CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.630 | Aminopeptidase |
|
3.40.630.10 | Zn peptidases |
Domain Context
CATH Clusters
| Superfamily | Zn peptidases |
| Functional Family | M28 family peptidase |
Enzyme Information
| 3.4.11.24 |
Aminopeptidase S.
based on mapping to UniProt P80561
Release of an N-terminal amino acid with a preference for large hydrophobic amino-terminus residues.
-!- Activated by Ca(2+). -!- In the presence of Ca(2+), the best substrates are Leu-Phe, Leu-Ser, Leu-pNA (aminoacyl-p-nitroanilide), Phe-Phe-Phe and Phe-Phe. -!- Peptides with proline in the P1' position are not substrates. -!- Belongs to peptidase family M28. -!- Formerly EC 3.4.11.n1.
|
UniProtKB Entries (1)
| P80561 |
APX_STRGG
Streptomyces griseus subsp. griseus NBRC 13350
Aminopeptidase S
|
PDB Structure
| PDB | 1TF8 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Binding of inhibitory aromatic amino acids to Streptomyces griseus aminopeptidase.
Acta Crystallogr.,Sect.D
|
