CATH Domain 1uxmA00

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.40	Immunoglobulin-like
	2.60.40.200	Superoxide dismutase, copper/zinc binding domain

Domain Context

CATH Clusters

Superfamily	Superoxide dismutase, copper/zinc binding domain
Functional Family	Superoxide dismutase [Cu-Zn]

Enzyme Information

1.15.1.1

Superoxide dismutase.

based on mapping to UniProt P00441

2 superoxide + 2 H(+) = O(2) + H(2)O(2).

UniProtKB Entries (1)

SODC_HUMAN

Homo sapiens

Superoxide dismutase [Cu-Zn]

PDB Structure

PDB	1UXM
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Dimer Destabilization in Superoxide Dismutase May Result in Disease-Causing Properties: Structures of Motor Neuron Disease Mutants Hough, M.A., Grossmann, J.G., Antonyuk, S.V., Strange, R.W., Doucette, P.A., Rodriguez, J.A., Whitson, L.J., Hart, P.J., Hayward, L.J., Valentine, J.S., Hasnain, S.S. Proc.Natl.Acad.Sci.USA