CATH Classification

Domain Context

CATH Clusters

Superfamily ATP-grasp fold, B domain
Functional Family Phosphoribosylaminoimidazole-succinocarboxamide synthase

Enzyme Information

6.3.2.6
Phosphoribosylaminoimidazolesuccinocarboxamide synthase.
based on mapping to UniProt Q58987
ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate = ADP + phosphate + (S)-2-(5-amino-1-(5-phospho-D- ribosyl)imidazole-4-carboxamido)succinate.
-!- Forms part of the purine biosynthesis pathway.

UniProtKB Entries (1)

Q58987
PUR7_METJA
Methanocaldococcus jannaschii DSM 2661
Phosphoribosylaminoimidazole-succinocarboxamide synthase

PDB Structure

PDB 2YZL
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of phosphoribosylaminoimidazole-succinocarboxamide synthase with ADP from Methanocaldococcus jannaschii
Kanagawa, M., Baba, S., Fukui, K., Kuramitsu, S., Yokoyama, S., Kawai, G., Sampei, G.
To be Published
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