pyruvate transaminase.
based on mapping to UniProt O35423
L-serine + pyruvate = 3-hydroxypyruvate + L-alanine.
-!- The liver enzyme may be identical with EC 2.6.1.44.
|
| 2.6.1.44 |
Alanine--glyoxylate transaminase.
based on mapping to UniProt O35423
L-alanine + glyoxylate = pyruvate + glycine.
-!- With one component of the animal enzyme, 2-oxobutanoate can replace glyoxylate. -!- A second component also catalyzes the reaction of EC 2.6.1.51.
|
UniProtKB Entries (1)
| O35423 |
SPYA_MOUSE
Mus musculus
Serine--pyruvate aminotransferase, mitochondrial
|
PDB Structure
| PDB | 3KGX |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structure of Putative aminotransferase (AAH25799.1) from MUS MUSCULUS at 1.80 A resolution
To be published
|
