CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.60 | 4-Layer Sandwich | |
3.60.15 | Metallo-beta-lactamase; Chain A | |
3.60.15.10 | Ribonuclease Z/Hydroxyacylglutathione hydrolase-like |
Domain Context
CATH Clusters
Superfamily | Ribonuclease Z/Hydroxyacylglutathione hydrolase-like |
Functional Family |
Enzyme Information
3.5.2.6 |
Beta-lactamase.
based on mapping to UniProt P25910
A beta-lactam + H(2)O = a substituted beta-amino acid.
-!- Zinc is only requires in class-B enzymes. -!- A group of enzymes of varying specificity hydrolyzing beta-lactams; some act more rapidly on penicillins, some more rapidly on cephalosporins. -!- Formerly EC 3.5.2.8.
|
UniProtKB Entries (1)
P25910 |
BLAB_BACFG
Bacteroides fragilis
Metallo-beta-lactamase type 2
|
PDB Structure
PDB | 2BMI |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | Escherichia |
Primary Citation |
X-ray structure of the ZnII beta-lactamase from Bacteroides fragilis in an orthorhombic crystal form.
Acta Crystallogr.,Sect.D
|