CATH Domain 1w0oA01

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.120	Jelly Rolls
	2.60.120.200

Domain Context

CATH Clusters

Superfamily	2.60.120.200
Functional Family

Enzyme Information

3.2.1.18

Exo-alpha-sialidase.

based on mapping to UniProt P0C6E9

Hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)- glycosidic linkages of terminal sialic acid residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates.

-!- The enzyme does not act on 4-O-acetylated sialic acids. -!- An endo-alpha-sialidase activity is listed as EC 3.2.1.129. -!- See also EC 4.2.2.15.

UniProtKB Entries (1)

P0C6E9

NANH_VIBCH

Vibrio cholerae O1 biovar El Tor str. N16961

Sialidase

PDB Structure

PDB	1W0O
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Sialic Acid Recognition by Vibrio Cholerae Neuraminidase Moustafa, I., Connaris, H., Taylor, M., Zaitsev, V., Wilsonm, J.C., Kiefel, J., Von-Itzstein, M., Taylor, G. J.Biol.Chem.