CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.710 | Beta-lactamase |
|
3.40.710.10 | DD-peptidase/beta-lactamase superfamily |
Domain Context
CATH Clusters
| Superfamily | DD-peptidase/beta-lactamase superfamily |
| Functional Family |
Enzyme Information
| 2.3.1.238 |
Monacolin J acid methylbutanoate transferase.
based on mapping to UniProt Q9Y7D1
Monacolin J acid + (S)-2-methylbutanoyl-[2-methylbutanoate polyketide synthase] = lovastatin acid + [2-methylbutanoate polyketide synthase].
-!- The enzyme catalyzes the ultimate reaction in the lovastatin biosynthesis pathway of the filamentous fungus Aspergillus terreus.
|
UniProtKB Entries (1)
| Q9Y7D1 |
LOVD_ASPTE
Aspergillus terreus
Monacolin J acid methylbutanoyltransferase
|
PDB Structure
| PDB | 3HLG |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Directed evolution and structural characterization of a simvastatin synthase
Chem.Biol.
|
