CATH Domain 1zxlA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.720	NAD(P)-binding Rossmann-like Domain

Domain Context

CATH Clusters

Superfamily	NAD(P)-binding Rossmann-like Domain
Functional Family

Enzyme Information

UniProtKB Entries (1)

Q9BJJ9_PLAFA

Plasmodium falciparum

Enoyl-ACP reductase

PDB Structure

PDB	1ZXL
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Synthesis, biological activity, and X-ray crystal structural analysis of diaryl ether inhibitors of malarial enoyl acyl carrier protein reductase. Part 1: 4'-Substituted triclosan derivatives. Freundlich, J.S., Anderson, J.W., Sarantakis, D., Shieh, H.M., Yu, M., Valderramos, J.C., Lucumi, E., Kuo, M., Jacobs, W.R., Fidock, D.A., Schiehser, G.A., Jacobus, D.P., Sacchettini, J.C. Bioorg.Med.Chem.Lett.