CATH Classification
Level | CATH Code | Description |
---|---|---|
2 | Mainly Beta | |
2.60 | Sandwich | |
2.60.40 | Immunoglobulin-like | |
2.60.40.10 | Immunoglobulins |
Domain Context
CATH Clusters
Superfamily | Immunoglobulins |
Functional Family | Immunoglobulin heavy constant gamma 1 |
Enzyme Information
UniProtKB Entries (1)
P20701 |
ITAL_HUMAN
Homo sapiens
Integrin alpha-L
|
PDB Structure
PDB | 3EOA |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Efalizumab binding to the LFA-1 alphaL I domain blocks ICAM-1 binding via steric hindrance.
Proc.Natl.Acad.Sci.USA
|