CATH Classification

Domain Context

CATH Clusters

Superfamily S15/NS1, RNA-binding
Functional Family 30S ribosomal protein S15

Enzyme Information

UniProtKB Entries (2)

A0A0N0BLS5
RS17_THEAQ
Thermus aquaticus
30S ribosomal protein S17
Q5SHP2
RS19_THET8
Thermus thermophilus HB8
30S ribosomal protein S19

PDB Structure

PDB 2HHH
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The antibiotic kasugamycin mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation.
Schluenzen, F., Takemoto, C., Wilson, D.N., Kaminishi, T., Harms, J.M., Hanawa-Suetsugu, K., Szaflarski, W., Kawazoe, M., Shirouzo, M., Nierhaus, K.H., Yokoyama, S., Fucini, P.
Nat.Struct.Mol.Biol.
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