CATH Domain 1rzqA02

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.40	Immunoglobulin-like
	2.60.40.420	Cupredoxins - blue copper proteins

Domain Context

CATH Clusters

Superfamily	Cupredoxins - blue copper proteins
Functional Family

Enzyme Information

1.7.2.1

Nitrite reductase (NO-forming).

based on mapping to UniProt P25006

Nitric oxide + H(2)O + ferricytochrome c = nitrite + ferrocytochrome c + 2 H(+).

-!- The reaction is catalyzed by two types of enzymes, found in the perimplasm of denitrifying bacteria. -!- One type comprises proteins containing multiple copper centers, the other a heme protein, cytochrome cd1. -!- Acceptors include c-type cytochromes such as cytochrome c-550 or cytochrome c-551 from Paracoccus denitrificans or Pseudomonas aeruginosa, and small blue copper proteins such as azurin and pseudoazurin. -!- Cytochrome cd1 also has oxidase and hydroxylamine reductase activities. -!- May also catalyze the reaction of EC 1.7.99.1 since this is a well- known activity of cytochrome cd1. -!- Formerly EC 1.6.6.5, EC 1.7.99.3 and EC 1.9.3.2.

UniProtKB Entries (1)

P25006

NIR_ACHCY

Achromobacter cycloclastes

Copper-containing nitrite reductase

PDB Structure

PDB	1RZQ
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	pH-profile crystal structure studies of C-terminal despentapeptide nitrite reductase from Achromobacter cycloclastes Li, H.T., Wang, C., Chang, T., Chang, W.C., Liu, M.Y., Le Gall, J., Gui, L.L., Zhang, J.P., An, X.M., Chang, W.R. Biochem.Biophys.Res.Commun.