CATH Classification

Domain Context

CATH Clusters

Superfamily Zn peptidases
Functional Family

Enzyme Information

3.4.11.10
Bacterial leucyl aminopeptidase.
based on mapping to UniProt Q5H4N2
Release of an N-terminal amino acid, preferentially leucine, but not glutamic or aspartic acids.
-!- Similar aminopeptidases were isolated from Escherichia coli and Staphylococcus thermophilus. -!- Belongs to peptidase families M17 and M28.
3.4.11.1
Leucyl aminopeptidase.
based on mapping to UniProt Q5H4N2
Release of an N-terminal amino acid, Xaa-|-Yaa-, in which Xaa is preferably Leu, but may be other amino acids including Pro although not Arg or Lys, and Yaa may be Pro. Amino acid amides and methyl esters are also readily hydrolyzed, but rates on arylamides are exceedingly low.
-!- Is activated by heavy metal ions. -!- Belongs to peptidase family M17. -!- Formerly EC 3.4.1.1.

UniProtKB Entries (1)

Q5H4N2
AMPA_XANOR
Xanthomonas oryzae pv. oryzae KACC 10331
Probable cytosol aminopeptidase

PDB Structure

PDB 3JRU
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of Leucyl Aminopeptidase (pepA) from Xoo0834,Xanthomonas oryzae pv. oryzae KACC10331
Natarajan, S., Huynh, K.-H., Kang, L.W.
to be published
CATH-Gene3D is a Global Biodata Core Resource Learn more...